Investigation of design space for freeze-drying: Use of modeling for primary drying segment of a freeze-drying cycle

AAPS PharmSciTech

Volumn 12, Issue 3, 2011, Pages 854-861

  Koganti, Venkat Rao ^a   Shalaev, Evgenyi Y ^a   Berry, Mark R ^a   Osterberg, Thomas ^a   Youssef, Maickel ^a   Hiebert, David N ^a   Kanka, Frank A ^a   Nolan, Martin ^a   Barrett, Rosemary ^a   Scalzo, Gioval ^a   Fitzpatrick, Gillian ^a   Fitzgibbon, Niall ^a   Luthra, Sumit ^a   Zhang, Liling ^a  

^a PFIZER INC   (United States)

Author keywords

design space; freeze drying; mathematical modeling; quality by design

Indexed keywords

ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; FREEZE DRYING; HEAT TRANSFER; MATHEMATICAL MODEL; PRIORITY JOURNAL; PROCESS DESIGN;

ALGORITHMS; COMPUTER SIMULATION; FREEZE DRYING; MODELS, CHEMICAL; QUALITY CONTROL; TECHNOLOGY, PHARMACEUTICAL; TEMPERATURE; VOLATILIZATION; WATER;

EID: 80052562774     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-011-9645-7     Document Type: Article

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