Novel platinum-N-heterocyclic carbene complex is more cardiotoxic than cis-platin in rats

Human and Experimental Toxicology

Volumn 30, Issue 9, 2011, Pages 1342-1349

  Ciftci, Osman ^a   Ozdemir, Ilknur ^a   Vardi, Nigar ^a   Gurbuz, Nevin ^a  

^a INONU UNIVERSITY   (Turkey)

Author keywords

cardiotoxicity; Cis platin; oxidative stress; platin NHC complex

Indexed keywords

CARBENE; CISPLATIN; PLATINUM N HETEROCYCLIC CARBENE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; CARDIOTOXICITY; CLINICAL ASSESSMENT; CONTROLLED STUDY; DOSE RESPONSE; DRUG STRUCTURE; DRUG SYNTHESIS; HEART MUSCLE INJURY; HISTOPATHOLOGY; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT;

ANIMALS; ANTINEOPLASTIC AGENTS; CISPLATIN; HEART; HETEROCYCLIC COMPOUNDS; INJECTIONS, INTRAPERITONEAL; MALE; METHANE; MYOCARDIUM; ORGANOPLATINUM COMPOUNDS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 80052553891     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327110390064     Document Type: Article

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