-
1
-
-
14844341251
-
Identification of combinatorial drug regimens for treatment of Huntington's disease using Drosophila
-
DOI 10.1073/pnas.0500055102
-
Agrawal N, Pallos J, Slepko N, Apostol BL, Bodai L, Chang LW, Chiang AS, Thompson LM, Marsh JL (2005) Identification of combinatorial drug regimens for treatment of Huntington's disease using Drosophila. Proc Natl Acad Sci USA 102(10): 3777-3781 (Pubitemid 40354688)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.10
, pp. 3777-3781
-
-
Agrawal, N.1
Pallos, J.2
Slepko, N.3
Apostol, B.L.4
Bodai, L.5
Chang, L.-W.6
Chiang, A.-S.7
Thompson, L.M.8
Marsh, J.L.9
-
2
-
-
45549095070
-
Patterned dispersion of nanoparticles in hydrogels using microfluidics
-
Baah D, Vickers D, Hollinger A, Floyd-Smith T (2008) Patterned dispersion of nanoparticles in hydrogels using microfluidics. Mater Lett 62(23):3833-3835
-
(2008)
Mater Lett
, vol.62
, Issue.23
, pp. 3833-3835
-
-
Baah, D.1
Vickers, D.2
Hollinger, A.3
Floyd-Smith, T.4
-
3
-
-
4243111800
-
Serial dilution microchip for cytotoxicity test
-
Bang H, Lim SH, Lee YK, Chung S, Chung C, Han DC, Chang JK (2004) Serial dilution microchip for cytotoxicity test. J Micromech Microeng 14(8):1165-1170
-
(2004)
J Micromech Microeng
, vol.14
, Issue.8
, pp. 1165-1170
-
-
Bang, H.1
Lim, S.H.2
Lee, Y.K.3
Chung, S.4
Chung, C.5
Han, D.C.6
Chang, J.K.7
-
4
-
-
33846932052
-
Generation of complex concentration profiles in microchannels in a logarithmically small number of steps
-
DOI 10.1039/b610011b
-
Campbell K, Groisman A (2007) Generation of complex concentration profiles in microchannels in a logarithmically small number of steps. Lab Chip 7(2):264-272 (Pubitemid 46238550)
-
(2007)
Lab on a Chip - Miniaturisation for Chemistry and Biology
, vol.7
, Issue.2
, pp. 264-272
-
-
Campbell, K.1
Groisman, A.2
-
5
-
-
0344466691
-
Fabrication of the PDMS microchip for serially diluting sample with buffer
-
Chang JK, Bang H, Park SJ, Chung S, Chung C, Han DC (2003) Fabrication of the PDMS microchip for serially diluting sample with buffer. Microsyst Technol 9(8):555-558
-
(2003)
Microsyst Technol
, vol.9
, Issue.8
, pp. 555-558
-
-
Chang, J.K.1
Bang, H.2
Park, S.J.3
Chung, S.4
Chung, C.5
Han, D.C.6
-
6
-
-
58649091947
-
A multi-purpose microfluidic perfusion system with combinatorial choice of inputs, mixtures, gradient patterns, and flow rates
-
Cooksey GA, Sip CG, Folch A (2009) A multi-purpose microfluidic perfusion system with combinatorial choice of inputs, mixtures, gradient patterns, and flow rates. Lab Chip 9(3):417-426
-
(2009)
Lab Chip
, vol.9
, Issue.3
, pp. 417-426
-
-
Cooksey, G.A.1
Sip, C.G.2
Folch, A.3
-
7
-
-
34247593952
-
Digital microfluidics: Is a true lab-on-a-chip possible?
-
DOI 10.1007/s10404-007-0161-8
-
Fair RB (2007) Digital microfluidics: is a true lab-on-a-chip possible? Microfluid Nanofluid 3(3):245-281 (Pubitemid 46681552)
-
(2007)
Microfluidics and Nanofluidics
, vol.3
, Issue.3
, pp. 245-281
-
-
Fair, R.B.1
-
8
-
-
18744376054
-
An extracellular matrix microarray for probing cellular differentiation
-
DOI 10.1038/nmeth736
-
Flaim CJ, Chien S, Bhatia SN (2005) An extracellular matrix microarray for probing cellular differentiation. Nat Methods 2(2):119-125 (Pubitemid 41131033)
-
(2005)
Nature Methods
, vol.2
, Issue.2
, pp. 119-125
-
-
Flaim, C.J.1
Chien, S.2
Bhatia, S.N.3
-
9
-
-
0442312891
-
Synthesis and analysis of combinatorial libraries performed in an automated micro reactor system
-
DOI 10.1039/b302381h
-
Garcia-Egido E, Spikmans V, Wong SYF, Warrington BH (2003) Synthesis and analysis of combinatorial libraries performed in an automated micro reactor system. Lab Chip 3(2):73-76 (Pubitemid 41646563)
-
(2003)
Lab on a Chip - Miniaturisation for Chemistry and Biology
, vol.3
, Issue.2
, pp. 73-76
-
-
Garcia-Egido, E.1
Spikmans, V.2
Wong, S.Y.F.3
Warrington, B.H.4
-
10
-
-
67649382695
-
Generation of arbitrary monotonic concentration profiles by a serial dilution microfluidic network composed of microchannels with a high fluidic-resistance ratio
-
Hattori K, Sugiura S, Kanamori T (2009) Generation of arbitrary monotonic concentration profiles by a serial dilution microfluidic network composed of microchannels with a high fluidic-resistance ratio. Lab Chip 9(12):1763-1772
-
(2009)
Lab Chip
, vol.9
, Issue.12
, pp. 1763-1772
-
-
Hattori, K.1
Sugiura, S.2
Kanamori, T.3
-
11
-
-
78650334218
-
Microenvironment array chip for cell culture environment screening
-
Hattori K, Sugiura S, Kanamori T (2011) Microenvironment array chip for cell culture environment screening. Lab Chip 11(2): 212-214
-
(2011)
Lab Chip
, vol.11
, Issue.2
, pp. 212-214
-
-
Hattori, K.1
Sugiura, S.2
Kanamori, T.3
-
12
-
-
0038587441
-
Generating fixed concentration arrays in a microfluidic device
-
Holden MA, Kumar S, Castellana ET, Beskok A, Cremer PS (2003) Generating fixed concentration arrays in a microfluidic device. Sens Actuators B 92(1-2):199-207
-
(2003)
Sens Actuators B
, vol.92
, Issue.1-2
, pp. 199-207
-
-
Holden, M.A.1
Kumar, S.2
Castellana, E.T.3
Beskok, A.4
Cremer, P.S.5
-
13
-
-
33646746703
-
Universal microfluidic gradient generator
-
Irimia D, Geba DA, Toner M (2006) Universal microfluidic gradient generator. Anal Chem 78(10):3472-3477
-
(2006)
Anal Chem
, vol.78
, Issue.10
, pp. 3472-3477
-
-
Irimia, D.1
Geba, D.A.2
Toner, M.3
-
14
-
-
0035499521
-
Microfluidic arrays of fluid-fluid diffusional contacts as detection elements and combinatorial tools
-
DOI 10.1021/ac010502a
-
Ismagilov RF, Ng JMK, Kenis PJA, Whitesides GM (2001) Microfluidic arrays of fluid-fluid diffusional contacts as detection elements and combinatorial tools. Anal Chem 73(21): 5207-5213 (Pubitemid 33032238)
-
(2001)
Analytical Chemistry
, vol.73
, Issue.21
, pp. 5207-5213
-
-
Ismagilov, R.F.1
Ng, J.M.K.2
Kenis, P.J.A.3
Whitesides, G.M.4
-
15
-
-
0032748858
-
Microfluidic devices for electrokinetically driven parallel and serial mixing
-
Jacobson SC, McKnight TE, Ramsey JM (1999) Microfluidic devices for electrokinetically driven parallel and serial mixing. Anal Chem 71(20):4455-4459
-
(1999)
Anal Chem
, vol.71
, Issue.20
, pp. 4455-4459
-
-
Jacobson, S.C.1
McKnight, T.E.2
Ramsey, J.M.3
-
16
-
-
0036022527
-
Neutrophil chemotaxis in linear and complex gradients of interleukin-8 formed in a microfabricated device
-
DOI 10.1038/nbt712
-
Jeon NL, Baskaran H, Dertinger SKW, Whitesides GM, Van de Water L, Toner M (2002) Neutrophil chemotaxis in linear and complex gradients of interleukin-8 formed in a microfabricated device. Nat Biotechnol 20(8):826-830 (Pubitemid 34836761)
-
(2002)
Nature Biotechnology
, vol.20
, Issue.8
, pp. 826-830
-
-
Li Jeon, N.1
Baskaran, H.2
Dertinger, S.K.W.3
Whitesides, G.M.4
De Water, L.V.5
Toner, M.6
-
17
-
-
67849083164
-
Fabrication of a poly(dimethylsiloxane) membrane with well-defined through-holes for threedimensional microfluidic networks
-
Kang JH, Um E, Park JK (2009) Fabrication of a poly(dimethylsiloxane) membrane with well-defined through-holes for threedimensional microfluidic networks. J Micromech Microeng 19(4):045027
-
(2009)
J Micromech Microeng
, vol.19
, Issue.4
, pp. 045027
-
-
Kang, J.H.1
Um, E.2
Park, J.K.3
-
18
-
-
0037486064
-
Glass microchip with three-dimensional microchannel network for 2 9 2 parallel synthesis
-
DOI 10.1039/b208382p
-
Kikutani Y,Horiuchi T, Uchiyama K, Hisamoto H, TokeshiM,Kitamori T (2002) Glass microchip with three-dimensional microchannel network for 2 9 2 parallel synthesis. Lab Chip 2(4):188-192 (Pubitemid 37254477)
-
(2002)
Lab on a Chip - Miniaturisation for Chemistry and Biology
, vol.2
, Issue.4
, pp. 188-192
-
-
Kikutani, Y.1
Horiuchi, T.2
Uchiyama, K.3
Hisamoto, H.4
Tokeshi, M.5
Kitamori, T.6
-
19
-
-
23944432417
-
Continuous-flow chemical processing in three-dimensional microchannel network for on-chip integration of multiple reactions in a combinatorial mode
-
DOI 10.1002/qsar.200540002
-
Kikutani Y, Ueno M, Hisamoto H, Tokeshi M, Kitamori T (2005) Continuous-flow chemical processing in three-dimensional microchannel network for on-chip integration of multiple reactions in a combinatorial mode. QSAR Comb Sci 24(6): 742-757 (Pubitemid 41191996)
-
(2005)
QSAR and Combinatorial Science
, vol.24
, Issue.6
, pp. 742-757
-
-
Kikutani, Y.1
Ueno, M.2
Hisamoto, H.3
Tokeshi, M.4
Kitamori, T.5
-
20
-
-
0347565970
-
Strategies for the discovery of new catalysts with combinatorial chemistry
-
Kirsten G, Maier WF (2004) Strategies for the discovery of new catalysts with combinatorial chemistry. Appl Surf Sci 223(1-3): 87-101
-
(2004)
Appl Surf Sci
, vol.223
, Issue.1-3
, pp. 87-101
-
-
Kirsten, G.1
Maier, W.F.2
-
21
-
-
60649120060
-
Generalized serial dilution module for monotonic and arbitrary microfluidic gradient generators
-
Lee K, Kim C, Ahn B, Panchapakesan R, Full AR, Nordee L, Kang JY, Oh KW (2009) Generalized serial dilution module for monotonic and arbitrary microfluidic gradient generators. Lab Chip 9(5):709-717
-
(2009)
Lab Chip
, vol.9
, Issue.5
, pp. 709-717
-
-
Lee, K.1
Kim, C.2
Ahn, B.3
Panchapakesan, R.4
Full, A.R.5
Nordee, L.6
Kang, J.Y.7
Oh, K.W.8
-
22
-
-
77954763089
-
Microfluidic network-based combinatorial dilution device for high throughput screening and optimization
-
Lee K, Kim C, Jung G, Kim TS, Kang JY, Oh KW (2010a) Microfluidic network-based combinatorial dilution device for high throughput screening and optimization. Microfluid Nanofluid 8(5):677-685
-
(2010)
Microfluid Nanofluid
, vol.8
, Issue.5
, pp. 677-685
-
-
Lee, K.1
Kim, C.2
Jung, G.3
Kim, T.S.4
Kang, J.Y.5
Oh, K.W.6
-
23
-
-
77952891144
-
2-layer based microfluidic concentration generator by hybrid serial and volumetric dilutions
-
Lee K, Kim C, Kim Y, Jung K, Ahn B, Kang JY,OhKW(2010b) 2-layer based microfluidic concentration generator by hybrid serial and volumetric dilutions. Biomed Microdevices 12(2):297-309
-
(2010)
Biomed Microdevices
, vol.12
, Issue.2
, pp. 297-309
-
-
Lee, K.1
Kim, C.2
Kim, Y.3
Jung, K.4
Ahn, B.5
Kang, J.Y.6
Oh, K.W.7
-
24
-
-
67650488269
-
Synergistic drug combinations tend to improve therapeutically relevant selectivity
-
Lehar J, Krueger AS, Avery W, Heilbut AM, Johansen LM, Price ER, Rickles RJ, Short GF, Staunton JE, Jin XW, Lee MS, Zimmermann GR, Borisy AA (2009) Synergistic drug combinations tend to improve therapeutically relevant selectivity. Nat Biotechnol 27(7):659-666
-
(2009)
Nat Biotechnol
, vol.27
, Issue.7
, pp. 659-666
-
-
Lehar, J.1
Krueger, A.S.2
Avery, W.3
Heilbut, A.M.4
Johansen, L.M.5
Price, E.R.6
Rickles, R.J.7
Short, G.F.8
Staunton, J.E.9
Jin, X.W.10
Lee, M.S.11
Zimmermann, G.R.12
Borisy, A.A.13
-
25
-
-
34548091283
-
Combinatorial and highthroughput materials science
-
Maier WF, Stowe K, Sieg S (2007) Combinatorial and highthroughput materials science. Angew Chem Int Ed 46(32): 6016-6067
-
(2007)
Angew Chem Int Ed
, vol.46
, Issue.32
, pp. 6016-6067
-
-
Maier, W.F.1
Stowe, K.2
Sieg, S.3
-
26
-
-
77954591275
-
Simultaneous fabrication of PDMS through-holes for threedimensional microfluidic applications
-
Mosadegh B, Agarwal M, Torisawa YS, Takayama S (2010) Simultaneous fabrication of PDMS through-holes for threedimensional microfluidic applications. Lab Chip 10(15):1983-1986
-
(2010)
Lab Chip
, vol.10
, Issue.15
, pp. 1983-1986
-
-
Mosadegh, B.1
Agarwal, M.2
Torisawa, Y.S.3
Takayama, S.4
-
27
-
-
4344572516
-
Combinatorial mixing of microfluidic streams
-
DOI 10.1039/b314962e
-
Neils C, Tyree Z, Finlayson B, Folch A (2004) Combinatorial mixing of microfluidic streams. Lab Chip 4(4):342-350 (Pubitemid 39150236)
-
(2004)
Lab on a Chip - Miniaturisation for Chemistry and Biology
, vol.4
, Issue.4
, pp. 342-350
-
-
Neils, C.1
Tyree, Z.2
Finlayson, B.3
Folch, A.4
-
28
-
-
33750702858
-
Microfluidic serial dilution circuit
-
DOI 10.1021/ac0608265
-
Paegel BM, Grover WH, Skelley AM, Mathies RA, Joyce GF (2006) Microfluidic serial dilution circuit. Anal Chem 78(21): 7522-7527 (Pubitemid 44707661)
-
(2006)
Analytical Chemistry
, vol.78
, Issue.21
, pp. 7522-7527
-
-
Paegel, B.M.1
Grover, W.H.2
Skelley, A.M.3
Mathies, R.A.4
Joyce, G.F.5
-
29
-
-
33847114452
-
Optimisation methodologies and algorithms for research on catalysis employing high-throughput methods: Comparison using the Selox benchmark
-
DOI 10.2174/138620707779940901
-
Pereira SRM, Clerc F, Farrusseng D, van der Waal JC, Maschmeyer T (2007) Optimisation methodologies and algorithms for research on catalysis employing high-throughput methods: comparison using the selox benchmark. Comb Chem High Throughput Screen 10(2):149-159 (Pubitemid 46294167)
-
(2007)
Combinatorial Chemistry and High Throughput Screening
, vol.10
, Issue.2
, pp. 149-159
-
-
Pereira, S.R.M.1
Clerc, F.2
Farrusseng, D.3
Van Der Waal, J.C.4
Maschmeyer, T.5
-
30
-
-
18744407435
-
Microfluidic gradient-generating device for pharmacological profiling
-
DOI 10.1021/ac050218+
-
Pihl J, Sinclair J, Sahlin E, Karlsson M, Petterson F, Olofsson J, Orwar O (2005) Microfluidic gradient-generating device for pharmacological profiling. Anal Chem 77(13):3897-3903 (Pubitemid 40934250)
-
(2005)
Analytical Chemistry
, vol.77
, Issue.13
, pp. 3897-3903
-
-
Pihl, J.1
Sinclair, J.2
Sahlin, E.3
Karlsson, M.4
Petterson, F.5
Olofsson, J.6
Orwar, O.7
-
31
-
-
0036719852
-
Mitomycin C induces apoptosis and caspase-8 and -9 processing through a caspase-3 and Fas-independent pathway
-
DOI 10.1038/sj.cdd.4401062
-
Pirnia F, Schneider E, Betticher DC, Borner MM (2002) Mitomycin C induces apoptosis and caspase-8 and-9 processing through a caspase-3 and Fas-independent pathway. Cell Death Differ 9(9):905-914 (Pubitemid 35023606)
-
(2002)
Cell Death and Differentiation
, vol.9
, Issue.9
, pp. 905-914
-
-
Pirnia, F.1
Schneider, E.2
Betticher, D.C.3
Borner, M.M.4
-
32
-
-
0034326246
-
Mitomycin C resistance induced by TCF-3 overexpression in gastric cancer cell line MKN28 is associated with DT-diaphorase down-regulation
-
Sagara N, Katoh M (2000) Mitomycin C resistance induced by TCF-3 overexpression in gastric cancer cell line MKN28 is associated with DT-diaphorase down-regulation. Cancer Res 60(21): 5959-5962
-
(2000)
Cancer Res
, vol.60
, Issue.21
, pp. 5959-5962
-
-
Sagara, N.1
Katoh, M.2
-
33
-
-
67649335417
-
Microfluidic chip for combinatorial mixing and screening of assays
-
Schudel BR, Choi CJ, Cunningham BT, Kenis PJA (2009) Microfluidic chip for combinatorial mixing and screening of assays. Lab Chip 9(12):1676-1680
-
(2009)
Lab Chip
, vol.9
, Issue.12
, pp. 1676-1680
-
-
Schudel, B.R.1
Choi, C.J.2
Cunningham, B.T.3
Pja, K.4
-
34
-
-
23844484653
-
Optimizing drug delivery systems using systematic "design of experiments." Part II: Retrospect and prospects
-
DOI 10.1615/CritRevTherDrugCarrierSyst.v22.i3.10
-
Singh B, Dahiya M, Saharan P, Ahuja N (2005) Optimizing drug delivery systems using systematic "design of experiments". Part II: retrospect and prospects. Crit Rev Ther Drug Carrier Syst 22(3):215-293 (Pubitemid 41568171)
-
(2005)
Critical Reviews in Therapeutic Drug Carrier Systems
, vol.22
, Issue.3
, pp. 215-293
-
-
Singh, B.1
Dahiya, M.2
Saharan, V.3
Ahuja, N.4
-
35
-
-
48649091028
-
Pressure-driven perfusion culture microchamber array for a parallel drug cytotoxicity assay
-
Sugiura S, Edahiro J, Kikuchi K, Sumaru K, Kanamori T (2008) Pressure-driven perfusion culture microchamber array for a parallel drug cytotoxicity assay. Biotechnol Bioeng 100(6): 1156-1165
-
(2008)
Biotechnol Bioeng
, vol.100
, Issue.6
, pp. 1156-1165
-
-
Sugiura, S.1
Edahiro, J.2
Kikuchi, K.3
Sumaru, K.4
Kanamori, T.5
-
36
-
-
77953621476
-
Interfacing microfluidics to LDI-MS by automatic robotic spotting
-
Tsao CW, Tao S, Chen CF, Liu JK, DeVoe DL (2010) Interfacing microfluidics to LDI-MS by automatic robotic spotting. Microfluid Nanofluid 8(6):777-787
-
(2010)
Microfluid Nanofluid
, vol.8
, Issue.6
, pp. 777-787
-
-
Tsao, C.W.1
Tao, S.2
Chen, C.F.3
Liu, J.K.4
Devoe, D.L.5
-
37
-
-
2442502550
-
Application of statistical 'design of experiments' methods in drug discovery
-
DOI 10.1016/S1359-6446(04)03086-7, PII S1359644604030867
-
Tye H (2004) Application of statistical 'design of experiments' methods in drug discovery. Drug Discov Today 9(11):485-491 (Pubitemid 38626085)
-
(2004)
Drug Discovery Today
, vol.9
, Issue.11
, pp. 485-491
-
-
Tye, H.1
-
38
-
-
52049121805
-
Combinatorial and high-throughput methods in macromolecular materials research and development
-
Webster DC (2008) Combinatorial and high-throughput methods in macromolecular materials research and development. Macromol Chem Phys 209(3):237-246
-
(2008)
Macromol Chem Phys
, vol.209
, Issue.3
, pp. 237-246
-
-
Webster, D.C.1
-
41
-
-
67349185120
-
Integrated microfluidic devices for combinatorial cell-based assays
-
Yu ZTF, Kamei KI, Takahashi H, Shu CJ, Wang XP, He GW, Silverman R, Radu CG, Witte ON, Lee KB, Tseng HR (2009) Integrated microfluidic devices for combinatorial cell-based assays. Biomed Microdevices 11(3):547-555
-
(2009)
Biomed Microdevices
, vol.11
, Issue.3
, pp. 547-555
-
-
Ztf, Y.1
Kamei, K.I.2
Takahashi, H.3
Shu, C.J.4
Wang, X.P.5
He, G.W.6
Silverman, R.7
Radu, C.G.8
Witte, O.N.9
Lee, K.B.10
Tseng, H.R.11
|