High-dose oral fluconazole therapy effective for cutaneous leishmaniasis due to leishmania (vianna) Braziliensis

Clinical Infectious Diseases

Volumn 53, Issue 7, 2011, Pages 693-695

  Sousa, Anastácio Q ^a   Frutuoso, Mércia S ^b,c   Moraes, Elisabete A ^d   Pearson, Richard D ^e   Pompeu, Margarida M L ^c  

^a Rua Nestor Barbosa   (Brazil)

^b Christus School of Medicine   (United States)

^c University School of Medicine   (United States)

^d FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^e UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUCONAZOLE;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CLINICAL ARTICLE; DRUG DOSE ESCALATION; DRUG EFFICACY; DRUG MEGADOSE; FEMALE; HUMAN; LEISHMANIA BRAZILIENSIS; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SKIN LEISHMANIASIS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIPROTOZOAL AGENTS; CHILD; CHILD, PRESCHOOL; FEMALE; FLUCONAZOLE; HUMANS; LEISHMANIA BRAZILIENSIS; LEISHMANIASIS, CUTANEOUS; MALE; MIDDLE AGED; TREATMENT OUTCOME; YOUNG ADULT;

EID: 80052499066     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/cir496     Document Type: Article

References (12)

1. World Health Organization. Report of the fifth consultative meeting on Leishmania/HIV Coinfection-Word Health Organization. Addis Ababa, Ethiopia, 2007: 20-2. Available at: http://www.who.int/leishmaniasis/resources/ Leishmaniasis=hiv=coinfection5.pdf. Accessed 13 May 2011.
2. Sousa AQ, Parise ME, Pompeu MM, et al. Bubonic leishmaniasis: a common manifestation of Leishmania (Viannia) braziliensis infection in Ceara, Brazil. Am J TropMed Hyg 1995; 53:380-5.
3. Harms G, Fraga F, Batroff B, Oliveira F, Feldmeier H. Cutaneous leishmaniasis associated with extensive lymphadenopathy during an epidemic in Ceara State, northeast Brazil. Acta Trop 2005; 93: 303-10. (Pubitemid 40348834)
4. Marsden PD. Pentavalent antimonials: old drugs for new diseases. Rev Soc Bras Med Trop 1985; 18:187-98.
5. Beach DH, Goad LJ, Holz GG Jr. Effects of antimycotic azoles on growth and sterol biosynthesis of Leishmania promastigotes. Mol Biochem Parasitol 1988; 31:149-62.
6. Albanese G, Giorgetti P, Santagostino L, Crippa D, Sala G. Cutaneous leishmaniasis: treatment with itraconazole. Arch Dermatol Res 1989; 125:1540-2.
7. Alrajhi AA, Ibrahim EA, De Vol EB, Khairat M, Faris RM, Maguire JH. Fluconazole for the treatment of cutaneous leishmaniasis caused by Leishmania major. N Engl J Med 2002; 346:891-5. (Pubitemid 34984637)
8. Morizot G, Delgiudice P, Caumes E, et al. Healing of Old World cutaneous leishmaniasis in travelers treated with fluconazole: drug effect or spontaneous evolution? Am J Trop Med Hyg 2007; 76:48-52. (Pubitemid 351627801)
9. Como JA, Dismukes WE. Oral azole drugs as systemic antifungal therapy. N Engl J Med 1994; 330:263-72. (Pubitemid 24034139)
10. Malik A. Origin of drugs in current use: the Diflucan story, 2001. Available at: http://www.world-offungi.org/Mostly=Medical/Abrar=Malik/Abrar= Malik.htm. Accessed 24 September 2010.
11. Emad M, Hayati F, Fallahzadeh MK, Namazi MR. Superior efficacy of oral fluconazole 400 mg daily versus oral fluconazole 200 mg daily in the treatment of cutaneous Leishmania major infection: a randomized clinical trial. J Am Acad Dermatol 2011; 64:606-8.
12. Menichetti F, Fiorio M, Tosti A, et al. High-dose fluconazole therapy for cryptococcal meningitis in patients with AIDS. Clin Infect Dis 1996; 22:838-40. (Pubitemid 26255605)