Importance of residual myocardial ischemia after intervention in the genesis of cardiovascular events among patients with chronic coronary artery disease

Current Cardiology Reports

Volumn 13, Issue 4, 2011, Pages 280-286

  Shaw, Leslee J ^a   Hachamovitch, Rory ^b   Min, James ^c   Berman, Daniel S ^c  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

Cardiovascular events; Chronic coronary artery disease; Myocardial ischemia

Indexed keywords

ARTICLE; CORONARY ARTERY DISEASE; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST; DISEASE SEVERITY; EVIDENCE BASED MEDICINE; EXERCISE TEST; HEART DEATH; HEART MUSCLE ISCHEMIA; HEART MUSCLE REVASCULARIZATION; HEART PERFUSION; HUMAN; MEDICAL DECISION MAKING; RANDOMIZED CONTROLLED TRIAL (TOPIC); SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SURVIVAL; TREATMENT RESPONSE;

CHRONIC DISEASE; CORONARY ARTERY DISEASE; DISEASE PROGRESSION; EXERCISE TEST; HEALTH STATUS INDICATORS; HUMANS; MYOCARDIAL ISCHEMIA; MYOCARDIAL PERFUSION IMAGING; PROGNOSIS; REST; SEVERITY OF ILLNESS INDEX; SURVIVAL ANALYSIS; TIME FACTORS; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 80052475479     PISSN: 15233782     EISSN: 15343170     Source Type: Journal    
DOI: 10.1007/s11886-011-0193-2     Document Type: Article

References (29)

1. Boden WE, O'Rourke RA, Teo KK, Hartigan PM, Maron DJ, Kostuk WJ, et al. Optimal medical therapy with or without pci for stable coronary disease. N Engl J Med. 2007;356:1503-16. (Pubitemid 46588415)
2. Frye RL, August P, Brooks MM, Hardison RM, Kelsey SF, MacGregor JM, et al. A randomized trial of therapies for type 2 diabetes and coronary artery disease. N Engl J Med. 2009;360:2503-15.
3. Shaw LJ, Berman DS, Maron DJ, Mancini GB, Hayes SW, Hartigan PM, Weintraub WS, O'Rourke RA, Dada M, Spertus JA, Chaitman BR, Friedman J, Slomka P, Heller GV, Germano G, Gosselin G, Berger P, Kostuk WJ, Schwartz RG, Knudtson M, Veledar E, Bates ER, McCallister B, Teo KK, Boden WE. Optimal medical therapy with or without percutaneous coronary intervention to reduce ischemic burden: Results from the clinical outcomes utilizing revascularization and aggressive drug evaluation (COURAGE) trial nuclear substudy. Circulation. 2008;117:1283-1291. This paper reports the results from the COURAGE nuclear substudy in 314 patients who underwent serial testing for the purposes of defining the efficacy of randomized treatments for reducing ischemia. The results of this substudy reveal an advantage with PCI plus optimal medical therapy in terms of ischemia reduction when compared with optimal medical therapy alone. (Pubitemid 351365675)
4. Shaw LJ, Iskandrian AE. Prognostic value of gated myocardial perfusion spect. J Nucl Cardiol. 2004;11:171-85. (Pubitemid 38949912)
5. Berman DS, Hachamovitch R, Kiat H, Cohen I, Cabico JA, Wang FP, et al. Incremental value of prognostic testing in patients with known or suspected ischemic heart disease: A basis for optimal utilization of exercise technetium-99m sestamibi myocardial perfusion single-photon emission computed tomography. J Am Coll Cardiol. 1995;26:639-47.
6. Hachamovitch R, Berman DS, Kiat H, Bairey-Merz N, Cohen I, Cabico JA, et al. Gender-related differences in clinical management after exercise nuclear testing. J Am Coll Cardiol. 1995;26:1457-64.
7. Hachamovitch R, Berman DS, Kiat H, Bairey CN, Cohen I, Cabico A, et al. Effective risk stratification using exercise myocardial perfusion spect in women: gender-related differences in prognostic nuclear testing. J Am Coll Cardiol. 1996;28:34-44. (Pubitemid 26266620)
8. Hachamovitch R, Berman DS, Shaw LJ, Kiat H, Cohen I, Cabico JA, et al. Incremental prognostic value of myocardial perfusion single photon emission computed tomography for the prediction of cardiac death: Differential stratification for risk of cardiac death and myocardial infarction. Circulation. 1998;97:535-43. (Pubitemid 28090682)
9. Berman DS, Kang X, Hayes SW, Friedman JD, Cohen I, Abidov A, et al. Adenosine myocardial perfusion single-photon emission computed tomography in women compared with men. Impact of diabetes mellitus on incremental prognostic value and effect on patient management. J Am Coll Cardiol. 2003;41:1125-33. (Pubitemid 36384899)
10. Hachamovitch R, Hayes SW, Friedman JD, Cohen I, Berman DS. Comparison of the short-term survival benefit associated with revascularization compared with medical therapy in patients with no prior coronary artery disease undergoing stress myocardial perfusion single photon emission computed tomography. Circulation. 2003;107:2900-7.
11. Hachamovitch R, Hayes S, Friedman JD, Cohen I, Shaw LJ, Germano G, et al. Determinants of risk and its temporal variation in patients with normal stress myocardial perfusion scans: what is the warranty period of a normal scan? J Am Coll Cardiol. 2003;41:1329-40. (Pubitemid 36438995)
12. Hachamovitch R, Rozanski A, Hayes SW, Thomson LE, Germano G, Friedman JD, et al. Predicting therapeutic benefit from myocardial revascularization procedures: Are measurements of both resting left ventricular ejection fraction and stress-induced myocardial ischemia necessary? J Nucl Cardiol. 2006;13:768-78. (Pubitemid 44913652)
13. Hachamovitch R, Rozanski A, Shaw LJ, Stone GW, Thomson LE, Friedman JD, Hayes SW, Cohen I, Germano G, Berman DS. Impact of ischaemia and scar on the therapeutic benefit derived from myocardial revascularization vs. Medical therapy among patients undergoing stress-rest myocardial perfusion scintigraphy. Eur Heart J. 2011. This paper highlights the importance of scarred myocardium in determining therapeutic benefit from revascularization.
14. Sorajja P, Chareonthaitawee P, Rajagopalan N, Miller TD, Frye RL, Hodge DO, et al. Improved survival in asymptomatic diabetic patients with high-risk spect imaging treated with coronary artery bypass grafting. Circulation. 2005;112:I311-6. (Pubitemid 41266692)
15. Hachamovitch R, Kang X, Amanullah AM, Abidov A, Hayes SW, Friedman JD, et al. Prognostic implications of myocardial perfusion single-photon emission computed tomography in the elderly. Circulation. 2009;120:2197-206.
16. Shaw LJ, Heller GV, Casperson P, Miranda-Peats R, Slomka P, Friedman J, et al. Gated myocardial perfusion single photon emission computed tomography in the clinical outcomes utilizing revascularization and aggressive drug evaluation (courage) trial, veterans administration cooperative study no. 424. J Nucl Cardiol. 2006;13:685-98. (Pubitemid 44375494)
17. Mahmarian JJ, Fenimore NL, Marks GF, Francis MJ, Morales- Ballejo H, Verani MS, et al. Transdermal nitroglycerin patch therapy reduces the extent of exercise-induced myocardial ischemia: Results of a double-blind, placebo-controlled trial using quantitative thallium-201 tomography. J Am Coll Cardiol. 1994;24:25-32. (Pubitemid 24202772)
18. Bourassa MG, Pepine CJ, Forman SA, Rogers WJ, Dyrda I, Stone PH, et al. Asymptomatic cardiac ischemia pilot (acip) study: Effects of coronary angioplasty and coronary artery bypass graft surgery on recurrent angina and ischemia. The acip investigators. J Am Coll Cardiol. 1995;26:606-14.
19. Pratt CM, Mahmarian JJ, Morales-Ballejo H, Casareto R, Moye LA. Design of a randomized, placebo-controlled multicenter trial on the long-term effects of intermittent transdermal nitroglycerin on left ventricular remodeling after acute myocardial infarction. Transdermal nitroglycerin investigators group. Am J Cardiol. 1998;81:719-24. (Pubitemid 28146446)
20. Mahmarian JJ, Moye LA, Chinoy DA, Sequeira RF, Habib GB, Henry WJ, et al. Transdermal nitroglycerin patch therapy improves left ventricular function and prevents remodeling after acute myocardial infarction: results of a multicenter prospective randomized, double-blind, placebo-controlled trial. Circulation. 1998;97:2017-24. (Pubitemid 28243663)
21. Dakik HA, Kleiman NS, Farmer JA, He ZX, Wendt JA, Pratt CM, et al. Intensive medical therapy versus coronary angioplasty for suppression of myocardial ischemia in survivors of acute myocardial infarction: a prospective, randomized pilot study. Circulation. 1998;98:2017-23. (Pubitemid 28512226)
22. Mahmarian JJ, Dakik HA, Filipchuk NG, Shaw LJ, Iskander SS, Ruddy TD, et al. An initial strategy of intensive medical therapy is comparable to that of coronary revascularization for suppression of scintigraphic ischemia in high-risk but stable survivors of acute myocardial infarction. J Am Coll Cardiol. 2006;48:2458-67. (Pubitemid 44881230)
23. Schwartz RG, Pearson TA, Kalaria VG, Mackin ML, Williford DJ, Awasthi A, et al. Prospective serial evaluation of myocardial perfusion and lipids during the first six months of pravastatin therapy: coronary artery disease regression single photon emission computed tomography monitoring trial. J Am Coll Cardiol. 2003;42:600-10. (Pubitemid 37000172)
24. Shaw L, Cerqueira M, Brooks MM, Sansing VV, Beller GA, Pop-Busui R, et al. Impact of left ventricular function and the extent of ischemia and scar by stress myocardial perfusion imaging on prognosis and therapeutic risk reduction in diabetic patients with coronary artery disease: results from the bypass angioplasty revascularization investigation 2d (bari 2d) trial. Circulation. 2010.
25. Parisi AF, Hartigan PM, Folland ED. Evaluation of exercise thallium scintigraphy versus exercise electrocardiography in predicting survival outcomes and morbid cardiac events in patients with single- and double-vessel disease. Findings from the angioplasty compared to medicine (acme) study. J Am Coll Cardiol. 1997;30:1256-63. (Pubitemid 27501443)
26. Gibbons RJ, Abrams J, Chatterjee K, Daley J, Deedwania PC, Douglas JS, et al. ACC/AHA 2002 guideline update for the management of patients with chronic stable angina-summary article: a report of the american college of cardiology/american heart association task force on practice guidelines (committee on the management of patients with chronic stable angina). J Am Coll Cardiol. 2003;41:159-68. (Pubitemid 36044419)
27. Hendel RC, Berman DS, Di Carli MF, Heidenreich PA, Henkin RE, Pellikka PA, et al. Appropriate use criteria for cardiac radionuclide imaging: a report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, the American Society of Nuclear Cardiology, the American College of Radiology, the American Heart Association, the American Society of Echocardiography, the Society of Cardiovascular Computed Tomography, the Society for Cardiovascular Magnetic Resonance, and the Society of Nuclear Medicine. J Am Coll Cardiol. 2009;53:2201-29.
28. Tonino PA, De Bruyne B, Pijls NH, Siebert U, Ikeno F, van't Veer M, et al. Fractional flow reserve versus angiography for guiding percutaneous coronary intervention. N Engl JMed. 2009;360:213-24.
29. Tonino PA, Fearon WF, De Bruyne B, Oldroyd KG, Leesar MA, Ver Lee PN. Angiographic versus functional severity of coronary artery stenoses in the fame study fractional flow reserve versus angiography in multivessel evaluation. J Am Coll Cardiol. 2010;55:2816-21.