Unrecognized fatalities related to colchicine in hospitalized patients

Clinical Toxicology

Volumn 49, Issue 7, 2011, Pages 648-652

  Mullins, Michael ^a   Cannarozzi, Amanda A ^a   Bailey, Thomas C ^a   Ranganathan, Prabha ^b  

^a WASHINGTON UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adverse event; Colchicine; Fatal outcome

Indexed keywords

AMIODARONE; ANTINEOPLASTIC AGENT; CLARITHROMYCIN; COLCHICINE; CYCLOSPORIN; DILTIAZEM; ERYTHROMYCIN; INDINAVIR; ITRACONAZOLE; KETOCONAZOLE; NELFINAVIR; NICARDIPINE; PROPAFENONE; QUINIDINE; RITONAVIR; SAQUINAVIR; TACROLIMUS; TAMOXIFEN; VERAPAMIL;

ADULT; AGED; CLINICAL ARTICLE; CLINICAL FEATURE; CREATININE CLEARANCE; DRUG ANTAGONISM; DRUG FATALITY; DRUG INTOXICATION; FEMALE; HOSPITAL PATIENT; HUMAN; MALE; REVIEW; TERTIARY HEALTH CARE;

AGED; AGED, 80 AND OVER; COLCHICINE; DRUG DOSAGE CALCULATIONS; DRUG INTERACTIONS; FEMALE; GOUT SUPPRESSANTS; GUIDELINE ADHERENCE; HOSPITAL MORTALITY; HOSPITALIZATION; HUMANS; INPATIENTS; MALE; MEDICATION ERRORS; MISSOURI; OVERDOSE; PRACTICE GUIDELINES AS TOPIC; RETROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; TIME FACTORS;

EID: 80052465323     PISSN: 15563650     EISSN: 15569519     Source Type: Journal    
DOI: 10.3109/15563650.2011.589844     Document Type: Review

References (12)

1. Ebadi M. Pharmacodynamic Basis of Herbal Medicine. 2nd ed. Boca Raton: CRC Press; 2007: 275-276.
2. Katzung B. Basic and Clinical Pharmacology. 9th ed. New York: McGraw-Hill; 2004: 596-597.
3. Bismuth C, Gaultier M, Conso F. Medullary aplasia after acute colchicine poisoning. Nouv Presse Med 1977; 6:1625-1629. (Pubitemid 8084487)
4. Finkelstein Y, Aks SE, Hutson JR, Juurlink DN, Nguyen P, Dubinov- Raz G, et al. Colchicine poisoning: the dark side of an ancient drug. Clin Toxicol 2010; 48:407-414.
5. Cockcroft DW, Gault MH. Prediction of creatinine clearance from creatinine. Nephron 1976; 16:31-41.
6. The use of the WHO-UMC system for standardized case causal ity assessment. www.who-umc.org/graphics/4409.pdf. Accessed 6 October 2010 .
7. FDA. Information for Healthcare Professionals: New Safety Information for Colchicine (marketed as Colcrys) Drugs/DrugSafety/ PostmarketDrugSafetyInformationforPatientsand Providers/ DrugSafetyInformationforHeathcareProfessionals/ucm 174315.htm. Accessed 10 March 2011.
8. Bonnel RA, Villalba ML, Karwoski CB, Beitz J. Deaths associated with inappropriate intravenous colchicine administration. J Emerg Med 2002; 22:385-387. (Pubitemid 34756312)
9. FDA. SafetyAlertsforHumanMedicalProducts/ucm110232.htm. Accessed10 March 2011.
10. Eleftheriou G, Bacis G, Fiocchi R, Sebastiano R. Colchicine-induced toxicity in a heart transplant patient with chronic renal failure. Clin Toxicol 2008; 46:827-830.
11. Cheng VCC, Ho PL, Yuen KY. Two probable cases of serious drug interaction between clarithromycin and colchicine. South Med J 2005; 98:811-813. (Pubitemid 41243680)
12. Hung IFN, Wu AKL, Cheng VCC, Tang BSF, To KW, Yeung CK, et al. Fatal interaction between clarithromycin and colchicine in patients with renal insuffi ciency: a retrospective study. Clin Infect Dis 2005; 41:291-300. (Pubitemid 41022103)