Effects of nano-hydroxyapatite content on bone formation in nano-hydroxyapatite-collagen composite membrane with BMP-2 application

Nano Biomedicine

Volumn 1, Issue 2, 2009, Pages 159-166

  Tenkumo, Taichi ^a   Sugaya, Tsutomu ^a   Kawanami, Masamitsu ^a   Watari, Fumio ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

BMP 2; Bone formation; Hydroxyapatite; In vivo; Nanomaterials

Indexed keywords

BMP-2; BONE FORMATION; ECTOPIC BONES; IN VIVO; MALE RATS; MIXING RATIOS; NANO-HYDROXYAPATITE; NANO-SIZE; SUBCUTANEOUS TISSUES;

BONE; CALCIUM PHOSPHATE; COLLAGEN; HYDROXYAPATITE; NANOCOMPOSITES; TISSUE;

APATITE;

EID: 80052461627     PISSN: 18835198     EISSN: 21854734     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Urist MR, Strates BS:Bone morphogenetic protein. J Dent Res 1971;50:1392-1406.
2. Wozney JM:Bone Morphogenetic Proteins. Prog Growth Factor Res 1989;1:267-280.
3. Ibe K, Miyaji H, Sugaya T, Kawanami M. Periodontal regeneration by BMP-2 application to root dentin surface. Nippon Shishubyo Gakkai Kaishi 2004;46:278-287.
4. Isizuka R, Miyaji H, Sugaya T, Kawanami M. Periodontal regeneration by BMP-2 solution and collagen hydrogel application to root dentin surface. Nippon Shishubyo Gakkai Kaishi 2006;48:255-266.
5. Wikesjö UM, Guglielmoni P, Promsudthi A, Cho KS, Trombelli L, Selvig KA, Jin L, Wozney JM. Periodontal repair in dogs: effect of rhBMP-2 concentration on regeneration of alveolar bone and periodontal attachment. J Clin Periodontol 1999;26:392-400.
6. Miyaji H, Sugaya T, Miyamoto T, Kato K., Kato H: Hard tissue formation on dentin surfaces applied with recombinant human bone morphogenetic protein-2 in the connective tissue of the palate. J Periodontol Res 2002;37:204-209.
7. Bernhardt A, Lode A, Boxberger S, Pompe W, Gelinsky M. Mineralised collagen-an artificial, extracellular bone matrix-improves osteogenic differentiation of bone marrow stromal cells. J Mater Sci Mater Med 2008;19:269-275.
8. Schliephake H, Tavassol F, Gelinsky M, Dard M, Sewing A, Pompe W. Use of a mineralized collagen membrane to enhance repair of calvarial defects in rats.Clin Oral Implants Res 2004;15:112-118. (Pubitemid 38686952)
9. Bradt JH, Mertig M, Teresiak A, Pompe W. Biomimetic mineralization of collagen by combined fibril assembly and calcium phosphate formation. Chemistry of Materials 1999;11:2694-2701. (Pubitemid 129692345)
10. Matsumoto T, Okazaki M, Inoue M, Hamada Y, Taira M, Takahashi J. Crystallinity and solubility characteristics of hydroxyapatite adsorbed amino acid. Biomaterials 2002; 23:2241-2247. (Pubitemid 34226584)
11. Maeda H, Sano A, Fujioka K. Controlled release of rhBMP-2 from collagen minipellet and the relationship between release profile and ectopic bone formation. Int J Pharm 2004;275:109-122. (Pubitemid 38481524)
12. Dong X, Wang Q, Wu T, Pan H. Understanding adsorption-desorption dynamics of BMP-2 on hydroxyapatite (001) surface. Biophys J 2007;93:750-759. (Pubitemid 47219770)
13. Matsumoto T, Okazaki M, Inoue M, Yamaguchi S, Kusunose T, Toyonaga T, Hamada Y, Takahashi J. Hydroxyapatite particles as a controlled release carrier of protein. Biomaterials 2004;25:3807-3812. (Pubitemid 38327069)
14. Yamamoto M, Takahashi Y, Tabata Y. Controlled release by biodegradable hydrogels enhances the ectopic bone formation of bone morphogenetic protein. biomaterials 2003;24:4375-4383. (Pubitemid 36960135)
15. Yokoyama A, Gelinsky M, Kawasaki T, Kohgo T, König U, Pompe W, Watari F. Biomimetic porous scaffolds with high elasticity made from mineralized collagen-an animal study. J Biomed Mater Res B Appl Biomater 2005;75:464-472. (Pubitemid 41609569)
16. Oonishi H, Hench LL, Wilson J, Sugihara F, Tsuji E, Kushitani S, Iwaki H. Comparative bone growth behavior in granules of bioceramic materials of various sizes. J Biomed Mater Res 1999;44:31-43. (Pubitemid 28544083)
17. Parfitt AM. The mechanism of coupling: a role for the vasculature. Bone 2000;26:319-323.
18. Silver IA, Murrills RJ, Etherington DJ. Microelectrode studies on the acid microenvironment beneath adherent macrophages and osteoclasts. Exp Cell Res 1988; 175:266-276.
19. Melita M, Dvorak Daniela Riccardi. Ca2+ as an extracellular signal in bone. Cell calcium 2004;35:249-255.
20. Dvorak MM, Siddiqua A, Ward DT, Carter DH, Dallas SL, Nemeth EF, Riccardi D. Physiological changes in extracellular calcium concentration directly control osteoblast function in the absence of calciotropic hormones. Proc Natl Acad Sci U S A 2004;101:5140-5145. (Pubitemid 38469215)
21. Fukuchi N, Akao M, Aoki H. Solubility of hydroxyapatite microcrystals and morphological changes in macrophages. Shika Zairyo Kikai 1996;15:20-28.
22. Monchau F, Lefèvre A, Descamps M, Belquin-myrdycz A, Laffargue P, Hildebrand HF. In vitro studies of human and rat osteoclast activity on hydroxyapatite, beta-tricalcium phosphate, calcium carbonate. Biomol Eng 2002;19:143-152.
23. Kuboki Y, Jin Q, Takita H. Geometry of carriers controlling phenotypic expression in BMP-induced osteogenesis and chondrogenesis. J Bone Joint Surg Am 2001;83:105-115.