Clopidogrel protects from cell apoptosis and oxidative damage in a mouse model of renal ischaemia-reperfusion injury

Journal of Pathology

Volumn 225, Issue 2, 2011, Pages 265-275

  Hu, Honglin ^a,b   Batteux, Frédéric ^a   Chéreau, Christiane ^a   Kavian, Niloufar ^a   Marut, Wioleta ^a   Gobeaux, Camille ^c   Borderie, Didier ^c   Dinh Xuan, Anh Tuan ^c   Weill, Bernard ^a   Nicco, Carole ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b NANCHANG UNIVERSITY   (China)

^c AP HP ^*  (France)

Author keywords

apoptosis; clopidogrel; ischaemia reperfusion injury; kidney; oxidant damage

Indexed keywords

CASPASE 3; CASPASE 8; CATALASE; CLOPIDOGREL; CREATININE; FIBRINOGEN RECEPTOR; GLUTATHIONE; NITROGEN; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; SUPEROXIDE DISMUTASE; UREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVITY; GRANULOCYTE; HISTOPATHOLOGY; KIDNEY FUNCTION; KIDNEY ISCHEMIA; KIDNEY TUBULE DAMAGE; MALE; MONOCYTE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RENAL PROTECTION; REPERFUSION INJURY; SCORING SYSTEM; SINGLE DRUG DOSE; SURVIVAL RATE; UPREGULATION; UREA NITROGEN BLOOD LEVEL; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; DISEASE MODELS, ANIMAL; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOBLOTTING; IN SITU NICK-END LABELING; KIDNEY; MALE; MICE; MICE, INBRED BALB C; OXIDATIVE STRESS; PURINERGIC P2Y RECEPTOR ANTAGONISTS; REPERFUSION INJURY; TICLOPIDINE;

EID: 80052444820     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2916     Document Type: Article

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