Odor detection threshold, but not odor identification, is impaired in children with autism

European Child and Adolescent Psychiatry

Volumn 20, Issue 7, 2011, Pages 333-340

  Dudova, Iva ^a   Vodicka, Jan ^b   Havlovicova, Marketa ^a   Sedlacek, Zdenek ^a   Urbanek, Tomas ^c   Hrdlicka, Michal ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

^b UNIVERSITY OF PARDUBICE   (Czech Republic)

^c INSTITUTE OF MATHEMATICS   (Czech Republic)

Author keywords

Autism spectrum disorders; Odor identification; Odor threshold; Olfactory; Sensory abnormalities; Sniffin' Sticks

Indexed keywords

AGE; ARTICLE; ASPERGER SYNDROME; AUTISM; CHILD; CLINICAL ARTICLE; CLOVE; CONTROLLED STUDY; FEMALE; FUNCTION TEST; GENDER; HUMAN; MALE; ODOR; OLFACTORY DISCRIMINATION; ORANGE (FRUIT); PERCEPTIVE THRESHOLD; SCHOOL CHILD; SCORING SYSTEM; SMELLING; SNIFFIN STICK TEST; SNIFFING;

ADOLESCENT; AGE FACTORS; ASPERGER SYNDROME; AUTISTIC DISORDER; CHILD; FEMALE; HUMANS; MALE; ODORS; OLFACTION DISORDERS; OLFACTORY PERCEPTION; PATIENT SELECTION; PSYCHIATRIC STATUS RATING SCALES; RESEARCH DESIGN; SENSORY THRESHOLDS; SEVERITY OF ILLNESS INDEX; SMELL;

EID: 80052434974     PISSN: 10188827     EISSN: 1435165X     Source Type: Journal    
DOI: 10.1007/s00787-011-0177-1     Document Type: Article

References (39)

1. RI Mesholam PJ Moberg RN Mahr RL Doty 1998 Olfaction in neurodegenerative disease. A meta-analysis of olfactory functioning in Alzheimer's and Parkinson's diseases Arch Neurol 55 84 90 9443714 10.1001/archneur.55.1.84 1:STN:280:DyaK1c7gtl2msw%3D%3D (Pubitemid 28139109)
2. C Hawkes 2003 Olfaction in neurodegenerative disorder Mov Disord 18 364 372 12671941 10.1002/mds.10379 (Pubitemid 36527276)
3. Brewer WJ, Castle D, Ch Pantelis (2006) Olfaction and the brain. Cambridge University Press, New York
4. O Suchowersky S Reich J Perlmutter T Zesiewicz G Gronseth WJ Weiner 2006 Practice parameter: diagnosis and prognosis of new onset Parkinson disease (an-evidence based review) Neurology 66 968 975 16606907 10.1212/01.wnl. 0000215437.80053.d0 1:STN:280:DC%2BD283gtVSksw%3D%3D (Pubitemid 44044778)
5. PJ Moberg R Agrin RE Gur RC Gur BI Turetsky RL Doty 1999 Olfactory dysfunction in schizophrenia: a qualitative and quantitative review Neuropsychopharmacol 21 325 340 10.1016/S0893-133X(99)00019-6 1:STN:280:DyaK1MzosF2rsg%3D%3D (Pubitemid 29333071)
6. SR Leekam C Nieto SJ Libby L Wing J Gould 2007 Describing the sensory abnormalities of children and adults with autism J Autism Dev Disord 37 894 910 17016677 10.1007/s10803-006-0218-7 (Pubitemid 46790788)
7. MA Kientz W Dunn 1997 A comparison of the performance of children with and without autism on the sensory profile Am J Occup Ther 51 530 537 9242859 1:STN:280:DyaK2szos1Oluw%3D%3D (Pubitemid 127453151)
8. SJ Rogers S Hepburn E Wehner 2003 Parent reports of sensory symptoms in toddlers with autism and those with other developmental disorders J Autism Dev Disord 33 631 642 14714932 10.1023/B:JADD.0000006000.38991.a7 (Pubitemid 38036320)
9. GT Baranek FJ David MD Poe WL Stone LR Watson 2006 Sensory experiences questionnaire: discriminating sensory features in young children with autism, developmental delays, and typical development J Child Psychol Psychiatry 47 591 601 16712636 10.1111/j.1469-7610.2005.01546.x (Pubitemid 43744790)
10. JK Kern CR Garver MH Trivedi BD Grannemann AA Andrews JS Savla DG Johnson JA Mehta JL Schroeder 2006 The pattern of sensory processing abnormalities in autism Autism 10 480 494 16940314 10.1177/1362361306066564 (Pubitemid 44263921)
11. RL Watling J Deitz O White 2001 Comparison of sensory profile scores of young children with and without autism spectrum disorder Am J Occup Ther 55 416 423 11723986 10.5014/ajot.55.4.416 1:STN:280:DC%2BD3MnnvVWquw%3D%3D (Pubitemid 33602573)
12. AE Lane RL Young AE Baker MT Angley 2010 Sensory processing subtypes in autism: association with adaptive behavior J Autism Dev Disord 40 112 122 19644746 10.1007/s10803-009-0840-2
13. Lane AE, Dennis SJ, Geraghty ME (2010) Brief report: Further evidence of sensory subtypes in autism. J Autism Dev Disord. doi: 10.1007/s10803-010-1103-y
14. Frith U (1992) Autism: explaining the Enigma. Blackwell, Oxford
15. M Hitoglou A Ververi A Antoniadis DI Zafeiriou 2010 Childhood autism and auditory system abnormalities Pediatr Neurol 42 309 314 20399382 10.1016/j.pediatrneurol.2009.10.009
16. S Khalfa N Bruneau B Roge N Georgieff E Veuillet JL Adrien C Barthelemy L Collet 2004 Increased perception of loudness in autism Hear Res 198 87 92 15617227 10.1016/j.heares.2004.07.006 (Pubitemid 39536158)
17. AM Tharpe FH Bess DP Sladen H Schissel S Couch T Schery 2006 Auditory characteristics of children with autism Ear Hear 27 430 441 16825892 10.1097/01.aud.0000224981.60575.d8 (Pubitemid 44357179)
18. CRG Jones F Happe G Baird E Simonoff AJS Marsden J Tregay R Phillips U Goswami JM Thomson T Charman 2009 Auditory discrimination and auditory sensory behaviours in autism spectrum disorders Neuropsychologia 47 2850 2858 19545576 10.1016/j.neuropsychologia.2009.06.015
19. L Bennetto ES Kuschner SL Hyman 2007 Olfaction and taste processing in autism Biol Psychiatry 62 1015 1021 17572391 10.1016/j.biopsych.2007.04.019 (Pubitemid 47562372)
20. Volkmar FR, Paul R, Klin A, Cohen D (eds) (2005) Handbook of Autism and pervasive developmental disorders, 3rd edn. John Wiley & Sons, New York
21. LD Wiggins DL Robins R Bakeman LB Adamson 2009 Brief report: sensory abnormalities as distinguishing symptoms of autism spectrum disorders in young children J Autism Dev Disord 39 1087 1091 19283461 10.1007/s10803-009-0711-x
22. Y Suzuki HD Critchley A Rowe P Howlin DGM McMurphy 2003 Impaired olfactory identification in Asperger's syndrome J Neuropsychiatry Clin Neurosci 15 105 107 12556580 10.1176/appi.neuropsych.15.1.105 (Pubitemid 36168088)
23. RL Doty P Shaman M Dann 1984 Development of the University of Pennsylvania Smell Identification Test: a standardized microencapsulated test of olfactory function Physiol Behav 32 489 502 6463130 10.1016/0031-9384(84)90269- 5 1:STN:280:DyaL2c3ntlSlsA%3D%3D (Pubitemid 14148126)
24. WJ Brewer A Brereton BJ Tonge 2008 Dissociation of age and ability on a visual analogue of the University of Pennsylvania Smell Identification Test in children with autism Res Autism Spectr Disord 2 612 620 10.1016/j.rasd.2008.01. 003
25. May T, Brewer WJ, Rinehart NJ, Enticott PG, Brereton AV, Tonge BJ (2010) Differential olfactory identification in children with autism and Asperger's disorder: a comparative and longitudinal study. J Autism Dev Disord. doi: 10.1007/s10803-010-1101-0
26. M Hrdlicka J Vodicka M Havlovicova T Urbanek M Blatny I Dudova 2011 Brief report: significant differences in perceived odor pleasantness found in children with ASD J Autism Dev Disord 41 524 527 20697793 10.1007/s10803-010- 1084-x
27. C Lord M Rutter A LeCouteur 1994 Autism diagnostic interview-revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders J Autism Dev Disord 24 659 685 7814313 10.1007/BF02172145 1:STN:280:DyaK2M7htlOlsg%3D%3D (Pubitemid 24309810)
28. E Schopler RJ Reichler RF DeVellis K Daly 1980 Toward objective classification of childhood autism: childhood autism rating scale (CARS) J Autism Dev Disord 10 91 103 6927682 10.1007/BF02408436 1:STN:280: DyaL2s%2Fls1yrsA%3D%3D (Pubitemid 10050041)
29. J Williams F Scott C Stott C Allison P Bolton S Baron-Cohen, et al. 2005 The CAST (Childhood Asperger Syndrome Test) Autism 9 45 68 15618262 10.1177/1362361305049029 (Pubitemid 40201929)
30. World Health Organization (1992) International classification of diseases, 10th edn. WHO, Geneva
31. T Hummel B Sekinger SR Wolf E Pauli G Kobal 1997 'Sniffin' Sticks': olfactory performance assessed by the combined testing of odor identification, odor discrimination and olfactory threshold Chem Senses 22 39 52 9056084 10.1093/chemse/22.1.39 1:STN:280:DyaK2s3gvFWnsA%3D%3D (Pubitemid 27142122)
32. G Kobal L Klimek M Wolfensberger H Gudziol A Temmel CM Owen, et al. 2000 Multicenter investigation of 1, 036 subjects using a standardized method for the assessment of olfactory function combining tests of odor identification, odor discrimination, and olfactory thresholds Eur Arch Otorhinolaryngol 257 205 211 10867835 10.1007/s004050050223 1:STN:280:DC%2BD3cvotVemsA%3D%3D (Pubitemid 30259061)
33. J Vodicka A Pellant V Chrobok 2007 Screening of olfactory function using odourized markers Rhinology 45 164 168 17708466 1:STN:280:DC%2BD2svovFymsQ%3D%3D
34. Moye LA (2003) Multiple analyses in clinical trials. Springer, New York
35. Doty RL (2003) Handbook of olfaction and gustation, 2nd edn. Marcel Dekker, New York
36. BS Naik N Shetty EVS Maben 2010 Drug-induced taste disorders Eur J Intern Med 21 240 243 20493431 10.1016/j.ejim.2010.01.017 1:CAS:528: DC%2BC3cXmsVemt7g%3D
37. GC Passali M Ralli J Galli L Calo G Paludetti 2008 How relevant is the impairment of smell for the quality of life in allergic rhinitis? Curr Opin Allergy Clin Immunol 8 238 242 18560299 10.1097/ACI.0b013e3282ffd6bb
38. JM Guilemany A Garcia-Pinero I Alobid S Cardelus S Centellas J Bartra A Valero C Picado J Mullol 2009 Persistent allergic rhinitis has a moderate impact on the sense of smell, depending on both nasal congestion and inflammation Laryngoscope 119 233 238 19160389 10.1002/lary.20075 1:CAS:528: DC%2BD1MXntFWks78%3D
39. WJ Fokkens VJ Lund J Mullol, et al. 2007 European position paper on nasal polyps Rhinology 45 1 139