Extracellular matrix remodeling and cell phenotypic changes in dysplastic and hemodynamically altered semilunar human cardiac valves

Cardiovascular Pathology

Volumn 20, Issue 5, 2011, Pages

  Stephens, Elizabeth H ^a   Shangkuan, Jennifer ^b   Kuo, Joyce J ^a   Carroll, Joshua L ^a   Kearney, Debra L ^c   Carberry, Kathleen E ^c   Fraser Jr , Charles D ^c   Grande Allen, K Jane ^a  

^a Rice University   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c TEXAS CHILDREN S HOSPITAL   (United States)

Author keywords

Congenital valve; Dysplastic; Extracellular matrix; Hemodynamics; Semilunar valve; Valvular interstitial cell

Indexed keywords

CARDIAC MYOSIN; COLLAGEN; HYALURONIC ACID; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE;

ADOLESCENT; ADULT; AORTA VALVE; ARTICLE; CELL ACTIVATION; CHILD; CLINICAL ARTICLE; COLLAGEN SYNTHESIS; CONSERVATIVE TREATMENT; CONTROLLED STUDY; DYSPLASIA; ELASTIC FIBER; EXTRACELLULAR MATRIX; FEMALE; FLOW CYTOMETRY; HEART HEMODYNAMICS; HEART MUSCLE CELL; HEART VALVE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFANT; MALE; MICROSCOPY; MITRAL VALVE; PHENOTYPE; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; TISSUE LEVEL; VALVULAR HEART DISEASE;

ADAPTATION, PHYSIOLOGICAL; ADOLESCENT; ADULT; AORTIC VALVE; CHILD; CHILD, PRESCHOOL; COLLAGEN; ELASTIC TISSUE; EXTRACELLULAR MATRIX; FEMALE; HEART DEFECTS, CONGENITAL; HEART VALVE DISEASES; HEMODYNAMICS; HUMANS; HYALURONIC ACID; INFANT; MALE; PHENOTYPE; PROCOLLAGEN-PROLINE DIOXYGENASE; PULMONARY VALVE; YOUNG ADULT;

EID: 80052433617     PISSN: 10548807     EISSN: 18791336     Source Type: Journal    
DOI: 10.1016/j.carpath.2010.07.004     Document Type: Article

References (23)

1. LeBlanc JG, and Russell JL Pediatric cardiac surgery in the 1990's Surg Clin North Am 78 1998 729 747
2. National Center for Health Statistics: National Heart, Lung, Blood Institute; 2005.
3. Hoffman J Congenital heart disease and inheritance Pediatr Clin North Am 37 1990 25 43
4. Ross DN Replacement of aortic and mitral valves with a pulmonary autograft Lancet 2 1967 956 958
5. Gupta V, Barzilla JE, Mendez JS, Stephens EH, Lee EL, and Collard CD Abundance and location of proteoglycans and hyaluronan within normal and myxomatous mitral valves Cardiovasc Pathol 18 2009 191 197
6. Stephens EH, and Grande-Allen KJ Age-related changes in collagen synthesis and turnover in porcine heart valves J Heart Valve Dis 16 2007 672 682 (Pubitemid 350238225)
7. Stephens EH, Carroll JL, and Grande-Allen KJ The use of collagenase III for the isolation of porcine aortic valvular interstitial cells: rationale and optimization J Heart Valve Dis 16 2007 175 183
8. Blevins TL, Carroll JL, Raza AM, and Grande-Allen KJ Phenotypic characterization of isolated valvular interstitial cell subpopulations J Heart Valve Dis 15 2006 815 822 (Pubitemid 44816765)
9. Baig M Acid mucopolysaccharides of congenitally defective, rheumatic, and normal human aortic valves Am J Pathol 96 1979 771 780
10. Koullias GJ, Korkolis DP, Ravichandran P, Psyrri A, Hatzaras I, and Elefteriades JA Tissue microarray detection of matrix metalloproteinases, in diseased tricuspid and bicuspid aortic valves with or without pathology of the ascending aorta Eur J Cardiothorac Surg 26 2004 1098 1103 (Pubitemid 39487454)
11. Hinton RB Jr, Lincoln J, Deutsch GH, Osinska H, Manning PB, and Benson DW Extracellular matrix remodeling and organization in developing and diseased aortic valves Circ Res 98 2006 1431 1438 (Pubitemid 43948068)
12. Bharati S, and Lev M Congenital polyvalvular disease Circulation 47 1973 575 586
13. Bartram U, Bartelings M, Kramer H, and Gittenberger-de Groot A Congenital polyvalvular disease: a review Pediatr Cardiol 22 2001 93 101 (Pubitemid 32147833)
14. Hyams V, and Manion W Incomplete differentiation of the cardiac valves Am Heart J 76 1968 173 182
15. Koretzky ED, Moller JH, Korns ME, Schwartz CJ, and Edwards JE Congenital pulmonary stenosis resulting from dysplasia of valve Circulation 40 1969 43 53
16. Balachandran K, Konduri S, Sucosky P, Jo H, and Yoganathan AP An ex vivo study of the biological properties of porcine aortic valves in response to circumferential cyclic stretch Ann Biomed Eng 34 2006 1655 1665 (Pubitemid 44704821)
17. Balachandran K, Sucosky P, Jo H, and Yoganathan AP Elevated cyclic stretch alters matrix remodeling in aortic valve cusps: implications for degenerative aortic valve disease Am J Physiol Heart Circ Physiol 296 2009 H756 H764
18. Rabkin-Aikawa E, Aikawa M, Farber M, Kratz JR, Garcia-Cardena G, and Kouchoukos NT Clinical pulmonary autograft valves: pathologic evidence of adaptive remodeling in the aortic site J Thorac Cardiovasc Surg 128 2004 552 561 (Pubitemid 39278389)
19. Aikawa E, Whittaker P, Farber M, Mendelson K, Padera RF, and Aikawa M Human semilunar cardiac valve remodeling by activated cells from fetus to adult: implications for postnatal adaptation, pathology, and tissue engineering Circulation 113 2006 1344 1352 (Pubitemid 43739456)
20. Stephens EH, de Jonge N, McNeill MP, Durst CA, and Grande-Allen KJ Age-related changes in material behavior of porcine mitral and aortic valves and correlation to matrix composition Tissue Eng Part A 16 2010 867 878
21. Merryman WD, Liao J, Parekh A, Candiello JE, Lin H, and Sacks MS Differences in tissue-remodeling potential of aortic and pulmonary heart valve interstitial cells Tissue Eng 13 2007 2281 2289 (Pubitemid 47404443)
22. Della Rocca F, Sartore S, Guidolin D, Bertiplaglia B, Gerosa G, and Casarotto D Cell composition of the human pulmonary valve: a comparative study with the aortic valve-the VESALIO Project. Vitalitate Exornatum Succedaneum Aorticum labore Ingegnoso Obtinebitur Ann Thorac Surg 70 2000 1594 1600
23. Aldous IG, Veres SP, Jahangir A, and Lee JM Differences in collagen cross-linking between the four valves of the bovine heart: a possible role in adaptation to mechanical fatigue Am J Physiol Heart Circ Physiol 296 2009 H1898 H1906