Identification of novel accessible proteins bearing diagnostic and therapeutic potential in human pancreatic ductal adenocarcinoma

Journal of Proteome Research

Volumn 10, Issue 9, 2011, Pages 4302-4313

  Turtoi, Andrei ^a,b   Musmeci, Davide ^a,c   Wang, Yinghong ^a   Dumont, Bruno ^a   Somja, Joan ^b   Bevilacqua, Generoso ^c   De Pauw, Edwin ^b   Delvenne, Philippe ^b   Castronovo, Vincent ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c UNIVERSITY HOSPITAL OF PISA   (Italy)

Author keywords

accessible proteins; biomarkers; pancreas cancer; proteomics

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; BIOTINYLATION; CANCER DIAGNOSIS; CONTROLLED STUDY; DIAGNOSTIC VALUE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL; PROTEIN ANALYSIS; QUANTITATIVE ANALYSIS; TANDEM MASS SPECTROMETRY; UNINDEXED SEQUENCE; WESTERN BLOTTING;

BIOTINYLATION; BLOTTING, WESTERN; CARCINOMA, PANCREATIC DUCTAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLUSTER ANALYSIS; HUMANS; IMMUNOHISTOCHEMISTRY; NEOPLASM PROTEINS; PANCREATIC NEOPLASMS; PROTEOMICS; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY; TUMOR MARKERS, BIOLOGICAL;

EID: 80052429405     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr200527z     Document Type: Article

References (30)

1. Jemal, A; Siegel, R; Ward, E; Hao, Y; Xu, J; Thun, M. J. Cancer statistics, 2009 CA Cancer J. Clin. 2009, 59 (4) 225-49
2. Duffy, M. J.; Sturgeon, C; Lamerz, R; Haglund, C; Holubec, V. L.; Klapdor, R; Nicolini, A; Topolcan, O; Heinemann, V. Tumor markers in pancreatic cancer: a European Group on Tumor Markers (EGTM) status report Ann. Oncol. 2010, 21 (3) 441-7
3. Philip, P. A.; Mooney, M; Jaffe, D; Eckhardt, G; Moore, M; Meropol, N; Emens, L; O'Reilly, E; Korc, M; Ellis, L; Benedetti, J; Rothenberg, M; Willett, C; Tempero, M; Lowy, A; Abbruzzese, J; Simeone, D; Hingorani, S; Berlin, J; Tepper, J. Consensus report of the national cancer institute clinical trials planning meeting on pancreas cancer treatment J. Clin. Oncol. 2009, 27 (33) 5660-9
4. Tonack, S; ASPNinall-O'Dea, M; Neoptolemos, J. P.; Costello, E. Pancreatic cancer: proteomic approaches to a challenging disease Pancreatology 2009, 9 (5) 567-76
5. Turtoi, A; De Pauw, E; Castronovo, V. Innovative proteomics for the discovery of systemically accessible cancer biomarkers suitable for imaging and targeted therapies Am. J. Pathol. 2011, 178 (1) 12-8
6. Castronovo, V.; Kischel, P.; Guillonneau, F.; de Leval, L.; Deféchereux, T.; De Pauw, E.; Neri, D.; Waltregny, D. Identification of specific reachable molecular targets in human breast cancer using a versatile ex vivo proteomic method Proteomics 2007, 7, 1188-1196 (Pubitemid 46716046)
7. Ishihama, Y; Oda, Y; Tabata, T; Sato, T; Nagasu, T; Rappsilber, J; Mann, M. Exponentially modified protein abundance index (emPAI) for estimation of absolute protein amount in proteomics by the number of sequenced peptides per protein Mol. Cell. Proteomics 2005, 4 (9) 1265-72 (Pubitemid 41448714)
8. Jensen, L. J.; Kuhn, M; Stark, M; Chaffron, S; Creevey, C; Muller, J; Doerks, T; Julien, P; Roth, A; Simonovic, M; Bork, P; von Mering, C. STRING 8 - a global view on proteins and their functional interactions in 630 organisms Nucleic Acids Res. 2009, Database) D412-6
9. Chen, R; Yi, E. C.; Donohoe, S; Pan, S; Eng, J; Cooke, K; Crispin, D. A.; Lane, Z; Goodlett, D. R.; Bronner, M. P.; Aebersold, R; Brentnall, T. A. Pancreatic cancer proteome: the proteins that underlie invasion, metastasis, and immunologic escape Gastroenterology 2005, 129, 1187-97 (Pubitemid 41446859)
10. Chung, J. C.; Oh, M. J.; Choi, S. H.; Bae, C. D. Proteomic analysis to identify biomarker proteins in pancreatic ductal adenocarcinoma ANZ J. Surg. 2008, 78, 245-51 (Pubitemid 351432692)
11. Qi, T; Han, J; Cui, Y; Zong, M; Liu, X; Zhu, B. Comparative proteomic analysis for the detection of biomarkers in pancreatic ductal adenocarcinomas J. Clin. Pathol. 2008, 61, 49-58 (Pubitemid 351158225)
12. Lu, Z; Hu, L; Evers, S; Chen, J; Shen, Y. Differential expression profiling of human pancreatic adenocarcinoma and healthy pancreatic tissue Proteomics 2004, 4, 3975-88 (Pubitemid 39657472)
13. Shen, J; Person, M. D.; Zhu, J; Abbruzzese, J. L.; Li, D. Protein expression profiles in pancreatic adenocarcinoma compared with normal pancreatic tissue and tissue affected by pancreatitis as detected by two-dimensional gel electrophoresis and mass spectrometry Cancer Res. 2004, 64, 9018-26 (Pubitemid 39665512)
14. Shekouh, A. R.; Thompson, C. C.; Prime, W; Campbell, F; HamLett, J; Herrington, C. S.; Lemoine, N. R.; Crnogorac-Jurcevic, T; Buechler, M. W.; Friess, H; Neoptolemos, J. P.; Pennington, S. R.; Costello, E. Application of laser capture microdissection combined with two-dimensional electrophoresis for the discovery of differentially regulated proteins in pancreatic ductal adenocarcinoma Proteomics 2003, 3, 1988-2001 (Pubitemid 37305893)
15. Mikuriya, K; Kuramitsu, Y; Ryozawa, S; Fujimoto, M; Mori, S; Oka, M; Hamano, K; Okita, K; Sakaida, I; Nakamura, K. Expression of glycolytic enzymes is increased in pancreatic cancerous tissues as evidenced by proteomic profiling by two-dimensional electrophoresis and liquid chromatography-mass spectrometry/mass spectrometry Int. J. Oncol. 2007, 30, 849-55
16. Bernatchez, P. N.; Acevedo, L; Fernandez-Hernando, C; Murata, T; Chalouni, C; Kim, J; Erdjument-Bromage, H; Shah, V; Gratton, J. P.; McNally, E. M.; Tempst, P; Sessa, W. C. Myoferlin regulates vascular endothelial growth factor receptor-2 stability and function J. Biol. Chem. 2007, 282 (42) 30745-53 (Pubitemid 350035229)
17. Yuan, Y; Nymoen, D. A.; Stavnes, H. T.; Rosnes, A. K.; Bjørang, O; Wu, C; Nesland, J. M.; Davidson, B. Tenascin-X is a novel diagnostic marker of malignant mesothelioma Am. J. Surg. Pathol. 2009, 33 (11) 1673-82
18. Mangasser-Stephan, K; Gartung, C; Lahme, B; Gressner, A. M. Expression of isoforms and splice variants of the latent transforming growth factor beta binding protein (LTBP) in cultured human liver myofibroblasts Liver 2001, 21, 105-113 (Pubitemid 32409537)
19. Gabrielsen, A; Lawler, P. R.; Yongzhong, W; Steinbruchel, D; Blagoja, D; Paulsson-Berne, G; Kastrup, J; Hansson, G. K. Gene expression signals involved in ischemic injury, extracellular matrix composition and fibrosis defined by global mRNA profiling of the human left ventricular myocardium J. Mol. Cell. Cardiol. 2007, 42, 870-83 (Pubitemid 46546392)
20. Vehvilainen, P; Hyytiainen, M; Keski-Oja, J. Latent transforming growth factor-beta-binding protein 2 is an adhesion protein for melanoma cells J. Biol. Chem. 2003, 278, 24705-13 (Pubitemid 37548627)
21. Ahmed, W; Kucich, U; Abrams, W; Bashir, M; Rosenbloom, J; Segade, F; Mecham, R. Signaling pathway by which TGF-beta1 increases expression of latent TGF-beta binding protein-2 at the transcriptional level Connect. Tissue Res. 1998, 37, 263-76 (Pubitemid 28547796)
22. Ivanov, S. V.; Ivanova, A. V.; Salnikow, K; Timofeeva, O; Subramaniam, M; Lerman, M. I. Two novel VHL targets, TGFBI (BIGH3) and its transactivator KLF10, are up-regulated in renal clear cell carcinoma and other tumors Biochem. Biophys. Res. Commun. 2008, 370, 536-40
23. Ma, C; Rong, Y; Radiloff, D. R.; Datto, M. B.; Centeno, B; Bao, S; Cheng, A. W.; Lin, F; Jiang, S; Yeatman, T. J.; Wang, X. F. Extracellular matrix protein betaig-h3/TGFBI promotes metastasis of colon cancer by enhancing cell extravasation Genes Dev. 2008, 22, 308-21 (Pubitemid 351214273)
24. Golembieski, W. A.; Rempel, S. A. cDNA array analysis of SPARC-modulated changes in glioma gene expression J. Neurooncol. 2002, 60, 213-26 (Pubitemid 35439176)
25. Yamanaka, M; Kimura, F; Kagata, Y; Kondoh, N; Asano, T; Yamamoto, M; Hayakawa, M. BIGH3 is overexpressed in clear cell renal cell carcinoma Oncol. Rep. 2008, 19, 865-874 (Pubitemid 351802653)
26. Lorenzo, P; Aspberg, A; Onnerfjord, P; Bayliss, M. T.; Neame, P. J.; Heinegard, D. Identification and characterization of asporin. a novel member of the leucine-rich repeat protein family closely related to decorin and biglycan J. Biol. Chem. 2001, 276, 12201-11
27. Park, E. S.; Cho, H. S.; Kwon, T. G.; Jang, S. N.; Lee, S. H.; An, C. H.; Shin, H. I.; Kim, J. Y.; Cho, J. Y. Proteomics Analysis of Human Dentin Reveals Distinct Protein Expression Profiles J. Proteome Res. 2009, 8 (3) 1338-46
28. Nakajima, M; Kizawa, H; Saitoh, M; Kou, I; Miyazono, K; Ikegawa, S. Mechanisms for asporin function and regulation in articular cartilage J. Biol. Chem. 2007, 282 (44) 32185-92 (Pubitemid 350106455)
29. Turashvili, G; Bouchal, J; Baumforth, K; Wei, W; Dziechciarkova, M; Ehrmann, J; Klein, J; Fridman, E; Skarda, J; Srovnal, J; Hajduch, M; Murray, P; Kolar, Z. Novel markers for differentiation of lobular and ductal invasive breast carcinomas by laser microdissection and microarray analysis BMC Cancer 2007, 7, 55
30. Martin, M. D.; Matrisian, L. M. The other side of MMPs: protective roles in tumor progression Cancer Metastasis Rev. 2007, 26 (3-4) 717-24 (Pubitemid 350115119)