Antiphospholipid antibodies and antiphospholipid syndrome: Role in portal vein thrombosis in patients with and without liver cirrhosis

Clinical and Applied Thrombosis/Hemostasis

Volumn 17, Issue 4, 2011, Pages 367-370

  Amitrano, Lucio ^a   Ames, Paul R J ^b   Guardascione, Maria Anna ^a   Lopez, Luis R ^c   Menchise, Antonella ^a   Brancaccio, Vincenzo ^a   Iannaccone, Luigi ^a   Balzano, Antonio ^a  

^a CARDARELLI HOSPITAL   (Italy)

^b ROYAL PRESTON HOSPITAL   (United Kingdom)

^c Operations and Technology   (United States)

Author keywords

antiphosholipid; cirrhosis; portal; thrombosis

Indexed keywords

BETA2 GLYCOPROTEIN 1 ANTIBODY; CARDIOLIPIN ANTIBODY; IMMUNOGLOBULIN G; LUPUS ANTICOAGULANT; OXIDIZED LOW DENSITY LIPOPROTEIN ANTIBODY; PHOSPHOLIPID ANTIBODY;

ADULT; AGED; ANTIBODY TITER; ANTIPHOSPHOLIPID SYNDROME; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; FEMALE; HUMAN; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; PORTAL VEIN THROMBOSIS; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES, ANTIPHOSPHOLIPID; ANTIPHOSPHOLIPID SYNDROME; FEMALE; HUMANS; LIVER CIRRHOSIS; MALE; MIDDLE AGED; PORTAL VEIN; THROMBOSIS; YOUNG ADULT;

EID: 80052425756     PISSN: 10760296     EISSN: 19382723     Source Type: Journal    
DOI: 10.1177/1076029610369797     Document Type: Article

References (28)

1. Miyakis S., Lockshin MD, Atsumi T., et al. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost. 2006 ; 4 (2). 295-306.
2. Matsuura E., Igarashi Y., Fujimoto M., Ichikawa K., Koike T. Anticardiolipin cofactor(s) and differential diagnosis of autoimmune disease. Lancet. 1990 ; 336 (8708). 177-178. (Pubitemid 20225005)
3. Day HM, Thiagarajan P., Ahn C., Reveille JD, Tinker KF, Arnett FC Autoantibodies to beta2-glycoprotein I in systemic lupus erythematosus and primary antiphospholipid antibody syndrome: clinical correlations in comparison with other antiphospholipid antibody tests. J Rheumatol. 1998 ; 25 (4). 667-674. (Pubitemid 28212373)
4. Reber G., de Moerloose P. Anti-beta2 glycoprotein I antibodies-when and how should they be measured ? Thromb Res. 2004 ; 114 (5-6). 527-531. (Pubitemid 39422587)
5. Greaves M. Antiphospholipid antibodies and thrombosis. Lancet. 1999 ; 353 (9161). 1348-1353. (Pubitemid 29178795)
6. Kobayashi K., Kishi M., Atsumi T., et al. Circulating oxidized LDL forms complexes with 2-glycoprotein I: implication as an atherogenic autoantigen. J Lipid Res. 2003 ; 44 (4). 716-726. (Pubitemid 37279673)
7. Lopez D., Garcia-Valladares I., Palafox-Sanchez C., et al. Oxidized low density lipoprotein/beta2glycoprotein I complex and autoantibodies to oxLig-1/beta2glycoprotein I in patients with systemic lupus erythematosus and antiphospholipid syndrome. Am J Clin Pathol. 2004 ; 121 (3). 426-436. (Pubitemid 38298177)
8. Kasahara J., Kobayashi K., Maeshima Y., et al. Clinical significance of serum oxidized low-density lipoprotein/beta2-glycoprotein I complexes in patients with chronic renal diseases. Nephron Clin Pract. 2004 ; 98 (1). 15-24.
9. Lopez LR, Hurley BL, Simpson DF, Matsuura E. Oxidized low-density lipoprotein/beta2-glycoprotein I complexes and autoantibodies in patients with type 2 diabetes mellitus. Ann N Y Acad Sci. 2005 ; 1051: 97-103. (Pubitemid 41362736)
10. Levine JS, Branch DW, Rauch J. The antiphospholipid syndrome. N Engl J Med. 2002 ; 346 (10). 752-763. (Pubitemid 34983997)
11. Neville C., Rauch J., Kassis J., et al. Thromboembolic risk in patients with high titre anticardiolipin and multiple antiphospholipid antibodies. Thromb Haemost. 2003 ; 90 (1). 108-115. (Pubitemid 36873866)
12. Romero-Gomez M., Suarez Garcia E., Lopez Lacomba D., Marchante I., Grande L., Castro Fernandez M. Antiphospholipid antibodies are related to portal vein thrombosis in patients with liver cirrhosis. J Clin Gastroenterol. 2000 ; 31 (3). 237-240.
13. Oksuzoglu G., Bayraktar Y., Arslan S., et al. Portal vein thrombosis in cirrhotics: related with anticardiolipin antibodies ? Hepatogastroenterology. 2003 ; 50 (53). 1527-1530. (Pubitemid 37186524)
14. Elefsiniotis IS, Diamantis ID, Dourakis SP, Kafiri G., Pantazis K., Mavrogiannis C. Anticardiolipin antibodies in chronic hepatitis B and chronic hepatitis D infection, and hepatitis B-related hepatocellular carcinoma. Relationship with portal vein thrombosis. Eur J Gastroenterol Hepatol. 2003 ; 15 (7). 717-719.
15. Racine A., Nahon S., Jouannaud V., Caugant H., Lesgourgues B. Portal vein thrombosis in a patient with quiescent Crohn's disease associated with hyperhomocysteinemia and antiphospholipid antibody syndrome 1-yr after an ileocecal resection. Am J Gastroenterol. 2008 ; 103 (2). 499-501. (Pubitemid 351248743)
16. Egesel T., Unsal I., Bayraktar Y. Antiphospholipid antibodies and lipoprotein (a) as etiologic or contributory factors in patients with idiopathic cavernous transformation of portal vein. Turk J Gastroenterol. 2002 ; 13 (2). 89-93. (Pubitemid 34764755)
17. Amitrano L., Guardascione MA, Brancaccio V., et al. Risk factors and clinical presentations of portal vein thrombosis in patients with liver cirrhosis. J Hepatol. 2004 ; 40 (5). 736-741. (Pubitemid 38507352)
18. Amitrano L., Guardascione MA, Scaglione M., et al. Prognostic factors in noncirrhotic patients with splanchnic vein thromboses. Am J Gastroenterol. 2007 ; 102 (11). 2464-2470. (Pubitemid 47631782)
19. Greaves M., Cohen H., MacHin SJ, Mackie I. Guidelines on the investigation and management of the antiphospholipid syndrome. Br J Haematol. 2000 ; 109 (4). 704-715. (Pubitemid 30609746)
20. Mateo J., Pliver A., Borrell M., Sala N., Fontcuberta J. Laboratory evaluation and clinical characteristic of 2132 consecutive unselected patients with venous thromboembolism-results of the Spanish Multicentric Study on Thrombophilia (EMET-Study). Thromb Haemost. 1997 ; 77 (3). 444-451. (Pubitemid 27121006)
21. Denninger MH, Chait Y., Casadevall N., et al. Cause of portal vein thrombosis in adults: the role of multiple concurrent factors. Hepatology. 2000 ; 31 (3). 587-591. (Pubitemid 30118625)
22. Ordi-Ros J., Villarreal J., Monegal F., Sauleda S., Esteban I., Vilardell M. Anticardiolipin antibodies in patients with chronic hepatitis C virus infection: characterization in relation to antiphosholipid syndrome. Clin Diagn Lab Immunol. 2000 ; 7 (2). 241-244. (Pubitemid 30132118)
23. Harada M., Fujisawa Y., Sakisaka S., et al. High prevalence of anticardiolipin antibodies in hepatitis C virus infection: lack of effects on thrombocytopenia and thrombotic complications. J Gastroenterol. 2000 ; 35 (4). 272-277. (Pubitemid 30229740)
24. Mangia A., Margaglione M., Cascavilla I., et al. Anticardiolipin antibodies in patients with liver disease. Am J Gastroenterol. 1999 ; 94 (10). 2983-2987. (Pubitemid 29482769)
25. Violi F., Ferro D., Basili S., et al. Relation between lupus anticoagulant and splanchnic venous thrombosis in cirrhosis of the liver. BMJ. 1994 ; 309 (6949). 239-240. (Pubitemid 24252660)
26. Primignani M., Martinelli I., Bucciarelli P., et al. Risk factors for thrombophilia in extrahepatic portal vein obstruction. Hepatology. 2005 ; 41 (3). 603-608. (Pubitemid 40289509)
27. Janseen HLA, Meinardi JR, Vleggaar FP, van Huum SHM, Haagsma EB, van der Meer FJM. Factor V. Leiden mutation, pro-thrombin gene mutation, and deficiencies in coagulation inhibitors associated with Budd-Chiari syndrome and portal vein thrombosis: results of a case-control study. Blood. 2000 ; 96 (7). 2364-2368.
28. Rolla R., Vay D., Mottaran E., et al. Antiphospholipid antibodies associated with alcoholic liver disease specifically recognize oxidised phospholipids. Gut. 2001 ; 49 (6). 852-859. (Pubitemid 33096045)