Transforming growth factor-β-activated kinase 1 regulates natural killer cell-mediated cytotoxicity and cytokine production

Journal of Biological Chemistry

Volumn 286, Issue 36, 2011, Pages 31213-31224

  Rajasekaran, Kamalakannan ^a   Chu, Haiyan ^a   Kumar, Pawan ^a   Xiao, Yechen ^c   Tinguely, Mathew ^a   Samarakoon, Asanga ^a   Kim, Tae Whan ^b   Li, Xiaoxia ^b   Thakar, Monica S ^a   Zhang, Jiwang ^c   Malarkannan, Subramaniam ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASES; CYTOKINE PRODUCTION; CYTOKINES; GUANYLATE KINASE; IN-VIVO; NATURAL KILLER; NK CELLS; PHARMACOLOGICAL INHIBITORS; SIGNALING CASCADES; SIGNALING MOLECULES; TRANSFORMING GROWTH FACTORS;

CELL DEATH; CHEMICAL ACTIVATION; ENZYMES; MAMMALS; PEPTIDES; PHOSPHORYLATION; SIGNALING;

CYTOTOXICITY;

CARMA1; CHEMOKINE; CYTOKINE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE P38; NATURAL KILLER CELL RECEPTOR NKG2D; RANTES; STRESS ACTIVATED PROTEIN KINASE 1; TRANSCRIPTION FACTOR AP 1; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; IN VIVO STUDY; LYMPHOCYTE ACTIVATION; MOUSE; NATURAL KILLER CELL; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN DEPLETION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS REGULATION;

ANIMALS; CARD SIGNALING ADAPTOR PROTEINS; CYTOKINES; CYTOTOXICITY, IMMUNOLOGIC; KILLER CELLS, NATURAL; MAP KINASE KINASE KINASES; MICE; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

MUS;

EID: 80052400379     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.261917     Document Type: Article

References (60)

1. Rawlings, D. J., Sommer, K., and Moreno-García, M. E. (2006) Nat. Rev. Immunol. 6, 799-812
2. Gaide, O., Martinon, F., Micheau, O., Bonnet, D., Thome, M., and Tschopp, J. (2001) FEBS Lett. 496, 121-127
3. Wang, D., You, Y., Case, S. M., McAllister-Lucas, L. M., Wang, L., DiStefano, P. S., Nuñez, G., Bertin, J., and Lin, X. (2002) Nat. Immunol. 3, 830-835
4. Gaide, O., Favier, B., Legler, D. F., Bonnet, D., Brissoni, B., Valitutti, S., Bron, C., Tschopp, J., and Thome, M. (2002) Nat. Immunol. 3, 836-843
5. Egawa, T., Albrecht, B., Favier, B., Sunshine, M. J., Mirchandani, K., O'Brien, W., Thome, M., and Littman, D. R. (2003) Curr. Biol. 13, 1252-1258
6. Newton, K., and Dixit, V. M. (2003) Curr. Biol. 13, 1247-1251
7. Jun, J. E., Wilson, L. E., Vinuesa, C. G., Lesage, S., Blery, M., Miosge, L. A., Cook, M. C., Kucharska, E. M., Hara, H., Penninger, J. M., Domashenz, H., Hong, N. A., Glynne, R. J., Nelms, K. A., and Goodnow, C. C. (2003) Immunity 18, 751-762
8. Hara, H., Ishihara, C., Takeuchi, A., Xue, L., Morris, S. W., Penninger, J. M., Yoshida, H., and Saito, T. (2008) J. Immunol. 181, 918-930
9. Gross, O., Grupp, C., Steinberg, C., Zimmermann, S., Strasser, D., Hannesschla ̈ger, N., Reindl, W., Jonsson, H., Huo, H., Littman, D. R., Peschel, C., Yokoyama, W. M., Krug, A., and Ruland, J. (2008) Blood 112, 2421-2428
10. Sun, L., Deng, L., Ea, C. K., Xia, Z. P., and Chen, Z. J. (2004) Mol. Cell 14, 289-301
11. Tang, M., Wei, X., Guo, Y., Breslin, P., Zhang, S., Zhang, S., Wei, W., Xia, Z., Diaz, M., Akira, S., and Zhang, J. (2008) J. Exp. Med. 205, 1611-1619
12. Sato, S., Sanjo, H., Takeda, K., Ninomiya-Tsuji, J., Yamamoto, M., Kawai, T., Matsumoto, K., Takeuchi, O., and Akira, S. (2005) Nat. Immunol. 6, 1087-1095
13. Regunathan, J., Chen, Y., Wang, D., and Malarkannan, S. (2005) Blood 105, 233-240
14. Malarkannan, S., Shih, P. P., Eden, P. A., Horng, T., Zuberi, A. R., Christianson, G., Roopenian, D., and Shastri, N. (1998) J. Immunol. 161, 3501-3509
15. Bennett, M., Yu, Y. Y., Stoneman, E., Rembecki, R. M., Mathew, P. A., Lindahl, K. F., and Kumar, V. (1995) Semin. Immunol. 7, 121-127
16. Mason, L. H., Anderson, S. K., Yokoyama, W. M., Smith, H. R., Winkler-Pickett, R., and Ortaldo, J. R. (1996) J. Exp. Med. 184, 2119-2128
17. Malarkannan, S., Horng, T., Eden, P., Gonzalez, F., Shih, P., Brouwenstijn, N., Klinge, H., Christianson, G., Roopenian, D., and Shastri, N. (2000) Immunity 13, 333-344
18. Fernandez-Sesma, A., Marukian, S., Ebersole, B. J., Kaminski, D., Park, M. S., Yuen, T., Sealfon, S. C., García-Sastre, A., and Moran, T. M. (2006) J. Virol. 80, 6295-6304
19. Guo, H., Samarakoon, A., Vanhaesebroeck, B., and Malarkannan, S. (2008) J. Exp. Med. 205, 2419-2435
20. Xue, L., Morris, S. W., Orihuela, C., Tuomanen, E., Cui, X., Wen, R., and Wang, D. (2003) Nat. Immunol. 4, 857-865
21. Ruland, J., Duncan, G. S., Elia, A., del Barco Barrantes, I., Nguyen, L., Plyte, S., Millar, D. G., Bouchard, D., Wakeham, A., Ohashi, P. S., and Mak, T. W. (2001) Cell 104, 33-42
22. Bauer, S., Groh, V., Wu, J., Steinle, A., Phillips, J. H., Lanier, L. L., and Spies, T. (1999) Science 285, 727-729
23. Cerwenka, A., Bakker, A. B., McClanahan, T., Wagner, J., Wu, J., Phillips, J. H., and Lanier, L. L. (2000) Immunity 12, 721-727
24. Diefenbach, A., Jensen, E. R., Jamieson, A. M., and Raulet, D. H. (2001) Nature 413, 165-171
25. Samarakoon, A., Chu, H., and Malarkannan, S. (2009) Mol. Immunol. 46, 1011-1019
26. Ljunggren, H. G., and Kärre, K. (1985) J. Exp. Med. 162, 1745-1759
27. Djeu, J. Y., Heinbaugh, J. A., Holden, H. T., and Herberman, R. B. (1979) J. Immunol. 122, 182-188
28. Dorner, B. G., Smith, H. R., French, A. R., Kim, S., Poursine-Laurent, J., Beckman, D. L., Pingel, J. T., Kroczek, R. A., and Yokoyama, W. M. (2004) J. Immunol. 172, 3119-3131
29. Jiang, K., Zhong, B., Gilvary, D. L., Corliss, B. C., Hong-Geller, E., Wei, S., and Djeu, J. Y. (2000) Nat. Immunol. 1, 419-425
30. Wei, S., Gilvary, D. L., Corliss, B. C., Sebti, S., Sun, J., Straus, D. B., Leibson, P. J., Trapani, J. A., Hamilton, A. D., Weber, M. J., and Djeu, J. Y. (2000) J. Immunol. 165, 3811-3819
31. Li, C., Ge, B., Nicotra, M., Stern, J. N., Kopcow, H. D., Chen, X., and Strominger, J. L. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 3017-3022
32. Trotta, R., Fettucciari, K., Azzoni, L., Abebe, B., Puorro, K. A., Eisenlohr, L. C., and Perussia, B. (2000) J. Immunol. 165, 1782-1789
33. Ninomiya-Tsuji, J., Kishimoto, K., Hiyama, A., Inoue, J., Cao, Z., and Matsumoto, K. (1999) Nature 398, 252-256
34. Greenblatt, M. B., Shim, J. H., Zou, W., Sitara, D., Schweitzer, M., Hu, D., Lotinun, S., Sano, Y., Baron, R., Park, J. M., Arthur, S., Xie, M., Schneider, M. D., Zhai, B., Gygi, S., Davis, R., and Glimcher, L. H. (2010) J. Clin. Invest. 120, 2457-2473
35. Geuking, P., Narasimamurthy, R., Lemaitre, B., Basler, K., and Leulier, F. (2009) PLoS One 4, e7709
36. Ventura, J. J., Kennedy, N. J., Lamb, J. A., Flavell, R. A., and Davis, R. J. (2003) Mol. Cell Biol. 23, 2871-2882
37. Sommer, K., Guo, B., Pomerantz, J. L., Bandaranayake, A. D., Moreno-García, M. E., Ovechkina, Y. L., and Rawlings, D. J. (2005) Immunity 23, 561-574
38. Matsumoto, R., Wang, D., Blonska, M., Li, H., Kobayashi, M., Pappu, B., Chen, Y., Wang, D., and Lin, X. (2005) Immunity 23, 575-585
39. Shinohara, H., Yasuda, T., Aiba, Y., Sanjo, H., Hamadate, M., Watarai, H., Sakurai, H., and Kurosaki, T. (2005) J. Exp. Med. 202, 1423-1431
40. Baud, V., Liu, Z. G., Bennett, B., Suzuki, N., Xia, Y., and Karin, M. (1999) Genes Dev. 13, 1297-1308
41. Schulze-Luehrmann, J., and Ghosh, S. (2006) Immunity 25, 701-715
42. Ninomiya-Tsuji, J., Kajino, T., Ono, K., Ohtomo, T., Matsumoto, M., Shiina, M., Mihara, M., Tsuchiya, M., and Matsumoto, K. (2003) J. Biol.Chem. 278, 18485-18490
43. Huang, H., Ryu, J., Ha, J., Chang, E. J., Kim, H. J., Kim, H. M., Kitamura, T., Lee, Z. H., and Kim, H. H. (2006) Cell Death Differ. 13, 1879-1891
44. Aramburu, J., Azzoni, L., Rao, A., and Perussia, B. (1995) J. Exp. Med. 182, 801-810
45. Upshaw, J. L., and Leibson, P. J. (2006) Semin. Immunol. 18, 167-175
46. Zompi, S., Hamerman, J. A., Ogasawara, K., Schweighoffer, E., Tybulewicz, V. L., Di Santo, J. P., Lanier, L. L., and Colucci, F. (2003) Nat. Immunol. 4, 565-572
47. Malarkannan, S., Regunathan, J., Chu, H., Kutlesa, S., Chen, Y., Zeng, H., Wen, R., and Wang, D. (2007) J. Immunol. 179, 3752-3762
48. Che, T., You, Y., Wang, D., Tanner, M. J., Dixit, V. M., and Lin, X. (2004) J. Biol. Chem. 279, 15870-15876
49. Fehniger, T. A., Shah, M. H., Turner, M. J., VanDeusen, J. B., Whitman, S. P., Cooper, M. A., Suzuki, K., Wechser, M., Goodsaid, F., and Caligiuri, M. A. (1999) J. Immunol. 162, 4511-4520
50. Watford, W. T., Hissong, B. D., Bream, J. H., Kanno, Y., Muul, L., and O'Shea, J. J. (2004) Immunol. Rev. 202, 139-156
51. Chen, X., Trivedi, P. P., Ge, B., Krzewski, K., and Strominger, J. L. (2007) Proc. Natl. Acad. Sci. U.S.A. 104, 6329-6334
52. Billadeau, D. D., Upshaw, J. L., Schoon, R. A., Dick, C. J., and Leibson, P. J. (2003) Nat. Immunol. 4, 557-564
53. Wu, J., Song, Y., Bakker, A. B., Bauer, S., Spies, T., Lanier, L. L., and Phillips, J. H. (1999) Science 285, 730-732
54. Wu, J., Cherwinski, H., Spies, T., Phillips, J. H., and Lanier, L. L. (2000) J. Exp. Med. 192, 1059-1068
55. Gilfillan, S., Ho, E. L., Cella, M., Yokoyama, W. M., and Colonna, M. (2002) Nat. Immunol. 3, 1150-1155
56. McVicar, D. W., Taylor, L. S., Gosselin, P., Willette-Brown, J., Mikhael, A. I., Geahlen, R. L., Nakamura, M. C., Linnemeyer, P., Seaman, W. E., Anderson, S. K., Ortaldo, J. R., and Mason, L. H. (1998) J. Biol. Chem. 273, 32934-32942
57. Arase, N., Arase, H., Park, S. Y., Ohno, H., Ra, C., and Saito, T. (1997) J. Exp. Med. 186, 1957-1963
58. Pende, D., Parolini, S., Pessino, A., Sivori, S., Augugliaro, R., Morelli, L., Marcenaro, E., Accame, L., Malaspina, A., Biassoni, R., Bottino, C., Moretta, L., and Moretta, A. (1999) J. Exp. Med. 190, 1505-1516
59. Sayós, J., Nguyen, K. B., Wu, C., Stepp, S. E., Howie, D., Schatzle, J. D., Kumar, V., Biron, C. A., and Terhorst, C. (2000) Int. Immunol. 12, 1749-1757
60. Welteke, V., Eitelhuber, A., Düwel, M., Schweitzer, K., Naumann, M., and Krappmann, D. (2009) EMBO Rep. 10, 642-648