An ENU-induced mutation in the Mertk gene (Mertk nmf12) leads to a slow form of retinal degeneration

Investigative Ophthalmology and Visual Science

Volumn 52, Issue 7, 2011, Pages 4703-4709

  Maddox, Dennis M ^a   Hicks, Wanda L ^a   Vollrath, Douglas ^b   LaVail, Matthew M ^c   Naggert, Jürgen K ^a   Nishina, Patsy M ^a  

^a JACKSON LABORATORY   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ETHYLNITROSOUREA; PROTEIN TYROSINE KINASE; TUMOR NECROSIS FACTOR; DNA; MERTK PROTEIN, MOUSE; ONCOPROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL MODEL; ANIMAL TISSUE; ANIMLA EXPERIMENT; APOPTOSIS; ARTICLE; C MER TYROSINE KINASE GENE; CHROMOSOME 2; CONTROLLED STUDY; DNA SEQUENCE; ELECTRORETINOGRAPHY; FLUORESCENCE MICROSCOPY; GENE; GENE MAPPING; GENE MUTATION; IMMUNOHISTOCHEMISTRY; INDUCED MUTATION; MICROSCOPY; MOUSE; NECROSIS; NEUROSCIENCE MUTAGENESIS FACILITY 12 MUTATION; NONHUMAN; PHENOTYPE; PHOTORECEPTOR; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA DEGENERATION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL DEATH; COMPARATIVE STUDY; DISEASE COURSE; DISEASE MODEL; DRUG EFFECT; GENETICS; METABOLISM; MUTATION; OPHTHALMOSCOPY; PATHOLOGY; PATHOPHYSIOLOGY; PHOTORECEPTOR CELL; RETINA;

ANIMALS; BLOTTING, WESTERN; CELL DEATH; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DNA; ELECTRORETINOGRAPHY; ETHYLNITROSOUREA; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; MUTATION; OPHTHALMOSCOPY; PHENOTYPE; PHOTORECEPTOR CELLS, VERTEBRATE; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RETINA; RETINAL DEGENERATION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80052375898     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.10-7077     Document Type: Article

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