RNA polymerase III under control: Repression and de-repression

Trends in Biochemical Sciences

Volumn 36, Issue 9, 2011, Pages 451-456

  Boguta, Magdalena ^a,b   Graczyk, Damian ^a  

^a INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

^b WARSAW UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

CASEIN KINASE II; DNA; DNA DIRECTED RNA POLYMERASE III; GLUCOSE; MAF1 KINASE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PROTEIN MAF1; REGULATOR PROTEIN; RNA 5S; TATA BINDING PROTEIN; TRANSFER DEOXYRIBONUCLEIC ACID; TRANSFER RNA; UNCLASSIFIED DRUG;

CARBON SOURCE; CHROMATIN; DNA PROTEIN COMPLEX; HUMAN; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; NUCLEOCYTOPLASMIC TRANSPORT; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; REVIEW; RNA GENE; RNA SYNTHESIS; RNA TRANSCRIPTION; TRANSCRIPTION REGULATION; TRANSCRIPTION REPRESSION;

CASEIN KINASE II; CHROMATIN; ENZYME REPRESSION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, FUNGAL; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; RNA POLYMERASE III; RNA, TRANSFER; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 80052366947     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tibs.2011.06.008     Document Type: Review

References (49)

1. Warner J.R. The economics of ribosome biosynthesis in yeast. Trends Biochem. Sci. 1999, 24:437-440.
2. Cabart P., et al. Facilitated recycling protects human RNA polymerase III from repression by Maf1 in vitro. J. Biol. Chem. 2008, 283:36108-36117.
3. Dieci G., Sentenac A. Facilitated recycling pathway for RNA polymerase III. Cell 1996, 84:245-252.
4. Dieci G., Sentenac A. Detours and shortcuts to transcription reinitiation. Trends Biochem. Sci. 2003, 28:202-209.
5. Pluta K., et al. Maf1p, a negative effector of RNA polymerase III in Saccharomyces cerevisiae. Mol. Cell. Biol. 2001, 21:5031-5040.
6. Oficjalska-Pham D., et al. General repression of RNA polymerase III transcription is triggered by protein phosphatase type 2A-mediated dephosphorylation of Maf1. Mol. Cell 2006, 22:623-632.
7. Reina J.H., et al. Maf1, a new player in the regulation of human RNA polymerase III transcription. PLoS ONE 2006, 1:e134.
8. Roberts D.N., et al. Dephosphorylation and genome-wide association of Maf1 with Pol III-transcribed genes during repression. Mol. Cell 2006, 22:633-644.
9. Kantidakis T., et al. mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:11823-11828.
10. Upadhya R., et al. Maf1 is an essential mediator of diverse signals that repress RNA polymerase III transcription. Mol. Cell 2002, 10:1489-1494.
11. Desai N., et al. Two steps in Maf1-dependent repression of transcription by RNA polymerase III. J. Biol. Chem. 2005, 280:6455-6462.
12. Willis I.M., Moir R.D. Integration of nutritional and stress signaling pathways by Maf1. Trends Biochem. Sci. 2007, 32:51-53.
13. Ciesla M., et al. Maf1 is involved in coupling carbon metabolism to RNA polymerase III transcription. Mol. Cell. Biol. 2007, 27:7693-7702.
14. Nguyen V.C., et al. Replication stress checkpoint signaling controls tRNA gene transcription. Nat. Struct. Mol. Biol. 2010, 17:976-981.
15. Moir R.D., et al. Protein kinase A regulates RNA polymerase III transcription through the nuclear localization of Maf1. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:15044-15049.
16. Huber A., et al. Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis. Genes Dev. 2009, 23:1929-1943.
17. Lee J., et al. Regulation of RNA polymerase III transcription involves SCH9-dependent and SCH9-independent branches of the target of rapamycin (TOR) pathway. J. Biol. Chem. 2009, 284:12604-12608.
18. Boguta M. Control of RNA polymerases I and III by the TOR signaling pathway. Cell Cycle 2009, 8:4023-4024.
19. Towpik J., et al. Derepression of RNA polymerase III transcription by phosphorylation and nuclear export of its negative regulator, Maf1. J. Biol. Chem. 2008, 283:17168-17174.
20. Wei Y., et al. Mechanisms of regulation of RNA polymerase III-dependent transcription by TORC1. EMBO J. 2009, 28:2220-2230.
21. Vannini A., et al. Molecular basis of RNA polymerase III transcription repression by Maf1. Cell 2010, 143:59-70.
22. Fernandez-Tornero C., et al. Conformational flexibility of RNA polymerase III during transcriptional elongation. EMBO J. 2010, 29:3762-3772.
23. Graczyk D., et al. Casein kinase II-mediated phosphorylation of general repressor Maf1 triggers RNA polymerase III activation. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:4926-4931.
24. Michels A.A., et al. mTORC1 directly phosphorylates and regulates human MAF1. Mol. Cell. Biol. 2010, 30:3749-3757.
25. Shor B., et al. Requirement of the mTOR kinase for the regulation of Maf1 phosphorylation and control of RNA polymerase III-dependent transcription in cancer cells. J. Biol. Chem. 2010, 285:15380-15392.
26. Boguta M., et al. Mutation in a new gene MAF1 affects tRNA suppressor efficiency in Saccharomyces cerevisiae. Gene 1997, 185:291-296.
27. Landrieux E., et al. A subcomplex of RNA polymerase III subunits involved in transcription termination and reinitiation. EMBO J. 2006, 25:118-128.
28. de Nadal E., Posas F. Multilayered control of gene expression by stress-activated protein kinases. EMBO J. 2010, 29:4-13.
29. Fiedler D., et al. Functional organization of the S. cerevisiae phosphorylation network. Cell 2009, 136:952-963.
30. Michels A.A. MAF1: a new target of mTORC1. Biochem. Soc. Trans. 2011, 39:487-491.
31. Ghavidel A., Schultz M.C. Casein kinase II regulation of yeast TFIIIB is mediated by the TATA-binding protein. Genes Dev. 1997, 11:2780-2789.
32. Ghavidel A., Schultz M.C. TATA binding protein-associated CK2 transduces DNA damage signals to the RNA polymerase III transcriptional machinery. Cell 2001, 106:575-584.
33. Hu P., et al. CK2 phosphorylation of Bdp1 executes cell cycle-specific RNA polymerase III transcription repression. Mol. Cell 2004, 16:81-92.
34. Hu P., et al. A minimal RNA polymerase III transcription system from human cells reveals positive and negative regulatory roles for CK2. Mol. Cell 2003, 12:699-709.
35. Johnston I.M., et al. CK2 forms a stable complex with TFIIIB and activates RNA polymerase III transcription in human cells. Mol. Cell. Biol. 2002, 22:3757-3768.
36. Schultz M.C. DNA damage regulation of the RNA components of the translational apparatus: new biology and mechanisms. IUBMB Life 2003, 55:243-247.
37. Buratowski S. Progression through the RNA polymerase II CTD cycle. Mol. Cell 2009, 36:541-546.
38. Moqtaderi Z., Struhl K. Genome-wide occupancy profile of the RNA polymerase III machinery in Saccharomyces cerevisiae reveals loci with incomplete transcription complexes. Mol. Cell. Biol. 2004, 24:4118-4127.
39. Harismendy O., et al. Genome-wide location of yeast RNA polymerase III transcription machinery. EMBO J. 2003, 22:4738-4747.
40. Roberts D.N., et al. The RNA polymerase III transcriptome revealed by genome-wide localization and activity-occupancy relationships. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:14695-14700.
41. Geiduschek E.P., Kassavetis G.A. The RNA polymerase III transcription apparatus. J. Mol. Biol. 2001, 310:1-26.
42. Carter R., Drouin G. The increase in the number of subunits in eukaryotic RNA polymerase III relative to RNA polymerase II is due to the permanent recruitment of general transcription factors. Mol. Biol. Evol. 2010, 27:1035-1043.
43. Olsten M.E., Litchfield D.W. Order or chaos? An evaluation of the regulation of protein kinase CK2. Biochem. Cell Biol. 2004, 82:681-693.
44. French A.C., et al. Development of a stabilized form of the regulatory CK2beta subunit that inhibits cell proliferation. J. Biol. Chem. 2007, 282:29667-29677.
45. Duncan J.S., Litchfield D.W. Too much of a good thing: the role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2. Biochim. Biophys. Acta 2008, 1784:33-47.
46. Litchfield D.W. Protein kinase CK2: structure, regulation and role in cellular decisions of life and death. Biochem. J. 2003, 369:1-15.
47. White R.J., et al. Cell cycle regulation of RNA polymerase III transcription. Mol. Cell. Biol. 1995, 15:6653-6662.
48. Lin C.Y., et al. CK2-mediated stimulation of Pol I transcription by stabilization of UBF-SL1 interaction. Nucleic Acids Res. 2006, 34:4752-4766.
49. Bierhoff H., et al. Phosphorylation by casein kinase 2 facilitates rRNA gene transcription by promoting dissociation of TIF-IA from elongating RNA polymerase I. Mol. Cell. Biol. 2008, 28:4988-4998.