The "neutral" hydrolysis of simple carboxylic esters in water and the rate enhancements produced by acetylcholinesterase and other carboxylic acid esterases

Journal of the American Chemical Society

Volumn 133, Issue 35, 2011, Pages 13821-13823

  Wolfenden, Richard ^a   Yuan, Yang ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINESTERASE; ACID-CATALYZED HYDROLYSIS; BASE-CATALYZED HYDROLYSIS; CARBOXYLIC ESTERS; ELEVATED TEMPERATURE; ETHYL ACETATES; NEUTRAL HYDROLYSIS; RATE ENHANCEMENT; THERMODYNAMIC ACTIVATION PARAMETERS;

CARBOXYLIC ACIDS; CATALYSIS; ESTERS; RATE CONSTANTS;

HYDROLYSIS;

ACETIC ACID ETHYL ESTER; ACETYLCHOLINE; ACETYLCHOLINESTERASE; CARBOXYLESTERASE; WATER;

ARTICLE; BIOCATALYSIS; EEL; HYDROLYSIS; NEUTRAL HYDROLYSIS; NONHUMAN; THERMODYNAMICS;

ACETIC ACID; ACETYLCHOLINE; ACETYLCHOLINESTERASE; ANIMALS; CARBOXYLIC ACIDS; ELECTROPHORUS; ESTERASES; ESTERS; HYDROLYSIS; KINETICS; THERMODYNAMICS; WATER;

EID: 80052331797     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja204116a     Document Type: Article

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