Peculiarity of epilepsy in elderly people: A review;Particularités de l'epilepsie chez les sujets agés: Revue

West African Journal of Medicine

Volumn 29, Issue 6, 2010, Pages 365-372

  Sanya, E O ^a  

^a UNIVERSITY OF ILORIN   (Nigeria)

Author keywords

Diagnosis; Elderly; Epilepsy; Review; Seizure

Indexed keywords

ALBUMIN; CARBAMAZEPINE; CYTOCHROME P450 3A4; ETIRACETAM; GABAPENTIN; LAMOTRIGINE; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; TIAGABINE; TOPIRAMATE; VALPROIC ACID; ANTICONVULSIVE AGENT;

ADD ON THERAPY; ALBUMIN BLOOD LEVEL; ALZHEIMER DISEASE; ANTICONVULSANT THERAPY; ANXIETY; ATAXIA; BEHAVIOR DISORDER; BLOOD DYSCRASIA; BLURRED VISION; BONE MARROW SUPPRESSION; BRAIN TUMOR; CENTRAL NERVOUS SYSTEM INFECTION; CEREBROSPINAL FLUID ANALYSIS; CEREBROVASCULAR ACCIDENT; CLINICAL FEATURE; COCHRANE LIBRARY; COGNITIVE DEFECT; COMORBIDITY; CONFUSION; DEPRESSION; DIFFERENTIAL DIAGNOSIS; DIPLOPIA; DIZZINESS; DROWSINESS; DRUG INDUCED HEADACHE; DRUG MECHANISM; DRUG TOLERABILITY; EPILEPSY; EPILEPTOGENESIS; ERYTHEMA; FOCAL EPILEPSY; GINGIVA HYPERTROPHY; GRAND MAL SEIZURE; HAIR LOSS; HALLUCINATION; HEAD INJURY; HEART ARRHYTHMIA; HEPATITIS; HUMAN; HYPONATREMIA; HYPOTENSION; IMPOTENCE; IRRITABILITY; KIDNEY FAILURE; LIVER FAILURE; LIVER METABOLISM; MEMORY DISORDER; NAUSEA; NAUSEA AND VOMITING; NEPHROLITHIASIS; NERVE CELL; NEUROPATHY; NYSTAGMUS; OSTEOMALACIA; PANCREATITIS; PANCYTOPENIA; PRESCRIPTION; PSYCHOSIS; QT PROLONGATION; QUALITY OF LIFE; RASH; REVIEW; RHINITIS; RISK FACTOR; SEDATION; SEIZURE; SENESCENCE; SIDE EFFECT; SOMNOLENCE; STEVENS JOHNSON SYNDROME; STROKE; THROMBOCYTOPENIA; TREMOR; WEIGHT GAIN; WEIGHT REDUCTION; AGED; AGING; DEGENERATIVE DISEASE; DRUG INTERACTION; INCIDENCE; PHYSIOLOGY; PSYCHOLOGICAL ASPECT;

AGED; AGED, 80 AND OVER; AGING; ANTICONVULSANTS; COMORBIDITY; DRUG INTERACTIONS; EPILEPSY; HUMANS; INCIDENCE; NEURODEGENERATIVE DISEASES; STROKE;

EID: 80052325206     PISSN: 0189160X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (51)

1. Lowenstein DH. Seizures and epilepsy. In: Kasper DL, Braunwald E, Fauci AS, Hauser SL, Longo DL, Jameson JL, eds. Harrison's Principles of Internal Medicine 16th ed. McGraw-Hills, 2005: pp 2348-23.
2. Glass TA, Mendes de Leon CF, Marottoli RA, Kaplan L, George LK, Gold DT. Population based study of social and productive activities as predictors of survival among elderly Americans. B M J. 1999; 319: 478-483.
3. Stefan LS. Brodie MJ. Epilepsy in the elderly people. Lancet 2000; 355: 1441-1446.
4. Hauser WA, Annegers JF, Kurland LT. The incidence of epilepsy and unprovoked seizures in Rochester, Minnesota, 1935-84. Epilepsia 1993; 34: 453-468.
5. World Health Organisation (WHO). World Health Report 2004; changing History (Annex1). Geneva: WHO 2004.
6. Andrew K, Brocklehurst JC. The implications of demographic changes on resources allocation. J R Coll Physicians Lond 1985; 19: 109-111.
7. Nigeria Population Commission. 1991 Population census of the Federal Republic of Nigeria. Analytical report at the national level. www.population. gov.ng (October 2007)
8. Sanya EO, Akande TM, Opadijo G, Olarinoye JK, Bojuwoye BJ. Pattern and outcome of medical admission of elderly patients seen at the University of Ilorin Teaching Hospital, Ilorin. Afr J Med Med Sci 2008; 37: 375-381.
9. Kotsopoulos IAW, Merode T, Kessels FG, de Krom MC, Knottnerus JA. Systematic review and meta-analysis of incidence studies of epilepsy and unprovoked seizures. Epilepsia. 2002; 43: 1402-1409.
10. Cloyd J, Hauser W, Towne A, Ramsay R, Mattson R, Gilliann F. Epidemiological and medical aspects of epilepsy in the elderly. Epilepsy Res 2006; 68: S39-48.
11. Court A, Breteler MMB, Meinardi H, Howser WA, Hofman A. Prevalence of epilepsy in the elderly: The Rotterdam study. Epilepsia. 1996; 37: 141-147.
12. Pryor FM, Ramsay RE, Rowan AJ. Epilepsy in older adults: update from the VA Cooperative study. Epilepsia 2002; 43: 165-166.
13. Wu YW, Shek DW, Garcia PA, Zha OS, John SC. Incidence and mortality of generalized convulsive status epilepticus in Cali-fornia. Neurology 2002; 58: 1070-1076.
14. Osuntokun BO, Adeuja AOG, Nottidge VA, Bademosi O, Olumide A, Ige O. Prevalence of epilepsies in Nigeria Africans: a community-based study. Epilepsia 1987; 28: 272-279.
15. Annergers JF, Rocca WA, Hauser WA. Causes of epilepsy: Contributions of the Rochester epidemiology project. Mayo Clin Proc. 1996; 71: 570-575.
16. Benbir G, Ince B, Bozluolcay M. The epidemiology of post-stroke epilepsy according to stroke subtypes. Acta Neurol Scand 2006; 114: 8-12.
17. Bladin CF, Alexandrov AV, Bellavance A, Bornstein N, Chambers B, Coté R. Seizures after stroke: a prospective multicenter study. Arch Neurol 2000; 57: 1617-1622.
18. Claassen J, Peery S, Kreiter KT, Hirsch LJ, Du EY, Connolly ES. Predictors and clinical impact of epilepsy after subarachnoid hemorrhage. Neurology 2003; 60: 208-214.
19. Cleary P, Shorvon S, Tallis R. Late-onset seizures as a predictor of subsequent stroke. Lancet. 2004; 363: 1184-1186.
20. DeReuck J, Goethals M, Clerks I, Van Maele G, De Clerk M. EEG findings after a cerebral territorial infarct in patients who develop early- and late- onset seizures. Eur Neurol 2006; 55: 209-13.
21. Kwan J. Wood E. Antiepileptic drugs for the primary and secondary prevention of seizures after stroke. Cochrane Database Syst Rev 2010; 20: CD 0005398.
22. Amatniek JC, Hauser WA, Castillo-Castaneda C, Jacobs DM, Marder K, Bell K. Incidence and predictors of seizures in patients with Alzheimer's disease. Epilepsia. 2006; 47: 867-872.
23. Mendez MF, Catanzaro P, Doss RC, Arguello R, Frey WH. Seizures in Alzheimer's disease: clinicopathologic study. J Geriatr Psychiatry Neurol. 1994; 7: 230-233.
24. Lynam LM, Lyons MK, Drazkowski JF, Sirven JI, Noe KH, Zimmerman RS. Frequency of seizures in patients with newly diagnosed brain tumours: a retrospective review. Clin Neurol Neurosurg. 2007; 109: 634-638.
25. Wen PY, Schiff D, Kesari S, Drappatz J, Girjas DC, Doherty L. Medical management of patients with brain tumours. J Neurooncol. 2006; 80: 313-332.
26. Odebode OT, Sanya EO. Outcome of early posttraumatic seizure: an experience in Nigeria. Nig J Clin Pract 2008; 11: 193-198.
27. Agrawal A, Timothy I, Pandit L, Manju M. et al. Post traumatic epilepsy: an overview. Clin Neurol Neurosurg 2006; 108: 433-439.
28. Lowenstein DH. Recent advances related to basic mechanisms of epileptogenesis. Epilepsy Res Suppl 1996; 11: 45-60.
29. Annergers JF, Coan SP. The risks of epilepsy after traumatic brain injury. Seizure 2000; 9: 453-457.
30. Brodie MJ, Kwan P. Epilepsy in elderly people. BMJ 2005; 331: 1317-1322.
31. Sheth RD, Drazkowski JF, Sirven JI, Gidal BE, Hermann BP. Protracted ictal confusion in elderly patients. Arch Neurol 2006; 63: 529-532.
32. Leppik IE, Birnbaum A. Epilepsy in the elderly. Sem Neurol. 2002; 22: 309-319.
33. Marson A, Jacoby A, Johnson A, Kim L, Gamble C, Chadwick D. Immediate versus deferred antiepileptic drug treatment for early epilepsy and single seizure: a randomised controlled trial. Lancet 2005; 365: 2007-2013.
34. Muller M, Marson AG, Williamson PR. Oxcarbazepine versus phenytoin mono-therapy for epilepsy. Cochrane Data- base Syst Rev 2006 19; 2: CD003615.
35. Perecei E, berlowitz D, Birnbaum A, Cloyd JC, Gerrard J, Hanlon JT. Pharmacological and clinical aspects of antiepileptic drug use in the elderly. Epilepsy Res 2006; 68: 49-63.
36. Ahmed SN, Siddiqi ZS. Antiepileptic drugs and liver disease. Seizure 2006; 15: 156-164
37. Cumbo E, Ligori LD. Levetiracetam, lamotrigine and phenobarbital in patients with epileptic seizures and Alzheimer's disease. Epilepsy behave 2010
38. Rowan AJ, Ramsay RE, Collins JF, Pryor F, Boardman KD, Uthman BM. New onset geriatric epilepsy. A ran- domized study of gabapentin, lamotri- gine, and carbamazepine. Neurology 2005; 64: 1868-1873.
39. Merritt HH, Putnam TJ. Sodium diphenyl hydantoinate in the treatment of convulsive disorders. JAMA 1938; 111: 1068-73.
40. Leppik IE. Treatment of epilepsy in the elderly. Epilepsy Currents 2001; 1: 46-47.
41. Mattson RH, Cramer JA, Collins JF. Comparison of carbamazepine, pheno-barbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures. N Engl J Med 1985; 313: 145-151.
42. Tudur SC, Marson AG, Williamson PR, et al. Carbamazepine versus pheno-barbitone monotherapy for epilepsy. Cochrane Database Syst Rev. 2003; 1: CD001904.
43. Bryson SM, Verma N, Scott PJW. Pharmacokinetics of valproic acid in young and elderly subjects. Br J Clin Pharmacol 1983; 16: 104-105.
44. Yildirim K, Deniz O, Gureser G, Karatay, S, Ugur M, Erdal A. Gabapentin monotherapy in patients with chronic radiculopathy: the efficacy and impact on life quality. J Back Musculo- skelet Rehabil 2009; 22: 17-20.
45. Evans BK, Kustra RO, Hammer AE. Assessment of tolerability in elderly patients: changing to lamotrigine therapy. Am Geritric Pharmacother 2007; 5: 112-119.
46. Schachter, S. C., Vazquez, B., Fisher, R. S. et al. Double-blind randomised, placebo-controlled, monotherapy trial for partial seizures. Neurology 1999; 52: 732-737.
47. Sachdeo R., Edwards K, Hasegawa H, et al. Safety and efficacy of oxcarbazepine 1200 mg/day in patients with recent onset partial epilepsy. Neurology 1999; 52: A391.
48. van Heiningen PN, Eve MD, Oosterhuis B, Jonkman JH, de Bruin H, Hulsman JA. The influence of age on the pharmacokinetics of the antiepileptic agent oxcarbazepine. Clin Pharmacol Ther 1991; 50: 410-9.
49. Gaitatzis A, Carroll K, Majeed A, Sander WJ. The epidemiology of the co-morbidity of epilepsy in the general population. Epilepsia 2004; 45: 1613-1622.
50. Kanner AM, Nieto JC. Depressive disorders in epilepsy. Neurology 1999; 53: 26-32.
51. Johnson EK, Jones, JE, Seidenberg, Hermann BP. The relative impact of anxiety, depression, and clinical seizure features on health-related quality of life in epilepsy. Epilepsia 2004; 45: 544-550.