Omega-3 fatty acids attenuate constitutive and insulin-induced CD36 expression through a suppression of PPARα/γ activity in microvascular endothelial cells

Thrombosis and Haemostasis

Volumn 106, Issue 3, 2011, Pages 500-510

  Madonna, Rosalinda ^a,b   Salerni, Sara ^a   Schiavone, Deborah ^a   Glatz, Jan F ^c   Geng, Yong Jian ^b   de Caterina, Raffaele ^a,d  

^a UNIVERSITY OF CHIETI   (Italy)

^b TEXAS HEART INSTITUTE   (United States)

^c MAASTRICHT UNIVERSITY   (Netherlands)

^d FONDAZIONE TOSCANA GABRIELE MONASTERIO   (Italy)

Author keywords

Atherosclerosis; CD36; Insulin; Insulin resistance; Omega 3 fatty acids; Type 2 diabetes

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 CHLORO 5 NITROBENZANILIDE; ARACHIDONIC ACID; CD36 ANTIGEN; DOCOSAHEXAENOIC ACID; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ICOSAPENTAENOIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; LINOLEIC ACID; OLEIC ACID; OXIDIZED LOW DENSITY LIPOPROTEIN; PALMITIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; WORTMANNIN;

ANTIGEN EXPRESSION; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INCUBATION TIME; MICROVASCULAR ENDOTHELIAL CELL; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN FUNCTION; PROTEIN TRANSPORT; SKIN CELL; TRANSACTIVATION;

ANDROSTADIENES; ANILIDES; ANTIGENS, CD36; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASES; CELL LINE; DERMIS; ENDOTHELIAL CELLS; FATTY ACIDS, OMEGA-3; FLAVONOIDS; GENE EXPRESSION REGULATION; HUMANS; INSULIN; INSULIN RESISTANCE; OXIDATIVE STRESS; PHOSPHATIDYLINOSITOL 3-KINASES; PPAR ALPHA; PPAR GAMMA; RECEPTORS, SCAVENGER;

EID: 80052319523     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH10-09-0574     Document Type: Article

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