USC-HN2, a new model cell line for recurrent oral cavity squamous cell carcinoma with immunosuppressive characteristics

Oral Oncology

Volumn 47, Issue 9, 2011, Pages 810-817

  Russell, Sarah M ^a   Lechner, Melissa G ^a   Gong, Lucy ^a   Megiel, Carolina ^a   Liebertz, Daniel J ^a   Masood, Rizwan ^a   Correa, Adrian J ^a   Han, Jing ^b   Puri, Raj K ^b   Sinha, Uttam K ^a   Epstein, Alan L ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

Cell line; Head and neck squamous cell carcinoma (HNSCC); Human papillomavirus (HPV); Myeloid derived suppressor cells (MDSC); Tumor immune tolerance

Indexed keywords

CD24 ANTIGEN; CD4 ANTIGEN; CD44V ANTIGEN; CELL SURFACE MARKER; EPIDERMAL GROWTH FACTOR RECEPTOR; FATTY ACID BINDING PROTEIN; FATTY ACID BINDING PROTEIN 5; GENOMIC DNA; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1BETA; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 6; INTERLEUKIN 8; KERATIN; MESSENGER RNA; PROTEIN P53; UNCLASSIFIED DRUG; UVOMORULIN; VASCULOTROPIN; VIRUS DNA;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CASE REPORT; CELL STRAIN; CELL STRAIN SCCL MT 1; CELL STRAIN USC HN 2; CELL ULTRASTRUCTURE; CONTROLLED STUDY; CYTOGENETICS; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN PAPILLOMAVIRUS TYPE 18; HUMAN TISSUE; IMMUNOGENICITY; IMMUNOHISTOCHEMISTRY; IMMUNOMODULATION; IMMUNOPHENOTYPING; IMMUNOSUPPRESSIVE TREATMENT; KARYOTYPING; MOUSE; MOUTH CARCINOMA; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RECURRENT CANCER; REGULATORY T LYMPHOCYTE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA; SUPPRESSOR CELL; UPREGULATION; XENOTRANSPLANTATION;

AGED, 80 AND OVER; ANIMALS; ANTIGEN PRESENTATION; CARCINOMA, SQUAMOUS CELL; CELL LINE; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION PROFILING; HUMANS; MICE; MICE, NUDE; MOUTH MUCOSA; MOUTH NEOPLASMS; NEOPLASM RECURRENCE, LOCAL; TUMOR ESCAPE; TUMOR MARKERS, BIOLOGICAL;

EID: 80052270627     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2011.05.015     Document Type: Article

References (28)

1. S.I. Pai, and W.H. Westra Molecular pathology of head and neck cancer: implications for diagnosis, prognosis, and treatment Annu Rev Pathol 4 2009 49 70
2. A. Jemal, R. Siegel, J. Xu, and E. Ward Cancer Statistics, 2010 CA Cancer J Clin 60 2010 277 300
3. P.K. Goon, M.A. Stanley, J. Ebmeyer, L. Steinsträsser, T. Upile, and W. Jerjes HPV & head and neck cancer: a descriptive update Head Neck Oncol 1 2009 36 43
4. J. Kaur, and R. Ralhan Establishment and characterization of a cell line from smokeless tobacco associated oral squamous cell carcinoma Oral Oncol 39 2003 806 820 (Pubitemid 38373465)
5. J. Han, M. Kioi, W.S. Chu, J.L. Kasperbauer, S.E. Strome, and R.K. Puri Identification of potential therapeutic targets in human head & neck squamous cell carcinoma Head Neck Oncol 1 2009 27
6. M.E. Stadler, M.R. Patel, M.E. Couch, and D.N. Hayes Molecular biology of head and neck cancer: risks and pathways Hematol Oncol Clin N Am 22 2008 1099 1124
7. D.S. Heo, C. Snyderman, S.M. Gollin, S. Pan, E. Walker, and R. Deka Biology, cytogenetics, and sensitivity to immunological effector cells of new head and neck squamous cell carcinoma lines Cancer Res 49 1989 5167 5178
8. C.J. Lin, J.R. Grandis, T.E. Carey, S.M. Gollin, T.L. Whiteside, and W.M. Koch Head and neck squamous cell carcinoma cell lines: established models and rationale for selection Head Neck 29 2007 163 188 (Pubitemid 46167784)
9. Albers AE, Strauss L, Liao T, Hoffmann TK, Kaufmann AM. T cell-tumor interaction directs the development of immunotherapies in head and neck cancer. Clin Dev Immunol. 2010;2010:236378. Epub 2010 Dec 27.
10. T.J. Stewart, and S.I. Abrams How tumours escape mass destruction Oncogene 27 2008 5894 5903
11. M.R. Young Protective mechanisms of head and neck squamous cell carcinomas from immune assault Head Neck 28 2006 462 470 (Pubitemid 43673082)
12. C. Bergmann, L. Strauss, Y. Wang, M.J. Szczepanski, S. Lang, and J.T. Johnson T regulatory type 1 cells in squamous cell carcinoma of the head and neck: mechanisms of suppression and expansion in advanced disease Clin Cancer Res 14 2008 3706 3715
13. A. Issa, T.X. Le, A.N. Shoushtari, J.D. Shields, and M.A. Swartz Vascular endothelial growth factor-C and C-C chemokine receptor 7 in tumor cell-lymphatic cross-talk promote invasive phenotype Cancer Res 69 2009 349 357
14. N.F. Erdem, E.R. Carlson, and D.A. Gerard Characterization of gene expression profiles of 3 different human oral squamous cell carcinoma cell lines with different invasion and metastatic capacities J Oral Maxillofac Surg 66 2008 918 927 (Pubitemid 351514833)
15. J.E. Walsh, D.M. Lathers, A.C. Chi, M.B. Gillespie, T.A. Day, and M.R. Young Mechanisms of tumor growth and metastasis in head and neck squamous cell carcinoma Curr Treat Options Oncol 8 2007 227 228
16. D.M. Lathers, N.J. Achille, and M.R. Young Incomplete Th2 skewing of cytokines in plasma of patients with squamous cell carcinoma of the head and neck Hum Immunol 64 2003 1160 1166 (Pubitemid 37475277)
17. A. Sparano, D.M. Lathers, N. Achille, G.J. Petruzzelli, and M.R. Young Modulation of Th1 and Th2 cytokine profiles and their association with advanced head and neck squamous cell carcinoma Otolaryngol Head Neck Surg 131 2004 573 576 (Pubitemid 39446277)
18. D.J. Liebertz, M.G. Lechner, R. Masood, U.K. Sinha, J. Han, and R.K. Puri Establishment and characterization of a novel head and neck squamous cell carcinoma cell line USC-HN1 Head Neck Oncol 2 2010 5
19. M.G. Lechner, S. Lade, D.J. Liebertz, H.M. Prince, G.S. Brody, and H.R. Webster Breast implant-associated, ALK-negative, T-cell, anaplastic, large-cell lymphoma: Establishment and characterization of a model cell line (TLBR-1) for this newly emerging clinical entity Cancer 117 2011 1478 1489
20. A. Subramanian, P. Tamayo, V.K. Mootha, S. Mukherjee, B.L. Ebert, and M.A. Gillette Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles Proc Natl Acad Sci 102 2005 15545 15550 (Pubitemid 41528093)
21. M. Dai, G.M. Clifford, F. le Calvez, X. Castellsagué, P.J. Snijders, and M. Pawlita IARC Multicenter Oral Cancer Study Group. Human papillomavirus type 16 and TP53 mutation in oral cancer: matched analysis of the IARC multicenter study Cancer Res 64 2004 468 471 (Pubitemid 38120884)
22. M.G. Lechner, D.J. Liebertz, and A.L. Epstein Characterization of cytokine-induced myeloid-derived suppressor cells from normal human peripheral blood mononuclear cells J Immunol 185 2010 2273 2284
23. + myeloid-derived suppressor cell subsets induced from peripheral blood mononuclear cells co-cultured with a diverse set of human tumor cell lines. J Transl Med 2011; in press.
24. M.E. Prince, and L.E. Ailles Cancer stem cells in head and neck squamous cell carcinoma J Clin Oncol 26 2008 2871 2875
25. A. Okamoto, K. Chikamatsu, K. Sakakura, K. Hatsushika, G. Takahashi, and K. Masuyama Expansion and characterization of cancer stem-like cells in squamous cell carcinoma of the head and neck Oral Oncol 45 2009 633 639
26. S.H. Chiou, C.C. Yu, C.Y. Huang, S.C. Lin, C.J. Liu, and T.H. Tsai Positive correlations of Oct-4 and Nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinoma Clin Cancer Res 14 2008 4085 4095
27. W.C. van Staveren, D.Y. Solís, A. Hébrant, V. Detours, J.E. Dumont, and C. Maenhaut Human cancer cell lines: Experimental models for cancer cells in situ? For cancer stem cells? Biochim Biophys Acta 2 2009 92 103
28. K. Chikamatsu, G. Takahashi, K. Sakakura, S. Ferrone, and K. Masuyama Immunoregulatory properties of CD44+ cancer stem-like cells in squamous cell carcinoma of the head and neck Head Neck 33 2011 208 215