Assessment of angiogenesis in osseointegration of a silica-collagen biomaterial using 3D-nano-CT

Acta Biomaterialia

Volumn 7, Issue 10, 2011, Pages 3773-3779

  Alt, Volker ^a   Kögelmaier, Daniela Vera ^a   Lips, Katrin S ^a   Witt, Vera ^a   Pacholke, Sabine ^a   Heiss, Christian ^a   Kampschulte, Marian ^a   Heinemann, Sascha ^b   Hanke, Thomas ^b   Schnettler, Reinhard ^a   Langheinrich, Alexander C ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Angiogenesis; Biomaterial; Imaging; Nano CT

Indexed keywords

ANIMALS; BIOMATERIALS; BLOOD VESSELS; BONE; COLLAGEN; COMPUTERIZED TOMOGRAPHY; DEFECTS; INTEGRATION; SILICA;

ANGIOGENESIS; BONE SUBSTITUTE MATERIALS; COMPLEX PROCESSES; CT IMAGING; IMAGE-BASED; MICRO CT; MICRO/NANO; NANO-CT; NEO-VASCULARIZATION; OSSEOINTEGRATION;

VOLUME FRACTION;

BIOMATERIAL; COLLAGEN; SILICON DIOXIDE;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE; BONE DEFECT; BONE REGENERATION; COMPUTED TOMOGRAPHY SCANNER; COMPUTER ASSISTED TOMOGRAPHY; FEMUR; FRACTURE; HISTOLOGY; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; NANOTECHNOLOGY; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; THREE DIMENSIONAL IMAGING; X RAY;

ANIMALIA; RATTUS;

EID: 80052259002     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2011.06.024     Document Type: Article

References (22)

1. J.M. Kanczler, and R.O. Oreffo Osteogenesis and angiogenesis: the potential for engineering bone Eur Cell Mater 15 2008 100 114 (Pubitemid 351955734)
2. S.A. Clarke, N.L. Hoskins, G.R. Jordan, and D.R. Marsh Healing of an ulnar defect using a proprietary TCP bone graft substitute, JAX, in association with autologous osteogenic cells and growth factors Bone 40 4 2007 939 947 (Pubitemid 46402908)
3. F. Geiger, H. Bertram, I. Berger, H. Lorenz, O. Wall, and C. Eckhardt Vascular endothelial growth factor gene-activated matrix (VEGF165-GAM) enhances osteogenesis and angiogenesis in large segmental bone defects J Bone Miner Res 20 11 2005 2028 2035 (Pubitemid 41532788)
4. D. Kaigler, J.A. Cirelli, and W.V. Giannobile Growth factor delivery for oral and periodontal tissue engineering Expert Opin Drug Deliv 3 5 2006 647 662 (Pubitemid 44383492)
5. A.C. Langheinrich, A. Michniewicz, D.G. Sedding, G. Walker, P.E. Beighley, and W.S. Rau Correlation of vasa vasorum neovascularization and plaque progression in aortas of apolipoprotein E(-/-)/low-density lipoprotein(-/-) double knockout mice Arterioscler Thromb Vasc Biol 26 2 2006 347 352 (Pubitemid 43732198)
6. R.R. Chen, J.K. Snow, J.P. Palmer, A.S. Lin, C.L. Duvall, and R.E. Guldberg Host immune competence and local ischemia affects the functionality of engineered vasculature Microcirculation 14 2 2007 77 88 (Pubitemid 46951111)
7. C.L. Duvall, W.R. Taylor, D. Weiss, and R.E. Guldberg Quantitative microcomputed tomography analysis of collateral vessel development after ischemic injury Am J Physiol Heart Circ Physiol 287 1 2004 H302 H310
8. C.L. Duvall, W.R. Taylor, D. Weiss, A.M. Wojtowicz, and R.E. Guldberg Impaired angiogenesis, early callus formation, and late stage remodeling in fracture healing of osteopontin-deficient mice J Bone Miner Res 22 2 2007 286 297 (Pubitemid 46167799)
9. C.L. Duvall, D. Weiss, S.T. Robinson, F.M. Alameddine, R.E. Guldberg, and W.R. Taylor The role of osteopontin in recovery from hind limb ischemia Arterioscler Thromb Vasc Biol 28 2 2008 290 295 (Pubitemid 351161202)
10. Y. Wang, C. Wan, L. Deng, X. Liu, X. Cao, and S.R. Gilbert The hypoxia-inducible factor alpha pathway couples angiogenesis to osteogenesis during skeletal development J Clin Invest 117 6 2007 1616 1626 (Pubitemid 46871346)
11. P.R. Kuzyk, E.H. Schemitsch, and J.E. Davies A biodegradable scaffold for the treatment of a diaphyseal bone defect of the tibia J Orthop Res 28 4 2010 474 480
12. B. Rai, M.E. Oest, K.M. Dupont, K.H. Ho, S.H. Teoh, and R.E. Guldberg Combination of platelet-rich plasma with polycaprolactone-tricalcium phosphate scaffolds for segmental bone defect repair J Biomed Mater Res A 81 4 2007 888 899 (Pubitemid 46835084)
13. H.F. Dvorak, L.F. Brown, M. Detmar, and A.M. Dvorak Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis Am J Pathol 146 5 1995 1029 1039
14. H.F. Dvorak Angiogenesis: update 2005 J Thromb Haemost 3 8 2005 1835 1842 (Pubitemid 41716570)
15. E. Stolz, M. Yeniguen, M. Kreisel, M. Kampschulte, S. Doenges, and D. Sedding Angioarchitectural changes in subacute cerebral venous thrombosis. A synchrotron-based micro- and nano-CT study Neuroimage 54 3 2011 1881 1886
16. S. Heinemann, C. Heinemann, R. Bernhardt, A. Reinstorf, B. Nies, and M. Meyer Bioactive silica-collagen composite xerogels modified by calcium phosphate phases with adjustable mechanical properties for bone replacement Acta Biomater 5 6 2009 1979 1990
17. A.C. Langheinrich, M. Kampschulte, C. Crossmann, R. Moritz, W.S. Rau, and R.M. Bohle Role of computed tomography voxel size in detection and discrimination of calcium and iron deposits in atherosclerotic human coronary artery specimens J Comput Assist Tomogr 33 4 2009 517 522
18. M. Gossl, N.M. Malyar, M. Rosol, P.E. Beighley, and E.L. Ritman Impact of coronary vasa vasorum functional structure on coronary vessel wall perfusion distribution Am J Physiol Heart Circ Physiol 285 5 2003 H2019 H2026
19. A.C. Langheinrich, A. Michniewicz, D.G. Sedding, B. Lai, S.M. Jorgensen, and R.M. Bohle Quantitative X-ray imaging of intraplaque hemorrhage in aortas of apoE(-/-)/LDL(-/-) double knockout mice Invest Radiol 42 5 2007 263 273 (Pubitemid 46558085)
20. M. Gossl, M. Zamir, and E.L. Ritman Vasa vasorum growth in the coronary arteries of newborn pigs Anat Embryol (Berl) 208 5 2004 351 357 (Pubitemid 39179578)
21. M. Gossl, P.E. Beighley, N.M. Malyar, and E.L. Ritman Role of vasa vasorum in transendothelial solute transport in the coronary vessel wall: a study with cryostatic micro-CT Am J Physiol Heart Circ Physiol 287 5 2004 H2346 H2351
22. A.C. Langheinrich, R.M. Bohle, S. Greschus, N. Hackstein, G. Walker, and S. von Gerlach Atherosclerotic lesions at micro CT: feasibility for analysis of coronary artery wall in autopsy specimens Radiology 231 3 2004 675 681 (Pubitemid 38668082)