Detection of HIV-1 RNA/DNA and CD4 mRNA in feces and urine from chronic HIV-1 infected subjects with and without anti-retroviral therapy

AIDS Research and Therapy

Volumn 6, Issue , 2009, Pages

  Chakrabarti, Ayan K ^a   Caruso, Lori ^a   Ding, Ming ^a   Shen, Chengli ^a   Buchanan, William ^a   Gupta, Phalguni ^a   Rinaldo, Charles R ^a   Chen, Yue ^a  

^a UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; CD4 ANTIGEN; VIRUS DNA; VIRUS MESSENGER RNA; VIRUS RNA;

ARTICLE; CHRONIC DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; FECES; FECES ANALYSIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; INTESTINE LYMPHATIC TISSUE; MALE; PATHOGENESIS; PHYLOGENY; PRIORITY JOURNAL; URINALYSIS; URINE; VIRUS DETECTION; VIRUS ENVELOPE; VIRUS LOAD;

EID: 80052257037     PISSN: None     EISSN: 17426405     Source Type: Journal    
DOI: 10.1186/1742-6405-6-20     Document Type: Article

References (32)

1. Schieferdecker HL, Ullrich R, Hirseland H, Zeitz M. T cell differentiation antigens on lymphocytes in the human intestinal lamina propria. J Immunol 1992, 149:2816-2822.
2. Brenchley JM, Schacker TW, Ruff LE, Price DA, Taylor JH, Beilman GJ, et al. CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract. J Exp Med 2004, 200:749-759. 10.1084/jem.20040874, 2211962, 15365096.
3. Mehandru S, Poles MA, Tenner-Racz K, Horowitz A, Hurley A, Hogan C, et al. Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract. J Exp Med 2004, 200:761-770. 10.1084/jem.20041196, 2211967, 15365095.
4. Guadalupe M, Reay E, Sankaran S, Prindiville T, Flamm J, McNeil A, Dandekar S. Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy. J Virol 2003, 77:11708-11717. 10.1128/JVI.77.21.11708-11717.2003, 229357, 14557656.
5. Pope M, Haase AT. Transmission, acute HIV-1 infection and the quest for strategies to prevent infection. Nat Med 2003, 9:847-852. 10.1038/nm0703-847, 12835704.
6. Veazey RS, DeMaria M, Chalifoux LV, Shvetz DE, Pauley DR, Knight HL, et al. Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection. Science 1998, 280:427-431. 10.1126/science.280.5362.427, 9545219.
7. McCune JM. The dynamics of CD4+ T-cell depletion in HIV disease. Nature 2001, 410:974-979. 10.1038/35073648, 11309627.
8. Hoek L, Boom R, Goudsmit J, Snijders F, Sol CJ. Isolation of human immunodeficiency virus type 1 (HIV-1) RNA from feces by a simple method and difference between HIV-1 subpopulations in feces and serum. J Clin Microbiol 1995, 33:581-588. 227994, 7751361.
9. Hoek L, Sol CJ, Maas J, Lukashov VV, Kuiken CL, Goudsmit J. Genetic differences between human immunodeficiency virus type 1 subpopulations in faeces and serum. J Gen Virol 1998, 79(Pt 2):259-267.
10. Hoek L, Sol CJ, Snijders F, Bartelsman JF, Boom R, Goudsmit J. Human immunodeficiency virus type 1 RNA populations in faeces with higher homology to intestinal populations than to blood populations. J Gen Virol 1996, 77(Pt 10):2415-2425. 10.1099/0022-1317-77-10-2415, 8887472.
11. Shepard RN, Schock J, Robertson K, Shugars DC, Dyer J, Vernazza P, et al. Quantitation of human immunodeficiency virus type 1 RNA in different biological compartments. J Clin Microbiol 2000, 38:1414-1418. 86455, 10747117.
12. Miles BJ, Melser M, Farah R, Markowitz N, Fisher E. The urological manifestations of the acquired immunodeficiency syndrome. J Urol 1989, 142:771-773.
13. Rao TK, Filippone EJ, Nicastri AD, Landesman SH, Frank E, Chen CK, Friedman EA. Associated focal and segmental glomerulosclerosis in the acquired immunodeficiency syndrome. N Engl J Med 1984, 310:669-673. 10.1056/NEJM198403153101101, 6700641.
14. Carbone L, D'Agati V, Cheng JT, Appel GB. Course and prognosis of human immunodeficiency virus-associated nephropathy. Am J Med 1989, 87:389-395. 10.1016/S0002-9343(89)80819-8, 2801729.
15. Cao Y, Friedman-Kien AE, Chuba JV, Mirabile M, Hosein B. IgG antibodies to HIV-1 in urine of HIV-1 seropositive individuals. Lancet 1988, 1:831-832. 10.1016/S0140-6736(88)91696-0, 2895351.
16. Hashida S, Hashinaka K, Ishikawa S, Ishikawa E. More reliable diagnosis of infection with human immunodeficiency virus type 1 (HIV-1) by detection of antibody IgGs to pol and gag proteins of HIV-1 and p24 antigen of HIV-1 in urine, saliva, and/or serum with highly sensitive and specific enzyme immunoassay (immune complex transfer enzyme immunoassay): a review. J Clin Lab Anal 1997, 11:267-286. 10.1002/(SICI)1098-2825(1997)11:5<267::AID-JCLA5>3.0.CO;2-4, 9292394.
17. Li JJ, Huang YQ, Poiesz BJ, Zaumetzger-Abbot L, Friedman-Kien AE. Detection of human immunodeficiency virus type 1 (HIV-1) in urine cell pellets from HIV-1-seropositive individuals. J Clin Microbiol 1992, 30:1051-1055. 265222, 1583100.
18. Li JJ, Friedman-Kien AE, Huang YQ, Mirabile M, Cao YZ. HIV-1 DNA proviral sequences in fresh urine pellets from HIV-1 seropositive persons. Lancet 1990, 335:1590-1591. 10.1016/0140-6736(90)90056-B, 1972506.
19. Folks TM, Powell D, Lightfoote M, Koenig S, Fauci AS, Benn S, et al. Biological and biochemical characterization of a cloned Leu-3- cell surviving infection with the acquired immune deficiency syndrome retrovirus. J Exp Med 1986, 164:280-290. 10.1084/jem.164.1.280, 2188205, 3014036.
20. Breitbart M, Hewson I, Felts B, Mahaffy JM, Nulton J, Salamon P, Rohwer F. Metagenomic analyses of an uncultured viral community from human feces. J Bacteriol 2003, 185:6220-6223. 10.1128/JB.185.20.6220-6223.2003, 225035, 14526037.
21. Zhang T, Breitbart M, Lee WH, Run JQ, Wei CL, Soh SW, et al. RNA viral community in human feces: prevalence of plant pathogenic viruses. PLoS Biol 2006, 4:e3. 10.1371/journal.pbio.0040003, 1310650,1310650, 16336043.
22. Sodora DL, Silvestri G. Immune activation and AIDS pathogenesis. Aids 2008, 22:439-446. 10.1097/QAD.0b013e3282f2dbe7, 18301056.
23. Brenchley JM, Paiardini M, Knox KS, Asher AI, Cervasi B, Asher TE, et al. Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections. Blood 2008, 112:2826-2835. 10.1182/blood-2008-05-159301, 2556618, 18664624.
24. Douek D. HIV disease progression: immune activation, microbes, and a leaky gut. Top HIV Med 2007, 15:114-117.
25. Paiardini M, Frank I, Pandrea I, Apetrei C, Silvestri G. Mucosal immune dysfunction in AIDS pathogenesis. AIDS Rev 2008, 10:36-46.
26. Loitsch SM, Shastri Y, Stein J. Stool test for colorectal cancer screening--it's time to move!. Clin Lab 2008, 54:473-484.
27. van Marle G, Gill MJ, Kolodka D, McManus L, Grant T, Church DL. Compartmentalization of the gut viral reservoir in HIV-1 infected patients. Retrovirology 2007, 4:87. 10.1186/1742-4690-4-87, 2217557, 18053211.
28. Bull ME, Learn GH, McElhone S, Hitti J, Lockhart D, Holte S, et al. Monotypic human immunodeficiency virus type 1 genotypes across the uterine cervix and in blood suggest proliferation of cells with provirus. J Virol 2009, 83:6020-6028. 10.1128/JVI.02664-08, 2687376, 19339344.
29. Diem K, Nickle DC, Motoshige A, Fox A, Ross S, Mullins JI, et al. Male genital tract compartmentalization of human immunodeficiency virus type 1 (HIV). AIDS Res Hum Retroviruses 2008, 24:561-571. 10.1089/aid.2007.0115, 18426336.
30. Philpott S, Burger H, Tsoukas C, Foley B, Anastos K, Kitchen C, Weiser B. Human immunodeficiency virus type 1 genomic RNA sequences in the female genital tract and blood: compartmentalization and intrapatient recombination. J Virol 2005, 79:353-363. 10.1128/JVI.79.1.353-363.2005, 538688, 15596829.
31. Chen MF, Westmoreland S, Ryzhova EV, Martin-Garcia J, Soldan SS, Lackner A, Gonzalez-Scarano F. Simian immunodeficiency virus envelope compartmentalizes in brain regions independent of neuropathology. J Neurovirol 2006, 12:73-89. 10.1080/13550280600654565, 16798669.
32. Harrington PR, Connell MJ, Meeker RB, Johnson PR, Swanstrom R. Dynamics of simian immunodeficiency virus populations in blood and cerebrospinal fluid over the full course of infection. J Infect Dis 2007, 196:1058-1067. 10.1086/520819, 17763329.