The feasibility of cryo In-SEM Raman microspectroscopy

Journal of Microscopy

Volumn 244, Issue 2, 2011, Pages 122-128

  Hazekamp, J ^a,b   Reed, M G ^b   Howard, C V ^b   van Apeldoorn, A A ^c   Otto, C ^c  

^a UNILEVER RESEARCH VLAARDINGEN   (Netherlands)

^b UNIVERSITY OF ULSTER   (United Kingdom)

^c UNIVERSITY OF TWENTE   (Netherlands)

Author keywords

Cryo; Cryo SEM; Microspectroscopy; Raman; SEM

Indexed keywords

CROSSLINKING; CRYOGENICS; POLYSTYRENES; RAMAN SCATTERING; SCANNING ELECTRON MICROSCOPY;

AMBIENTS; CRYO; CRYO-SCANNING; CRYO-SCANNING ELECTRON MICROSCOPE; MICRO SPECTROSCOPY; RAMAN; RAMAN MICROSPECTROSCOPY; SCANNING ELECTRON MICROSCOPE; SCANNING ELECTRONS;

SUGAR (SUCROSE);

POLYSTYRENE; SUCROSE;

ARTICLE; CHEMISTRY; COOLING; CROSS LINKING; CRYSTALLIZATION; ELECTRON TOMOGRAPHY; ENVIRONMENTAL TEMPERATURE; FEASIBILITY STUDY; FREEZE DRYING; FREEZING; HEATING; LOW TEMPERATURE; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; RAMAN SPECTROMETRY; SCANNING ELECTRON MICROSCOPY; WATER VAPOR;

EID: 80052255822     PISSN: 00222720     EISSN: 13652818     Source Type: Journal    
DOI: 10.1111/j.1365-2818.2011.03515.x     Document Type: Article

References (17)

1. Aksenov, Y.Y., Reinders, E.G.J., Greve, J., Blitterswijk, C.A. van Bruijn, J.D. de & Otto, C. (2000) Integration of a confocal Raman microscope in an electron microscope. Proc. SPIE. 4164, 90-96.
2. Aksenov, Y.Y., Apeldoorn, A.A., van Bruijn, J.D. van, Blitterswijk, C.A. van, Greve, J. & Otto, C. (2002) Combined confocal Raman microscope with scanning electron microscope: a parallel analysis of inorganic and organic materials. Microsc. Microanal. 8(2), 1386-1387.
3. Aksenov, Y.Y., Apeldoorn, A.A. van, Bruijn, J.D. van, Blitterswijk, C.A. van, Greve, J. & Otto, C. (2003) Combined confocal Raman microscope with scanning electron microscope; degradation of the bio-degradable polymers. Proceedings of the International Conference on Raman Spectroscopy 193. Boedapest, Hungary. Wiley, London, UK.
4. Amer, M.S. (2009) Raman Spectroscopy for Soft Matter Applications. John Wiley & Sons Inc., New Jersey.
5. Anger P., Feltz A., Berghaus T. & Meixner A.J. (2003) Near-field and confocal surface-enhanced resonance Raman spectroscopy at cryogenic temperatures. J. Microsc. 209, 162-166.
6. Apeldoorn, A.A. van, Aksenov Y., Stigter M., et al. (2005) Parallel high-resolution confocal Raman SEM analysis of inorganic and organic bone matrix constituents. J. R. Soc. Interface 2, 39-45.
7. Cavalier, A. Spehner, D. & Humbel, B.M. (2010) The Handbook of Cryo-Preparation Methods for Electron Microscopy. CRC Press, Boca Raton, FL, U.S.A.
8. Dubochet J., Lepault J., Freeman R., Berriman J.A. & Homo J.C. (1982) Electron microscopy of frozen water and aqueous solutions. J. Microsc. 128, 219-237.
9. Dubochet J., Adrian M., Chang J.J., Homo J.C., Lepault J., McDowall A.W. & Schultz P. (1988) Cryo-electron microscopy of vitrified specimens. Q. Rev. Biophys. 21, 129-228.
10. Echlin, P. (1991) Ice crystal damage and radiation effects in relation to microscopy and analysis at low temperatures. J. Microsc. 161(1), 159-170.
11. Echlin, P. (1992) Low-Temperature Microscopy and Analysis. Plenum Press, New York.
12. Gilkey, J.C. & Staehelin, L.A. (1986) Advances in ultrarapid freezing for the preservation of cellular ultrastructure. J. Electron Microsc. Tech. 3, 177-210.
13. Mendelovici, E., Frost R.L. & Kloprogge Th. (2000) Cryogenic Raman spectroscopy of glycerol. J. Raman Spectrosc. 31, 1121-1126.
14. Sivakumar, T.C., Chew, H.A.M. & Johari, G.P. (1978) Effect of pressure on the Raman spectrum of ice. Nature 275, 524-525.
15. Tokuyasu, K.T. (1973) A technique for ultramicrotomy of cell suspensions and tissues. J. Cell Biol. 57, 551-565.
16. Van Harreveld, A. & Crowell, J. (1964) Electron microscopy after rapid freezing on a metal surface and substitution fixation. Anat. Record 149, 381-385.
17. Worobiec, A., Potgieter-Vermaak, S., Brooker, A., Darchuk, L., Stefaniak, E. & Van Grieken, R. (2010). Interfaced SEM/EDX and micro-Raman Spectrometry for characterisation of heterogeneous environmental particles-fundamental and practical challenges. Microchem. J. 94, 65-72.