Gross overestimation of total allowable error based on biological variation

Clinical Chemistry

Volumn 57, Issue 9, 2011, Pages 1334-1336

  Oosterhuis, Wytze P ^a  

^a Sittard Geleen Heerlen   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CREATINE KINASE;

ACCURACY; ANALYTICAL PARAMETERS; BIOLOGICAL VARIATION; CALCULATION; LABORATORY; LETTER; PRACTICE GUIDELINE; QUALITY CONTROL; REFERENCE VALUE; SYSTEMATIC ERROR; THEORETICAL MODEL; TOTAL ALLOWABLE ERROR;

BIAS (EPIDEMIOLOGY); CLINICAL CHEMISTRY TESTS; CREATINE KINASE; DATA INTERPRETATION, STATISTICAL; HUMANS; MODELS, STATISTICAL; QUALITY CONTROL; UNCERTAINTY;

EID: 80052247980     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2011.165308     Document Type: Letter

References (5)

1. Westgard QC. Desirable specifications for total error, imprecision, and bias, derived from intraand inter-individual biologic variation. http://www.westgard.com/biodatabase1.htm (Accessed March 2011).
2. Stöckl D, Baadenhuijsen H, Fraser CG, Libeer JC, Petersen PH, Ricós C. Desirable routine analytical goals for quantities assayed in serum. Eur J Clin Chem Clin Biochem 1995;33:157-69.
3. Gowans EMS, Hyltoft Petersen P, Blaabjerg O, Horder M. Analytical goals for the acceptance of common reference intervals for laboratories throughout a geographical area. Scand J Clin Lab Invest 1988;48:757- 64.
4. Solberg HE. International Federation of Clinical Chemistry (IFCC) Expert Panel on Theory of Reference Values. The theory of reference values. Part 5. Statistical treatment of collected reference values: determination of reference limits. J Clin Chem Clin Biochem 1987;25:645-56.
5. Fraser CG, Hyltoft Petersen P. Quality goals in external quality assessment are best based on biology. Scand J Clin Lab Invest 1993;53 (Suppl 212):8 -9.