The Pivotal Role of Insulin-Like Growth Factor I in Normal Mammary Development

Endocrinology and Metabolism Clinics of North America

Volumn 40, Issue 3, 2011, Pages 461-471

  Kleinberg, David L ^a,b   Barcellos Hoff, Mary Helen ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Ductal morphogenesis; Estradiol; IGF I; Progesterone; TGF

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR; GROWTH HORMONE; PROGESTERONE; PROGESTERONE RECEPTOR; PROLACTIN; SOMATOMEDIN C; STEROID HORMONE;

BREAST DEVELOPMENT; HORMONE ACTION; HORMONE RECEPTOR INTERACTION; HUMAN; LACTATION; LUTEAL PHASE; MOLECULAR INTERACTION; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; PUBERTY; REVIEW; SIGNAL TRANSDUCTION; STEROIDOGENESIS; TISSUE GROWTH;

ANIMALS; BREAST NEOPLASMS; CARCINOMA; FEMALE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MAMMARY GLANDS, ANIMAL; MAMMARY GLANDS, HUMAN; MODELS, BIOLOGICAL; PREGNANCY;

EID: 80052243977     PISSN: 08898529     EISSN: 15584410     Source Type: Journal    
DOI: 10.1016/j.ecl.2011.06.001     Document Type: Review

References (56)

1. Allen E., Francis B.F., Robertson L.L., et al. The hormone of the ovarian follicle; its localization and action in test animals, and additional points bearing upon the internal secretion of the ovary. Am J Anat 1924, 34:133-181.
2. Stricker S., Grueter F. Action du lobe anterieur de l'hypophyse sur la montee laiteuse. Compt Rend Soc Biol 1928, 99:1978-1980. [in French].
3. Wilhelmi A.E. Comparative biochemistry of growth hormone from ox, pig, horse and sheep pituitaries. Henry Ford Hospital International Symposium on the Hypophyseal Growth Hormone: nature and actions 1955, 59-69. McGraw-Hill, New York. R.W. Smith, O.H. Gaebler, C.N. Long (Eds.).
4. Turner C.W., Frank A.H. The effect of the ovarian hormones theelin and corporin upon the growth of the mammary gland of the rabbit 1932, vol. 174. Research Bulletin Missouri Agricultural Experiment Station, p. 1-28.
5. Kleinberg D.L., Ruan W. IGF-I, GH, and sex steroid effects in normal mammary gland development. J Mammary Gland Biol Neoplasia 2008, 13:353-360.
6. Reece R.P., Turner C.W., Hill R.T. Mammary gland development in the hypophysectomized albino rat. Proc Soc Exp Biol Med 1936, 34:204-217.
7. Gardner W.U. Growth of the mammary gland in hypophysectomized mice. Proc Soc Exp Biol Med 1940, 45:835-837.
8. Li C.H., Evans H.M., Simpson M.E. Isolation and properties of the anterior hypophyseal growth hormone. J Biol Chem 1945, 159:353-366.
9. Li C.H. Growth and adrenocorticotropic hormones of anterior pituitary. Harvey Lect Series 1950, 46:181-217.
10. Li C.H., Moskowitz M. Ultracentrifugation of hypophyseal growth hormone. J Biol Chem 1949, 178:203-205.
11. Lyons W.R., Li C.H., Johnson R.E. The hormonal control of mammary growth and lactation. Recent Prog Horm Res 1958, 14:219-254.
12. Nandi S. Hormonal control of mammogenesis and lactogenesis in the C3H/He Crgl mouse 1959, University of California Press, Berkeley (CA) and Los Angeles.
13. Daniel C.W., Silberstein G.B. Postnatal development of the rodent mammary gland. The mammary gland: development, regulation, and function 1987, 1-36. Plenum Press, New York. M.C. Neville, C.W. Daniel (Eds.).
14. Richert M.M., Schwertfeger K.L., Ryder J.W., et al. An atlas of mouse mammary gland development. J Mammary Gland Biol Neoplasia 2000, 5:227-241.
15. Hinck L., Silberstein G.B. Key stages in mammary gland development: the mammary end bud as a motile organ. Breast Cancer Res 2005, 7:245-251.
16. Silberstein G.B. Postnatal mammary gland morphogenesis. Microsc Res Tech 2001, 52:155-162.
17. Howlin J., McBryan J., Martin F. Pubertal mammary gland development: insights from mouse models. J Mammary Gland Biol Neoplasia 2006, 11:283-297.
18. Sternlicht M.D. Key stages in mammary gland development: the cues that regulate ductal branching morphogenesis. Breast Cancer Res 2006, 8:201.
19. Humphreys R.C. Programmed cell death in the terminal endbud. J Mammary Gland Biol Neoplasia 1999, 4:213-220.
20. Daniel C.W., Robinson S., Silberstein G.B. The role of TGF-beta in patterning and growth of the mammary ductal tree. J Mammary Gland Biol Neoplasia 1996, 1:331-341.
21. Silberstein G.B., Van Horn K., Hrabeta-Robinson E., et al. Estrogen-triggered delays in mammary gland gene expression during the estrous cycle: evidence for a novel timing system. J Endocrinol 2006, 190:225-239.
22. Anderson T.J., Battersby S., King R.J.B., et al. Oral contraceptive use influences resting breast proliferation. Hum Pathol 1989, 20:1139-1144.
23. Kleinberg D.L., Wood T.L., Furth P.A., et al. Growth hormone and insulin-like growth factor-I in the transition from normal mammary development to preneoplastic mammary lesions. Endocr Rev 2009, 30:51-74.
24. Bresciani F. Topography of DNA synthesis in the mammary gland of the C3H mouse and its control by ovarian hormones: an autoradiographic study. Cell Tissue Kinet 1968, 1:51-63.
25. Daniel C.W., Silberstein G.B., Strickland P. Direct action of 17 beta-estradiol on mouse mammary ducts analyzed by sustained release implants and steroid autoradiography. Cancer Res 1987, 47:6052-6057.
26. Christov K., Swanson S.M., Guzman R.C., et al. Kinetics of mammary epithelial cell proliferation in pituitary isografted BALB/c mice. Carcinogenesis 1993, 14:2019-2025.
27. Feldman M., Ruan W., Cunningham B.C., et al. Evidence that the growth hormone receptor mediates differentiation and development of the mammary gland. Endocrinology 1993, 133:1602-1608.
28. Walden P.D., Ruan W., Feldman M., et al. Evidence that the mammary fat pad mediates the action of growth hormone in mammary gland development. Endocrinology 1998, 139:659-662.
29. Wood T.L., Richert M.M., Stull M.A., et al. The insulin-like growth factors (IGFs) and IGF binding proteins in postnatal development of murine mammary glands. J Mammary Gland Biol Neoplasia 2000, 5:31-42.
30. Ruan W., Newman C.B., Kleinberg D.L. Intact and aminoterminally shortened forms of insulin-like growth factor I induce mammary gland differentiation and development. Proc Natl Acad Sci U S A 1992, 89:10872-10876.
31. Ruan W., Kleinberg D.L. Insulin-like growth factor I is essential for terminal end bud formation and ductal morphogenesis during mammary development. Endocrinology 1999, 140:5075-5081.
32. Ruan W., Monaco M.E., Kleinberg D.L. Progesterone stimulates mammary gland ductal morphogenesis by synergizing with and enhancing insulin-like growth factor-I action. Endocrinology 2005, 146:1170-1178.
33. Saji S., Jensen E.V., Nilsson S., et al. Estrogen receptors alpha and beta in the rodent mammary gland. Proc Natl Acad Sci U S A 2000, 97:337-342.
34. Jensen E.V., Cheng G., Palmieri C., et al. Estrogen receptors and proliferation markers in primary and recurrent breast cancer. Proc Natl Acad Sci U S A 2001, 98:15197-15202.
35. Mueller S.O., Clark J.A., Myers P.H., et al. Mammary gland development in adult mice requires epithelial and stromal estrogen receptor alpha. Endocrinology 2002, 143:2357-2365.
36. Shyamala G., Chou Y.C., Louie S.G., et al. Cellular expression of estrogen and progesterone receptors in mammary glands: regulation by hormones, development and aging. J Steroid Biochem Mol Biol 2002, 1655:1-12.
37. Shyamala G., Chou Y.C., Louie S.G., et al. Cellular expression of estrogen and progesterone receptors in mammary glands: regulation by hormones, development and aging. J Steroid Biochem Mol Biol 2002, 80:137-148.
38. Petersen O., Hoyer P., van Deurs B. Frequency and distribution of estrogen receptor-positive cells in normal, nonlactating human breast tissue. Cancer Res 1987, 47:5748-5751.
39. Shyamala G., Schneider W., Guiot M.C. Estrogen dependent regulation of estrogen receptor gene expression in normal mammary gland and its relationship to estrogenic sensitivity. Receptor 1992, 2:121-128.
40. Clarke R.B., Howell A., Potten C.S., et al. Dissociation between steroid receptor expression and cell proliferation in the human breast. Cancer Res 1997, 57:4987-4991.
41. Laidlaw I.J., Clarke R.B., Howell A., et al. The proliferation of normal human breast tissue implanted into athymic nude mice is stimulated by estrogen but not progesterone. Endocrinology 1995, 136:164-171. [see comments].
42. Russo I.H., Russo J. Role of hormones in mammary cancer initiation and progression. J Mammary Gland Biol Neoplasia 1998, 3:49-61.
43. Zeps N., Bentel J.M., Papadimitriou J.M., et al. Estrogen receptor-negative epithelial cells in mouse mammary gland development and growth. Differentiation 1998, 62:221-226.
44. Turgeon J.L., Shyamala G., Waring D.W. PR localization and anterior pituitary cell populations in vitro in ovariectomized wild-type and pr-knockout mice. Endocrinology 2001, 142:4479-4485.
45. Ewan K.B., Oketch-Rabah H.A., Ravani S.A., et al. Proliferation of estrogen receptor-alpha-positive mammary epithelial cells is restrained by transforming growth factor-beta 1 in adult mice. Am J Pathol 2005, 167:409-417.
46. Anderson E. Progesterone receptors-animal models and cell signaling in breast cancer: the role of oestrogen and progesterone receptors in human mammary development and tumorigenesis. Breast Cancer Res 2002, 4:197-201.
47. Ruan W., Catanese V., Wieczorek R., et al. Estradiol enhances the stimulatory effect of insulin-like growth factor-I (IGF-I) on mammary development and growth hormone-induced IGF-I messenger ribonucleic acid. Endocrinology 1995, 136:1296-1302.
48. Kleinberg D.L., Ruan W., Catanese V., et al. Non-lactogenic effects of growth hormone on growth and insulin-like growth factor-I messenger ribonucleic acid of rat mammary gland. Endocrinology 1990, 126:3274-3276.
49. Kleinberg D.L. Endocrinology of lactation. Endocrinology 2006, 3461-3473. Elsevier, Philadelphia. L.J. DeGroot, J.L. Jameson (Eds.).
50. Yee D, Chavez JB, Ruan WF, et al. Inhibition of normal mammary gland development and breast cancer growth by IGFBP1. Proc Am Soc Clin Oncol. Annual Meeting, 2000 [abstract].
51. Lydon J.P., DeMayo F.J., Funk C.R., et al. Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities. Genes Dev 1995, 9:2266-2278.
52. Kleinberg D.L., Ameri P., Singh B. Pasireotide, an IGF-I action inhibitor, prevents growth hormone and estradiol-induced mammary hyperplasia. Pituitary 2011, 14(1):44-52.
53. Ng S.T., Zhou J., Adesanya O.O., et al. Growth hormone treatment induces mammary gland hyperplasia in aging primates. Nat Med 1997, 3:1141-1144.
54. Hadsell D.L., Bonnette S.G. IGF and insulin action in the mammary gland: lessons from transgenic and knockout models. J Mammary Gland Biol Neoplasia 2000, 5:19-30.
55. Bonnette S.G., Hadsell D.L. Targeted disruption of the IGF-I receptor gene decreases cellular proliferation in mammary terminal end buds. Endocrinology 2001, 142:4937-4945.
56. Carboni J.M., Lee A.V., Hadsell D.L., et al. Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor. Cancer Res 2005, 65:3781-3787.