메뉴 건너뛰기




Volumn 12, Issue 9, 2011, Pages 1354-1363

Role of the decreased nitric oxide bioavailability in the vascular complications of diabetes mellitus

Author keywords

Antioxidants; CGMP; Diabetes mellitus; Nitric oxide; Oxidation; Oxidative stress; Thiols; Vascular complications of diabetes mellitus

Indexed keywords

ACETYLCYSTEINE; ALPHA TOCOPHEROL; ANTITHROMBOCYTIC AGENT; ASCORBIC ACID; AVE 9488; CARDIOVASCULAR AGENT; CINACIGUAT; CYCLIC GMP; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FREE RADICAL; GUANYLATE CYCLASE; NITRIC OXIDE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN METABOLITE; S NITROSOGLUTATHIONE; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

EID: 80052240854     PISSN: 13892010     EISSN: 18734316     Source Type: Journal    
DOI: 10.2174/138920111798281054     Document Type: Article
Times cited : (22)

References (114)
  • 2
    • 0024400021 scopus 로고
    • Endothelium-derived relaxing factor is an endogenous vasodilator in man
    • Collier, J.; Vallance, P. Endothelium-derived relaxing factor is an endogenous vasodilator in man. Br. J. Pharmacol., 1989, 97(3), 639-641.
    • (1989) Br. J. Pharmacol , vol.97 , Issue.3 , pp. 639-641
    • Collier, J.1    Vallance, P.2
  • 3
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • Furchgott, R. F.; Zawadski, J. V. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature, 1980, 288, 373-376.
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadski, J.V.2
  • 4
    • 0023198721 scopus 로고
    • Nitric oxide release accounts for the biological activity of endothelial-derived relaxing factor
    • Palmer, R. M. J.; Ferrige, A. G.; Moncada, S. Nitric oxide release accounts for the biological activity of endothelial-derived relaxing factor. Nature, 1987, 327, 524-526.
    • (1987) Nature , vol.327 , pp. 524-526
    • Palmer, R.M.J.1    Ferrige, A.G.2    Moncada, S.3
  • 5
    • 0023505509 scopus 로고
    • Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide
    • Ignarro, L. J.; Buga, G. M.; Wood, K. S.; Byrns, R. E.; Chaudhuri, G. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc. Natl. Acad. Sci. USA, 1987, 84, 9265-9269.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 9265-9269
    • Ignarro, L.J.1    Buga, G.M.2    Wood, K.S.3    Byrns, R.E.4    Chaudhuri, G.5
  • 6
    • 0024390169 scopus 로고
    • Endothelium-derived relaxing and contracting factors
    • Furchgott, R. F.; Vanhoutte, P. M. Endothelium-derived relaxing and contracting factors. FASEB J., 1989, 3(9), 2007-2018.
    • (1989) FASEB J , vol.3 , Issue.9 , pp. 2007-2018
    • Furchgott, R.F.1    Vanhoutte, P.M.2
  • 7
    • 0024537028 scopus 로고
    • Endothelium-derived nitric oxide: Actions and properties
    • Ignarro, L. J. Endothelium-derived nitric oxide: actions and properties. FASEB J., 1989, 3(1), 31-36.
    • (1989) FASEB J , vol.3 , Issue.1 , pp. 31-36
    • Ignarro, L.J.1
  • 8
    • 0028261621 scopus 로고
    • Chronic inhibition of nitric oxide production accelerates neointima formation and impairs endothelial function in hypercholesterolemic rabbits
    • Cayatte, A. J.; Palacino, J. J.; Horten, K.; Cohen, R. A. Chronic inhibition of nitric oxide production accelerates neointima formation and impairs endothelial function in hypercholesterolemic rabbits. Arterioscler. Thromb., 1994, 14(5), 753-759.
    • (1994) Arterioscler. Thromb , vol.14 , Issue.5 , pp. 753-759
    • Cayatte, A.J.1    Palacino, J.J.2    Horten, K.3    Cohen, R.A.4
  • 9
    • 0027325255 scopus 로고
    • Nitric oxide synthase structure and mechanism
    • Marletta, M. A. Nitric oxide synthase structure and mechanism. J. Biol. Chem., 1993, 268, 12231-12234.
    • (1993) J. Biol. Chem , vol.268 , pp. 12231-12234
    • Marletta, M.A.1
  • 11
    • 0028026868 scopus 로고
    • Nitric oxide synthase: Aspects concerning structure and catalysis
    • Marletta, M. A. Nitric oxide synthase: aspects concerning structure and catalysis. Cell, 1994, 78, 927-930.
    • (1994) Cell , vol.78 , pp. 927-930
    • Marletta, M.A.1
  • 12
    • 0029091366 scopus 로고
    • Nitric oxide and its role in the cardiovascular system
    • Loscalzo, J.; Welch, G. Nitric oxide and its role in the cardiovascular system. Prog. Cardiovasc. Dis., 1995, 38, 87-104.
    • (1995) Prog. Cardiovasc. Dis , vol.38 , pp. 87-104
    • Loscalzo, J.1    Welch, G.2
  • 13
    • 0029658586 scopus 로고    scopus 로고
    • Genetic analysis of nitric oxide synthase isoforms: Targeted mutation in mice
    • Huang, P. L.; Fishman, M. C. Genetic analysis of nitric oxide synthase isoforms: targeted mutation in mice. J. Mol. Med., 1996, 74(8), 415-421.
    • (1996) J. Mol. Med , vol.74 , Issue.8 , pp. 415-421
    • Huang, P.L.1    Fishman, M.C.2
  • 14
    • 0032533159 scopus 로고    scopus 로고
    • Arginine metabolism: Nitric oxide and beyond
    • Wu, G.; Morris, S. M. Jr. Arginine metabolism: nitric oxide and beyond. Biochem. J., 1998, 336(Pt 1), 1-17.
    • (1998) Biochem. J , vol.336 , Issue.Pt 1 , pp. 1-17
    • Wu, G.1    Morris Jr., S.M.2
  • 15
    • 0027752805 scopus 로고
    • The L-arginine-nitric oxide pathway
    • Moncada, S.; Higgs, A. The L-arginine-nitric oxide pathway. N. Engl. J. Med., 1993, 329, 2002-2012.
    • (1993) N. Engl. J. Med , vol.329 , pp. 2002-2012
    • Moncada, S.1    Higgs, A.2
  • 16
    • 0036752957 scopus 로고    scopus 로고
    • Plasma amino acid levels with a note on membrane transport: Characteristics, regulation, and metabolic significance
    • Cynober, L. A. Plasma amino acid levels with a note on membrane transport: characteristics, regulation, and metabolic significance. Nutrition, 2002, 18(9), 761-766.
    • (2002) Nutrition , vol.18 , Issue.9 , pp. 761-766
    • Cynober, L.A.1
  • 17
    • 0033843849 scopus 로고    scopus 로고
    • Nitric oxideinduced headache in patients with chronic tension-type headache
    • Ashina, M.; Bendtsen, L.; Jensen, R.; Olesen, J. Nitric oxideinduced headache in patients with chronic tension-type headache. J. Brain, 2000, 123, 1830-1937.
    • (2000) J. Brain , vol.123 , pp. 1830-1937
    • Ashina, M.1    Bendtsen, L.2    Jensen, R.3    Olesen, J.4
  • 18
    • 0024428094 scopus 로고
    • Effects of endotheliumderived nitric oxide on peripheral arteriolar tone in man
    • Vallance, P.; Collier, J.; Moncada, S. Effects of endotheliumderived nitric oxide on peripheral arteriolar tone in man. Lancet, 1989, 2(8670), 997-1000.
    • (1989) Lancet , vol.2 , Issue.8670 , pp. 997-1000
    • Vallance, P.1    Collier, J.2    Moncada, S.3
  • 19
    • 0024300153 scopus 로고
    • L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation
    • Palmer, R. M.; Rees, D. D.; Ashton, D. S.; Moncada, S. L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation. Biochem. Biophys. Res. Commun., 1988, 153(3), 1251-1256.
    • (1988) Biochem. Biophys. Res. Commun , vol.153 , Issue.3 , pp. 1251-1256
    • Palmer, R.M.1    Rees, D.D.2    Ashton, D.S.3    Moncada, S.4
  • 20
    • 0001599370 scopus 로고
    • Role of endotheliumderived nitric oxide in the regulation of blood pressure
    • Rees, D. D.; Palmer, R. M.; Moncada, S. Role of endotheliumderived nitric oxide in the regulation of blood pressure. Proc. Natl. Acad. Sci. USA, 1989, 86(9), 3375-3378.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , Issue.9 , pp. 3375-3378
    • Rees, D.D.1    Palmer, R.M.2    Moncada, S.3
  • 21
    • 0034758378 scopus 로고    scopus 로고
    • Endothelial function and nitric oxide: Clinical relevance
    • Vallance, P.; Chan, N. Endothelial function and nitric oxide: clinical relevance. Heart, 2001, 85(3), 342-350.
    • (2001) Heart , vol.85 , Issue.3 , pp. 342-350
    • Vallance, P.1    Chan, N.2
  • 22
    • 0242322346 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine (ADMA): A novel risk factor for endothelial dysfunction: Its role in hypercholesterolemia
    • Boger, R. H.; Bode-Boger, S. M.; Szuba, A.; Tsao, P. S.; Chan, J. R.; Tangphao, O.; Blaschke, T. F.; Cooke, J. P. Asymmetric dimethylarginine (ADMA): a novel risk factor for endothelial dysfunction: its role in hypercholesterolemia. Circulation, 1998, 98(18), 1842-1847.
    • (1998) Circulation , vol.98 , Issue.18 , pp. 1842-1847
    • Boger, R.H.1    Bode-Boger, S.M.2    Szuba, A.3    Tsao, P.S.4    Chan, J.R.5    Tangphao, O.6    Blaschke, T.F.7    Cooke, J.P.8
  • 23
    • 0032912757 scopus 로고    scopus 로고
    • Reduced urinary excretion of nitric oxide metabolites and increased plasma levels of asymmetrical dimethylarginine in men with essential hypertension
    • Surdacki, A.; Nowicki, M.; Sandmann, J. Reduced urinary excretion of nitric oxide metabolites and increased plasma levels of asymmetrical dimethylarginine in men with essential hypertension. J. Cardiovasc. Pharmacol., 1999, 33, 652-658.
    • (1999) J. Cardiovasc. Pharmacol , vol.33 , pp. 652-658
    • Surdacki, A.1    Nowicki, M.2    Sandmann, J.3
  • 24
    • 0242640310 scopus 로고    scopus 로고
    • Biochemical evidence for impaired nitric oxide synthesis in patients with peripheral arterial occlusive disease
    • Boger, R. H.; Bode-Boger, S. M.; Thiele, W.; Junker, W.; Alexander, K.; Frolich, J. C. Biochemical evidence for impaired nitric oxide synthesis in patients with peripheral arterial occlusive disease. Circulation, 1997, 95, 2068-2074.
    • (1997) Circulation , vol.95 , pp. 2068-2074
    • Boger, R.H.1    Bode-Boger, S.M.2    Thiele, W.3    Junker, W.4    Alexander, K.5    Frolich, J.C.6
  • 25
    • 0842347848 scopus 로고    scopus 로고
    • The emerging role of asymmetric dimethylarginine as a novel cardiovascular risk factor
    • Boger, R. H. The emerging role of asymmetric dimethylarginine as a novel cardiovascular risk factor. Cardiovasc. Res., 2003, 59(4), 824-833.
    • (2003) Cardiovasc. Res , vol.59 , Issue.4 , pp. 824-833
    • Boger, R.H.1
  • 26
    • 0033537633 scopus 로고    scopus 로고
    • Endogenous nitric oxide synthase inhibitor: A novel marker of atherosclerosis
    • Miyazaki, H.; Matsuoka, H.; Cooke, J. P.; Usui, M.; Ueda, S.; Okuda, S.; Imaizumi, T. Endogenous nitric oxide synthase inhibitor: a novel marker of atherosclerosis. Circulation, 1999, 99(9), 1141-1146.
    • (1999) Circulation , vol.99 , Issue.9 , pp. 1141-1146
    • Miyazaki, H.1    Matsuoka, H.2    Cooke, J.P.3    Usui, M.4    Ueda, S.5    Okuda, S.6    Imaizumi, T.7
  • 29
    • 0344052668 scopus 로고    scopus 로고
    • Tetrahydrobiopterin and endothelial nitric oxide synthase activity
    • Cosentino, F.; Luscher, T. F. Tetrahydrobiopterin and endothelial nitric oxide synthase activity. Cardiovasc. Res., 1999, 43, 274-278.
    • (1999) Cardiovasc. Res , vol.43 , pp. 274-278
    • Cosentino, F.1    Luscher, T.F.2
  • 31
    • 61449176167 scopus 로고    scopus 로고
    • Endothelial dysfunction and pathophysiological correlates in atrial fibrillation
    • Guazzi, M.; Arena, R. Endothelial dysfunction and pathophysiological correlates in atrial fibrillation. Heart, 2009, 95(2), 102-106.
    • (2009) Heart , vol.95 , Issue.2 , pp. 102-106
    • Guazzi, M.1    Arena, R.2
  • 32
    • 0023760164 scopus 로고
    • Cytoplasmic calcium response to fluid shear stress in cultured vascular endothelial cells
    • Ando, J.; Komatsuda, T.; Kamiya, A. Cytoplasmic calcium response to fluid shear stress in cultured vascular endothelial cells. In Vitro Cell. Dev. Biol., 1988, 24(9), 871-977.
    • (1988) Vitro Cell. Dev. Biol , vol.24 , Issue.9 , pp. 871-977
    • Ando, J.1    Komatsuda, T.2    Kamiya, A.3
  • 33
    • 0028837365 scopus 로고
    • Calcium responses of endothelial cell monolayers subjected to pulsatile and steady laminar flow differ
    • Helmlinger, G.; Berk, B. C.; Nerem, R.M. Calcium responses of endothelial cell monolayers subjected to pulsatile and steady laminar flow differ. Am. J. Physiol., 1995, 269(2 Pt 1), 367-375.
    • (1995) Am. J. Physiol , vol.269 , Issue.2 Pt 1 , pp. 367-375
    • Helmlinger, G.1    Berk, B.C.2    Nerem, R.M.3
  • 34
    • 0024285834 scopus 로고
    • Haemodynamic shear stress activates a K+ current in vascular endothelial cells
    • Olesen, S. P.; Clapham, D. E.; Davies, P. F. Haemodynamic shear stress activates a K+ current in vascular endothelial cells. Nature, 1988, 331(6152), 168-170.
    • (1988) Nature , vol.331 , Issue.6152 , pp. 168-170
    • Olesen, S.P.1    Clapham, D.E.2    Davies, P.F.3
  • 35
    • 0032696285 scopus 로고    scopus 로고
    • A flowactivated chloride-selective membrane current in vascular endothelial cells
    • Barakat, A. I.; Leaver, E. V.; Pappone, P.A.; Davies, P. F. A flowactivated chloride-selective membrane current in vascular endothelial cells. Circ. Res., 1999, 85 (9), 820-828.
    • (1999) Circ. Res , vol.85 , Issue.9 , pp. 820-828
    • Barakat, A.I.1    Leaver, E.V.2    Pappone, P.A.3    Davies, P.F.4
  • 36
    • 0032489676 scopus 로고    scopus 로고
    • Ca2+- independent activation of the endothelial nitric oxide synthase in response to tyrosine phosphatase inhibitors and fluid shear stress
    • Fleming, I.; Bauersachs, J.; Fisslthaler, B.; Busse, R. Ca2+- independent activation of the endothelial nitric oxide synthase in response to tyrosine phosphatase inhibitors and fluid shear stress. Circ. Res., 1998, 82(6), 686-695.
    • (1998) Circ. Res , vol.82 , Issue.6 , pp. 686-695
    • Fleming, I.1    Bauersachs, J.2    Fisslthaler, B.3    Busse, R.4
  • 37
    • 0033542476 scopus 로고    scopus 로고
    • Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
    • Dimmeler, S.; Fleming, I.; Fisslthaler, B.; Hermann, C.; Busse, R.; Zeiher, A. M. Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature, 1999, 399(6736), 601-605.
    • (1999) Nature , vol.399 , Issue.6736 , pp. 601-605
    • Dimmeler, S.1    Fleming, I.2    Fisslthaler, B.3    Hermann, C.4    Busse, R.5    Zeiher, A.M.6
  • 38
    • 0034089197 scopus 로고    scopus 로고
    • Signalling pathways in vascular endothelium activated by shear stress: Relevance to atherosclerosis
    • Resnick, N.; Yahav, H.; Schubert, S.; Wolfovitz, E.; Shay, A. Signalling pathways in vascular endothelium activated by shear stress: relevance to atherosclerosis. Curr. Opin. Lipidol., 2000, 11(2), 167-177.
    • (2000) Curr. Opin. Lipidol , vol.11 , Issue.2 , pp. 167-177
    • Resnick, N.1    Yahav, H.2    Schubert, S.3    Wolfovitz, E.4    Shay, A.5
  • 39
    • 0000707453 scopus 로고
    • Nitric oxide activates guanylate cyclase and increases guanosine 3':5'-cyclic monophosphate levels in various tissue preparations
    • Arnold, W. P.; Mittal, C. K.; Katsuki, S.; Murad, F. Nitric oxide activates guanylate cyclase and increases guanosine 3':5'-cyclic monophosphate levels in various tissue preparations. Proc. Natl. Acad. Sci. USA, 1977, 74(8), 3203-3207.
    • (1977) Proc. Natl. Acad. Sci. USA , vol.74 , Issue.8 , pp. 3203-3207
    • Arnold, W.P.1    Mittal, C.K.2    Katsuki, S.3    Murad, F.4
  • 40
    • 53249088371 scopus 로고    scopus 로고
    • Nitroglycerin-induced S-nitrosylation and desensitization of soluble guanylyl cyclase contribute to nitrate tolerance
    • Sayed, N.; Kim, D. D.; Fioramonti, X.; Iwahashi, T.; Duran, W. N.; Beuve, A. Nitroglycerin-induced S-nitrosylation and desensitization of soluble guanylyl cyclase contribute to nitrate tolerance. Circ. Res., 2008, 103, 606-614.
    • (2008) Circ. Res , vol.103 , pp. 606-614
    • Sayed, N.1    Kim, D.D.2    Fioramonti, X.3    Iwahashi, T.4    Duran, W.N.5    Beuve, A.6
  • 41
    • 1442330336 scopus 로고    scopus 로고
    • Snitrosylation of endothelial nitric oxide synthase is associated with monomerization and decreased enzyme activity
    • Ravi, K.; Brennan, L.A.; Levic, S.; Ross, P. A.; Black, S. M. Snitrosylation of endothelial nitric oxide synthase is associated with monomerization and decreased enzyme activity. Proc. Natl. Acad. Sci. USA, 2004, 101, 2619-2624.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 2619-2624
    • Ravi, K.1    Brennan, L.A.2    Levic, S.3    Ross, P.A.4    Black, S.M.5
  • 43
    • 14844300857 scopus 로고    scopus 로고
    • S-nitrosylation-dependent inactivation of Akt/protein kinase B in insulin resistance
    • Yasukawa, T.; Tokunaga, E.; Ota, H.; Sugita, H.; Martyn, J.A.; Kaneki, M. S-nitrosylation-dependent inactivation of Akt/protein kinase B in insulin resistance. J. Biol. Chem., 2005, 280, 7511-7518.
    • (2005) J. Biol. Chem , vol.280 , pp. 7511-7518
    • Yasukawa, T.1    Tokunaga, E.2    Ota, H.3    Sugita, H.4    Martyn, J.A.5    Kaneki, M.6
  • 44
    • 0028220671 scopus 로고
    • Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle
    • Bolotina, V.M.; Najibi, S.; Palacino, J.J.; Pagano, P.J.; Cohen, R.A. Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle. Nature, 1994, 368, 850-853.
    • (1994) Nature , vol.368 , pp. 850-853
    • Bolotina, V.M.1    Najibi, S.2    Palacino, J.J.3    Pagano, P.J.4    Cohen, R.A.5
  • 46
    • 75549083692 scopus 로고    scopus 로고
    • Endothelial dysfunction as a target for prevention of cardiovascular disease
    • Versari, D.; Daghini, E.; Virdis, A.; Ghiadoni, L.; Taddei, S. Endothelial dysfunction as a target for prevention of cardiovascular disease. Diabetes Care, 2009, 32(Suppl 2), 314-321.
    • (2009) Diabetes Care , vol.32 , Issue.SUPPL. 2 , pp. 314-321
    • Versari, D.1    Daghini, E.2    Virdis, A.3    Ghiadoni, L.4    Taddei, S.5
  • 47
    • 0033637470 scopus 로고    scopus 로고
    • Endothelial dysfunction in hypercholesterolemia: Mechanisms, pathophysiological importance, and therapeutic interventions
    • Landmesser, U.; Hornig, B.; Drexler, H. Endothelial dysfunction in hypercholesterolemia: mechanisms, pathophysiological importance, and therapeutic interventions. Semin. Thromb. Hemost., 2000, 26(5), 529-537.
    • (2000) Semin. Thromb. Hemost , vol.26 , Issue.5 , pp. 529-537
    • Landmesser, U.1    Hornig, B.2    Drexler, H.3
  • 49
    • 56949103019 scopus 로고    scopus 로고
    • Endothelial dysfunction: Causes and consequences in patients with diabetes mellitus
    • Avogaro, A.; de Kreutzenberg, S.V.; Fadini, G. Endothelial dysfunction: causes and consequences in patients with diabetes mellitus. Diabetes Res. Clin. Pract., 2008, 82(Suppl 2), S94-S101.
    • (2008) Diabetes Res. Clin. Pract , vol.82 , Issue.SUPPL. 2 , pp. 94-101
    • Avogaro, A.1    de Kreutzenberg, S.V.2    Fadini, G.3
  • 50
    • 35748964459 scopus 로고    scopus 로고
    • Association of eNOS Glu298Asp gene polymorphism with essential hypertension in Asian Indians
    • Srivastava, K.; Narang, R.; Sreenivas, V.; Das S.; Dasn N. Association of eNOS Glu298Asp gene polymorphism with essential hypertension in Asian Indians. Clin. Chim. Acta, 2008, 387(1/2), 80-83.
    • (2008) Clin. Chim. Acta , vol.387 , Issue.1-2 , pp. 80-83
    • Srivastava, K.1    Narang, R.2    Sreenivas, V.3    Das, S.4    Dasn, N.5
  • 51
    • 28844488388 scopus 로고    scopus 로고
    • Genetic polymorphisms G894T on the eNOS gene is associated with endothelial function and vWF levels in premature myocardial infarction survivors
    • Antoniades, C.; Tousoulis, D.; Vasiliadou, C.; Pitsavos, C.; Toutouza, M.; Tentolouris, C.; Marinou, K.; Stefanadis, C. Genetic polymorphisms G894T on the eNOS gene is associated with endothelial function and vWF levels in premature myocardial infarction survivors. Int. J. Cardiol., 2006, 107(1), 95-100.
    • (2006) Int. J. Cardiol , vol.107 , Issue.1 , pp. 95-100
    • Antoniades, C.1    Tousoulis, D.2    Vasiliadou, C.3    Pitsavos, C.4    Toutouza, M.5    Tentolouris, C.6    Marinou, K.7    Stefanadis, C.8
  • 52
    • 65949106586 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine (ADMA): An endogenous inhibitor of nitric oxide synthase and a novel cardiovascular risk molecule
    • de Gennaro Colonna, V.; Bianchi, M.; Pascale, V.; Ferrario, P.; Morelli, F.; Pascale, W.; Tomasoni, L.; Turiel, M. Asymmetric dimethylarginine (ADMA): an endogenous inhibitor of nitric oxide synthase and a novel cardiovascular risk molecule. Med. Sci. Monit., 2009, 15 (4), RA91-RA101.
    • (2009) Med. Sci. Monit , vol.15 , Issue.4 , pp. 91-101
    • de Gennaro, C.V.1    Bianchi, M.2    Pascale, V.3    Ferrario, P.4    Morelli, F.5    Pascale, W.6    Tomasoni, L.7    Turiel, M.8
  • 53
    • 41849144894 scopus 로고    scopus 로고
    • Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. superoxide production by eNOS
    • Crabtree, M. J.; Smith, C. L.; Lam, G.; Goligorsky, M. S.; Gross, S. S. Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. superoxide production by eNOS. Am. J. Physiol., 2008, 294(4), H1530-H1540.
    • (2008) Am. J. Physiol , vol.294 , Issue.4 , pp. 1530-1540
    • Crabtree, M.J.1    Smith, C.L.2    Lam, G.3    Goligorsky, M.S.4    Gross, S.S.5
  • 54
    • 33644946470 scopus 로고    scopus 로고
    • Thiol oxidation inhibits nitric oxide-mediated pulmonary artery relaxation and guanylate cyclase stimulation
    • Mingone, C. J.; Gupte, S. A.; Ali, N.; Oeckler, R. A., Wolin, M. S. Thiol oxidation inhibits nitric oxide-mediated pulmonary artery relaxation and guanylate cyclase stimulation. Am. J. Physiol., 2006, 290, L549-L557.
    • (2006) Am. J. Physiol , vol.290 , pp. 549-557
    • Mingone, C.J.1    Gupte, S.A.2    Ali, N.3    Oeckler, R.A.4    Wolin, M.S.5
  • 55
    • 0029682870 scopus 로고    scopus 로고
    • Oxidative damage and tyrosine nitration from peroxynitrite
    • Beckman, J. S. Oxidative damage and tyrosine nitration from peroxynitrite. Chem. Res. Toxicol., 1996, 9(5), 836-844.
    • (1996) Chem. Res. Toxicol , vol.9 , Issue.5 , pp. 836-844
    • Beckman, J.S.1
  • 57
    • 0141615827 scopus 로고    scopus 로고
    • Diabetes and vascular disease: Pathophysiology, clinical consequences, and medical therapy: Part I
    • Creager, M. A.; Luscher, T. F.; Cosentino, F.; Beckman, J. A. Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: Part I. Circulation, 2003, 108 (12), 1527-1532.
    • (2003) Circulation , vol.108 , Issue.12 , pp. 1527-1532
    • Creager, M.A.1    Luscher, T.F.2    Cosentino, F.3    Beckman, J.A.4
  • 58
    • 0037900056 scopus 로고    scopus 로고
    • Pathophysiological implications of insulin resistance on vascular endothelial function
    • Wheatcroft, S. B.; Williams, I. L.; Shah, A. M.; Kearney, M. T. Pathophysiological implications of insulin resistance on vascular endothelial function. Diabet. Med., 2003, 20, 255-268.
    • (2003) Diabet. Med , vol.20 , pp. 255-268
    • Wheatcroft, S.B.1    Williams, I.L.2    Shah, A.M.3    Kearney, M.T.4
  • 59
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis, A. J. Atherosclerosis. Nature, 2000, 407, 233-241.
    • (2000) Nature , vol.407 , pp. 233-241
    • Lusis, A.J.1
  • 61
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • Brownlee, M. Biochemistry and molecular cell biology of diabetic complications. Nature, 2001, 414, 813-820.
    • (2001) Nature , vol.414 , pp. 813-820
    • Brownlee, M.1
  • 62
    • 0026624980 scopus 로고
    • Diseases of the mitochondrial DNA
    • Wallace, D. C. Diseases of the mitochondrial DNA. Annu. Rev. Biochem., 1992, 61, 1175-1212.
    • (1992) Annu. Rev. Biochem , vol.61 , pp. 1175-1212
    • Wallace, D.C.1
  • 63
    • 0025358947 scopus 로고
    • The protonmotive Q cycle
    • Trumpower, B. L. The protonmotive Q cycle. J. Biol. Chem., 1990, 265, 11409-11412.
    • (1990) J. Biol. Chem , vol.265 , pp. 11409-11412
    • Trumpower, B.L.1
  • 64
    • 0031853099 scopus 로고    scopus 로고
    • Substrate and site specificity of hydrogen peroxide generation in mouse mitochondria
    • Kwong, L. K.; Sohal, R. S. Substrate and site specificity of hydrogen peroxide generation in mouse mitochondria. Arch. Biochem. Biophys., 1998, 350, 118-126.
    • (1998) Arch. Biochem. Biophys , vol.350 , pp. 118-126
    • Kwong, L.K.1    Sohal, R.S.2
  • 65
    • 0030729851 scopus 로고    scopus 로고
    • High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria
    • Korshunov, S. S.; Skulachev, V. P.; Starkov, A. A. High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria. FEBS Lett., 1997, 416, 15-18.
    • (1997) FEBS Lett , vol.416 , pp. 15-18
    • Korshunov, S.S.1    Skulachev, V.P.2    Starkov, A.A.3
  • 66
    • 0034710891 scopus 로고    scopus 로고
    • Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation
    • Du, X. L.; Edelstein, D.; Rossetti, L.; Fantus, I. G.; Goldberg, H.; Ziyadeh, F.; Wu, J.; Brownlee, M. Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation. Proc. Natl. Acad. Sci. USA, 2000, 97, 12222-12226.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 12222-12226
    • Du, X.L.1    Edelstein, D.2    Rossetti, L.3    Fantus, I.G.4    Goldberg, H.5    Ziyadeh, F.6    Wu, J.7    Brownlee, M.8
  • 67
    • 0022456638 scopus 로고
    • Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor
    • Rubanyi, G. M.; Vanhoutte, P. M. Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor. Am. J. Physiol., 1986, 250, H822-H827
    • (1986) Am. J. Physiol , vol.250 , pp. 822-827
    • Rubanyi, G.M.1    Vanhoutte, P.M.2
  • 68
    • 33845378793 scopus 로고
    • Reaction of superoxide with nitric oxide to form peroxonitrite in alkaline aqueous solution
    • Blough, N. V.; Zafiriou, O. C. Reaction of superoxide with nitric oxide to form peroxonitrite in alkaline aqueous solution. Inorg. Chem., 1985, 24, 3504-3505
    • (1985) Inorg. Chem , vol.24 , pp. 3504-3505
    • Blough, N.V.1    Zafiriou, O.C.2
  • 69
    • 41349096436 scopus 로고    scopus 로고
    • Nitric oxide, tetrahydrobiopterin, oxidative stress, and endothelial dysfunction in hypertension
    • Schulz, E.; Jansen, T.; Wenzel, P.; Daiber, A.; Munzel, T. Nitric oxide, tetrahydrobiopterin, oxidative stress, and endothelial dysfunction in hypertension. Antioxid. Redox. Signal., 2008, 10, 1115-1126
    • (2008) Antioxid. Redox. Signal , vol.10 , pp. 1115-1126
    • Schulz, E.1    Jansen, T.2    Wenzel, P.3    Daiber, A.4    Munzel, T.5
  • 72
    • 33748312096 scopus 로고    scopus 로고
    • NO-independent stimulators and activators of soluble guanylate cyclase: Discovery and therapeutic potential
    • Evgenov, O. V.; Pacher, P.; Schmidt, P. M.; Hasko, G.; Schmidt, H. H.; Stasch, J. P. NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential. Nat. Rev. Drug. Discov., 2006, 5, 755-768.
    • (2006) Nat. Rev. Drug. Discov , vol.5 , pp. 755-768
    • Evgenov, O.V.1    Pacher, P.2    Schmidt, P.M.3    Hasko, G.4    Schmidt, H.H.5    Stasch, J.P.6
  • 73
    • 0030892215 scopus 로고    scopus 로고
    • Endothelial dysfunction: Clinical implications
    • Drexler, H. Endothelial dysfunction: clinical implications. Prog. Cardiovasc. Dis., 1997, 39 (4), 287-324.
    • (1997) Prog. Cardiovasc. Dis , vol.39 , Issue.4 , pp. 287-324
    • Drexler, H.1
  • 74
    • 0029128672 scopus 로고
    • The role of nitric oxide and other endotheliumderived vasoactive substances in vascular disease
    • Cohen, R. A. The role of nitric oxide and other endotheliumderived vasoactive substances in vascular disease. Prog. Cardiovasc. Dis., 1995, 38(2), 105-128.
    • (1995) Prog. Cardiovasc. Dis , vol.38 , Issue.2 , pp. 105-128
    • Cohen, R.A.1
  • 75
    • 0025832494 scopus 로고
    • Elevated glucose impairs endothelium-dependent relaxation by activating protein kinase C
    • Tesfamariam, B.; Brown, M. L.; Cohen, R. A. Elevated glucose impairs endothelium-dependent relaxation by activating protein kinase C. J. Clin. Invest., 1991, 87(5), 1643-1648.
    • (1991) J. Clin. Invest , vol.87 , Issue.5 , pp. 1643-1648
    • Tesfamariam, B.1    Brown, M.L.2    Cohen, R.A.3
  • 77
    • 0032971418 scopus 로고    scopus 로고
    • Relationship among cholesterol, superoxide anion and endothelium-dependent relaxation in diabetic rats
    • Kobayashi, T.; Kamata, K. Relationship among cholesterol, superoxide anion and endothelium-dependent relaxation in diabetic rats. Eur. J. Pharmacol., 1999, 367(2/3), 213-222.
    • (1999) Eur. J. Pharmacol , vol.367 , Issue.2-3 , pp. 213-222
    • Kobayashi, T.1    Kamata, K.2
  • 78
    • 0028045638 scopus 로고
    • Endothelial dysfunction in mesenteric resistance arteries of diabetic rats: Role of free radicals
    • Diederich, D.; Skopec, J.; Diederich, A.; Dai, F. X. Endothelial dysfunction in mesenteric resistance arteries of diabetic rats: role of free radicals. Am. J. Physiol., 1994, 266(3 Pt 2), H1153-H1161.
    • (1994) Am. J. Physiol , vol.266 , Issue.3 Pt 2 , pp. 1153-1161
    • Diederich, D.1    Skopec, J.2    Diederich, A.3    Dai, F.X.4
  • 80
    • 0032950298 scopus 로고    scopus 로고
    • Enhanced, unaltered and impaired nitric oxidemediated endothelium-dependent relaxation in experimental diabetes mellitus: Importance of disease duration
    • Pieper, G.M. Enhanced, unaltered and impaired nitric oxidemediated endothelium-dependent relaxation in experimental diabetes mellitus: importance of disease duration. Diabetologia, 1999, 42(2), 204-213.
    • (1999) Diabetologia , vol.42 , Issue.2 , pp. 204-213
    • Pieper, G.M.1
  • 81
    • 0030837996 scopus 로고    scopus 로고
    • High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells
    • Cosentino, F.; Hishikawa, K.; Katusic, Z.S.; Luscher, T.F. High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells. Circulation, 1997, 96(1), 25-28.
    • (1997) Circulation , vol.96 , Issue.1 , pp. 25-28
    • Cosentino, F.1    Hishikawa, K.2    Katusic, Z.S.3    Luscher, T.F.4
  • 82
    • 0041025099 scopus 로고    scopus 로고
    • Impairment of endothelium dependent relaxation in the diabetic rat heart: Mechanisms and implications
    • Rosen, P.; Ballhausen, T.; Stockklauser, K. Impairment of endothelium dependent relaxation in the diabetic rat heart: mechanisms and implications. Diabetes Res. Clin. Pract., 1996, 31 (Suppl.), S143-S155.
    • (1996) Diabetes Res. Clin. Pract , vol.31 , Issue.SUPPL. , pp. 143-155
    • Rosen, P.1    Ballhausen, T.2    Stockklauser, K.3
  • 83
    • 0033816515 scopus 로고    scopus 로고
    • The impaired renal vasodilator response attributed to endothelium-derived hyperpolarizing factor in streptozotocin-induced diabetic rats is restored by 5-methyltetrahydrofolate
    • de Vriese, A.S.; Van de Voorde, J.; Blom, H.J.; Vanhoutte, P.M.; Verbeke, M.; Lameire, N.H. The impaired renal vasodilator response attributed to endothelium-derived hyperpolarizing factor in streptozotocin-induced diabetic rats is restored by 5-methyltetrahydrofolate. Diabetologia, 2000, 43(9), 1116-1125.
    • (2000) Diabetologia , vol.43 , Issue.9 , pp. 1116-1125
    • de Vriese, A.S.1    Van de Voorde, J.2    Blom, H.J.3    Vanhoutte, P.M.4    Verbeke, M.5    Lameire, N.H.6
  • 84
    • 0024559857 scopus 로고
    • Impaired neurogenic and endothelium-mediated relaxation of penile smooth muscle from diabetic men with impotence
    • Saenz de Tejada, I.; Goldstein, I.; Azadzoi, K.; Krane, R. J.; Cohen, R. A. Impaired neurogenic and endothelium-mediated relaxation of penile smooth muscle from diabetic men with impotence. N. Engl. J. Med., 1989, 320, 1025-1030.
    • (1989) N. Engl. J. Med , vol.320 , pp. 1025-1030
    • de Tejada, S.I.1    Goldstein, I.2    Azadzoi, K.3    Krane, R.J.4    Cohen, R.A.5
  • 86
    • 0032706783 scopus 로고    scopus 로고
    • Elevated skeletal muscle blood flow in noncomplicated type 1 diabetes mellitus: Role of nitric oxide and sympathetic tone
    • Vervoort, G.; Wetzels, J. F.; Lutterman, J. A.; van Doorn, L. G.; Berden, J. H.; Smits, P. Elevated skeletal muscle blood flow in noncomplicated type 1 diabetes mellitus: role of nitric oxide and sympathetic tone. Hypertension, 1999, 34(5), 1080-1085.
    • (1999) Hypertension , vol.34 , Issue.5 , pp. 1080-1085
    • Vervoort, G.1    Wetzels, J.F.2    Lutterman, J.A.3    van Doorn, L.G.4    Berden, J.H.5    Smits, P.6
  • 87
    • 0023713429 scopus 로고
    • Oxygen free radicals abolish endothelium- dependent relaxation in diabetic rat aorta
    • Pieper, G. M.; Gross, G. J. Oxygen free radicals abolish endothelium- dependent relaxation in diabetic rat aorta. Am. J. Physiol., 1988, 255(4 Pt 2), H825-H833.
    • (1988) Am. J. Physiol , vol.255 , Issue.4 Pt 2 , pp. 825-833
    • Pieper, G.M.1    Gross, G.J.2
  • 88
    • 0027216069 scopus 로고
    • Impairment of coronary vascular reserve and ACh-induced coronary vasodilation in diabetic patients with angiographically normal coronary arteries and normal left ventricular systolic function
    • Nitenberg, A.; Valensi, P.; Sachs, R.; Dali, M.; Aptecar, E.; Attali, J. R. Impairment of coronary vascular reserve and ACh-induced coronary vasodilation in diabetic patients with angiographically normal coronary arteries and normal left ventricular systolic function. Diabetes, 1993, 42(7), 1017-1025.
    • (1993) Diabetes , vol.42 , Issue.7 , pp. 1017-1025
    • Nitenberg, A.1    Valensi, P.2    Sachs, R.3    Dali, M.4    Aptecar, E.5    Attali, J.R.6
  • 89
    • 0027381832 scopus 로고
    • Impaired endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus
    • Johnstone, M. T.; Creager, S. J.; Scales, K. M.; Cusco, J.A.; Lee, B. K.; Creager, M. A. Impaired endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus. Circulation, 1993, 88(6), 2510-2516.
    • (1993) Circulation , vol.88 , Issue.6 , pp. 2510-2516
    • Johnstone, M.T.1    Creager, S.J.2    Scales, K.M.3    Cusco, J.A.4    Lee, B.K.5    Creager, M.A.6
  • 90
    • 0027522119 scopus 로고
    • Inhibition of nitric oxide synthesis in forearm vasculature of insulin-dependent diabetic patients: Blunted vasoconstriction in patients with microalbuminuria
    • Elliott, T. G.; Cockcroft, J. R.; Groop, P. H.; Viberti, G. C.; Ritter, J.M. Inhibition of nitric oxide synthesis in forearm vasculature of insulin-dependent diabetic patients: blunted vasoconstriction in patients with microalbuminuria. Clin. Sci. (Lond.)., 1993, 85(6), 687-693.
    • (1993) Clin. Sci. (Lond.) , vol.85 , Issue.6 , pp. 687-693
    • Elliott, T.G.1    Cockcroft, J.R.2    Groop, P.H.3    Viberti, G.C.4    Ritter, J.M.5
  • 91
    • 0029064154 scopus 로고
    • Noninvasive detection of functional alterations of the arterial wall in IDDM patients with and without microalbuminuria
    • Zenere, B. M.; Arcaro, G.; Saggiani, F.; Rossi, L.; Muggeo, M.; Lechi, A. Noninvasive detection of functional alterations of the arterial wall in IDDM patients with and without microalbuminuria. Diabetes Care, 1995, 18(7), 975-982.
    • (1995) Diabetes Care , vol.18 , Issue.7 , pp. 975-982
    • Zenere, B.M.1    Arcaro, G.2    Saggiani, F.3    Rossi, L.4    Muggeo, M.5    Lechi, A.6
  • 93
    • 0031975594 scopus 로고    scopus 로고
    • Effect of exercise training and food restriction on endothelium-dependent relaxation in the Otsuka Long-Evans Tokushima Fatty rat, a model of spontaneous NIDDM
    • Sakamoto, S.; Minami, K.; Niwa, Y.; Ohnaka, M.; Nakaya, Y.; Mizuno, A.; Kuwajima, M.; Shima, K. Effect of exercise training and food restriction on endothelium-dependent relaxation in the Otsuka Long-Evans Tokushima Fatty rat, a model of spontaneous NIDDM. Diabetes, 1998, 47(1), 82-86.
    • (1998) Diabetes , vol.47 , Issue.1 , pp. 82-86
    • Sakamoto, S.1    Minami, K.2    Niwa, Y.3    Ohnaka, M.4    Nakaya, Y.5    Mizuno, A.6    Kuwajima, M.7    Shima, K.8
  • 94
    • 0031443413 scopus 로고    scopus 로고
    • Therapeutic interventions in endothelial dysfunction: Endothelium as a target organ
    • Cooke, J.P. Therapeutic interventions in endothelial dysfunction: endothelium as a target organ. Clin. Cardiol., 1997, 20(11 Suppl 2), 45-51.
    • (1997) Clin. Cardiol , vol.20 , Issue.11 SUPPL 2 , pp. 45-51
    • Cooke, J.P.1
  • 95
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • The Diabetes Control and Complications Trial Research Group
    • The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N. Engl. J. Med., 1993, 329(14), 977-986.
    • (1993) N. Engl. J. Med , vol.329 , Issue.14 , pp. 977-986
  • 96
    • 0028939363 scopus 로고
    • The effect of cholesterol-lowering and antioxidant therapy on endothelium-dependent coronary vasomotion
    • Anderson, T. J.; Meredith, I. T.; Yeung, A. C.; Frei, B.; Selwyn, A. P.; Ganz, P. The effect of cholesterol-lowering and antioxidant therapy on endothelium-dependent coronary vasomotion. N. Engl. J. Med., 1995, 332(8), 488-493.
    • (1995) N. Engl. J. Med , vol.332 , Issue.8 , pp. 488-493
    • Anderson, T.J.1    Meredith, I.T.2    Yeung, A.C.3    Frei, B.4    Selwyn, A.P.5    Ganz, P.6
  • 97
    • 0030689824 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibition alters nitric oxide and superoxide release in normotensive and hypertensive rats
    • Wiemer, G.; Linz, W.; Hatrik, S.; Scholkens, B. A.; Malinski, T. Angiotensin-converting enzyme inhibition alters nitric oxide and superoxide release in normotensive and hypertensive rats. Hypertension, 1997, 30(5), 1183-1190.
    • (1997) Hypertension , vol.30 , Issue.5 , pp. 1183-1190
    • Wiemer, G.1    Linz, W.2    Hatrik, S.3    Scholkens, B.A.4    Malinski, T.5
  • 98
    • 0031648561 scopus 로고    scopus 로고
    • Diabetes mellitus and vascular lesions
    • Hayoz, D.; Ziegler, T.; Brunner, H. R.; Ruiz, J. Diabetes mellitus and vascular lesions. Metabolism, 1998, 47(12 Suppl 1), 16-19.
    • (1998) Metabolism , vol.47 , Issue.12 SUPPL 1 , pp. 16-19
    • Hayoz, D.1    Ziegler, T.2    Brunner, H.R.3    Ruiz, J.4
  • 99
    • 0027422043 scopus 로고
    • Differences in coronary mortality can be explained by differences in cholesterol and saturated fat intakes in 40 countries but not in France and Finland. A paradox
    • Artaud-Wild, S. M.; Connor, S.L.; Sexton, G.; Connor, W. E. Differences in coronary mortality can be explained by differences in cholesterol and saturated fat intakes in 40 countries but not in France and Finland. A paradox. Circulation, 1993, 88(6), 2771-2779.
    • (1993) Circulation , vol.88 , Issue.6 , pp. 2771-2779
    • Artaud-Wild, S.M.1    Connor, S.L.2    Sexton, G.3    Connor, W.E.4
  • 101
    • 0031977246 scopus 로고    scopus 로고
    • Antioxidant defences are reduced during the oral glucose tolerance test in normal and non-insulin-dependent diabetic subjects
    • Ceriello, A.; Bortolotti, N.; Crescentini, A.; Motz, E.; Lizzio, S.; Russo, A.; Ezsol, Z.; Tonutti, L.; Taboga, C. Antioxidant defences are reduced during the oral glucose tolerance test in normal and non-insulin-dependent diabetic subjects. Eur. J. Clin. Invest., 1998, 28(4), 329-333.
    • (1998) Eur. J. Clin. Invest , vol.28 , Issue.4 , pp. 329-333
    • Ceriello, A.1    Bortolotti, N.2    Crescentini, A.3    Motz, E.4    Lizzio, S.5    Russo, A.6    Ezsol, Z.7    Tonutti, L.8    Taboga, C.9
  • 104
    • 0036834582 scopus 로고    scopus 로고
    • Effects of vitamin E on cardiovascular and microvascular outcomes in high-risk patients with diabetes: Results of the HOPE study and MICRO-HOPE substudy
    • HOPE Study; MICRO-HOPE Study
    • Lonn, E.; Yusuf, S.; Hoogwerf, B.; Pogue, J.; Yi, Q.; Zinman, B.; Bosch, J.; Dagenais, G.; Mann, J. F.; Gerstein, H. C.; HOPE Study; MICRO-HOPE Study. Effects of vitamin E on cardiovascular and microvascular outcomes in high-risk patients with diabetes: results of the HOPE study and MICRO-HOPE substudy. Diabetes Care, 2002, 25(11), 1919-1927.
    • (2002) Diabetes Care , vol.25 , Issue.11 , pp. 1919-1927
    • Lonn, E.1    Yusuf, S.2    Hoogwerf, B.3    Pogue, J.4    Yi, Q.5    Zinman, B.6    Bosch, J.7    Dagenais, G.8    Mann, J.F.9    Gerstein, H.C.10
  • 105
    • 0019322058 scopus 로고
    • Possible involvement of S-nitrosothiols in the activation of guanylate cyclase by nitroso compounds
    • Ignarro, L. J.; Edwards, J. C.; Gruetter, D. Y.; Barry, B. K.; Gruetter, C. A. Possible involvement of S-nitrosothiols in the activation of guanylate cyclase by nitroso compounds. FEBS Lett., 1980, 110(2), 275-278.
    • (1980) FEBS Lett , vol.110 , Issue.2 , pp. 275-278
    • Ignarro, L.J.1    Edwards, J.C.2    Gruetter, D.Y.3    Barry, B.K.4    Gruetter, C.A.5
  • 106
    • 0031800116 scopus 로고    scopus 로고
    • Oral administration of the antioxidant, N-acetylcysteine, abrogates diabetes-induced endothelial dysfunction
    • Pieper, G. M.; Siebeneich, W. Oral administration of the antioxidant, N-acetylcysteine, abrogates diabetes-induced endothelial dysfunction. J. Cardiovasc. Pharmacol., 1998, 32(1), 101-105.
    • (1998) J. Cardiovasc. Pharmacol , vol.32 , Issue.1 , pp. 101-105
    • Pieper, G.M.1    Siebeneich, W.2
  • 107
    • 0031033321 scopus 로고    scopus 로고
    • Acute amelioration of diabetic endothelial dysfunction with a derivative of the nitric oxide synthase cofactor, tetrahydrobiopterin
    • Pieper, G. M. Acute amelioration of diabetic endothelial dysfunction with a derivative of the nitric oxide synthase cofactor, tetrahydrobiopterin. J. Cardiovasc. Pharmacol., 1997, 29(1), 8-15.
    • (1997) J. Cardiovasc. Pharmacol , vol.29 , Issue.1 , pp. 8-15
    • Pieper, G.M.1
  • 108
    • 0035117433 scopus 로고    scopus 로고
    • Administration of Glutathione In Patients With Type 2 Diabetes Mellitus Increases the Platelet Constitutive Nitric Oxide Synthase Activity and Reduces PAI-1
    • Martina, V.; Bruno, G. A.; Zumpano, E.; Origlia, C.; Quaranta, L.; Pescarmona, G. P. Administration of glutathione in patients with type 2 diabetes mellitus increases the platelet constitutive nitric oxide synthase activity and reduces PAI-1. J. Endocrinol. Invest., 2001, 24 (1), 37-41.
    • (2001) J. Endocrinol. Invest , vol.24 , Issue.1 , pp. 37-41
    • Martina, V.1    Bruno, G.A.2    Zumpano, E.3    Origlia, C.4    Quaranta, L.5    Pescarmona, G.P.6
  • 109
    • 70349503662 scopus 로고    scopus 로고
    • N-acetylcysteine is able to reduce the oxidation status and the endothelial activation after a high-glucose content meal in patients with Type 2 diabetes mellitus
    • Masha, A.; Brocato, L.; Dinatale, S.; Mascia, C.; Biasi, F.; Martina, V. N-acetylcysteine is able to reduce the oxidation status and the endothelial activation after a high-glucose content meal in patients with Type 2 diabetes mellitus. J. Endocrinol. Invest., 2009, 32(4), 352-356.
    • (2009) J. Endocrinol. Invest , vol.32 , Issue.4 , pp. 352-356
    • Masha, A.1    Brocato, L.2    Dinatale, S.3    Mascia, C.4    Biasi, F.5    Martina, V.6
  • 111
    • 0028824722 scopus 로고
    • Thiol dependence of nitric oxide synthase
    • Hofmann, H.; Schmidt, H. H. Thiol dependence of nitric oxide synthase. Biochemistry, 1995, 34, 13443-13452.
    • (1995) Biochemistry , vol.34 , pp. 13443-13452
    • Hofmann, H.1    Schmidt, H.H.2
  • 112
    • 0032521146 scopus 로고    scopus 로고
    • L-2-oxothiazolidine-4-carboxylic acid reverses endothelial dysfunction in patients with coronary artery disease
    • Vita, J. A.; Frei, B.; Holbrook, M.; Gokce, N.; Leaf, C.; Keaney, J. F. L-2-oxothiazolidine-4-carboxylic acid reverses endothelial dysfunction in patients with coronary artery disease. J. Clin. Invest., 1998, 101, 1408-1414.
    • (1998) J. Clin. Invest , vol.101 , pp. 1408-1414
    • Vita, J.A.1    Frei, B.2    Holbrook, M.3    Gokce, N.4    Leaf, C.5    Keaney, J.F.6
  • 114
    • 0037046214 scopus 로고    scopus 로고
    • Mechanisms of increased vascular superoxide production in human diabetes mellitus: Role of NAD(P)H oxidase and endothelial nitric oxide synthase
    • Guzik, T. J.; Mussa, S.; Gastaldi, D.; Sadowski, J.; Ratnatunga, C.; Pillai, R.; Channon, K. M. Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthase. Circulation, 2002, 105, 1656-1662.
    • (2002) Circulation , vol.105 , pp. 1656-1662
    • Guzik, T.J.1    Mussa, S.2    Gastaldi, D.3    Sadowski, J.4    Ratnatunga, C.5    Pillai, R.6    Channon, K.M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.