A New Twist on Clock Protein Phosphorylation: A Conformational Change Leads to Protein Degradation

Molecular Cell

Volumn 43, Issue 5, 2011, Pages 695-697

  Menet, Jerome S ^a   Rosbash, Michael ^a  

^a BRANDEIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASEIN KINASE I; CASEIN KINASE II; FREQUENCY PROTEIN; PER2 PROTEIN; PROTEIN; TRANSCRIPTION FACTOR CLOCK; UNCLASSIFIED DRUG;

ALPHA HELIX; BINDING SITE; CELLULAR DISTRIBUTION; CIRCADIAN RHYTHM; CONFORMATIONAL TRANSITION; MISSENSE MUTATION; MUTATION; NEUROSPORA; NONHUMAN; PHENOTYPE; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; SHORT SURVEY;

NEUROSPORA;

EID: 80052227822     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2011.08.015     Document Type: Short Survey

References (11)

1. Baker C.L., Kettenbach A.N., Loros J.J., Gerber S.A., Dunlap J.C. Mol. Cell 2009, 34:354-363.
2. Chiu J.C., Vanselow J.T., Kramer A., Edery I. Genes Dev. 2008, 22:1758-1772.
3. Chiu J.C., Ko H.W., Edery I. Cell 2011, 145:357-370.
4. Kim E.Y., Ko H.W., Yu W., Hardin P.E., Edery I. Mol. Cell. Biol. 2007, 27:5014-5028.
5. Konopka R.J., Benzer S. Proc. Natl. Acad. Sci. USA 1971, 68:2112-2116.
6. Mehra A., Baker C.L., Loros J.J., Dunlap J.C. Trends Biochem. Sci. 2009, 34:483-490.
7. Nawathean P., Stoleru D., Rosbash M. Mol. Cell. Biol. 2007, 27:5002-5013.
8. Querfurth C., Diernfellner A.C.R., Gin E., Malzahn E., Höfer T., Brunner M. Mol. Cell 2011, 43:713-722. this issue.
9. Rutila J.E., Edery I., Hall J.C., Rosbash M. J. Neurogenet. 1992, 8:101-113.
10. Tang C.T., Li S., Long C., Cha J., Huang G., Li L., Chen S., Liu Y. Proc. Natl. Acad. Sci. USA 2009, 106:10722-10727.
11. Toh K.L., Jones C.R., He Y., Eide E.J., Hinz W.A., Virshup D.M., Ptácek L.J., Fu Y.H. Science 2001, 291:1040-1043.