Skeletal scintigraphy with 18F-NaF PET for the evaluation of bone pain in children

American Journal of Roentgenology

Volumn 197, Issue 3, 2011, Pages 713-719

  Drubach, Laura A ^a   Connolly, Susan A ^a   Palmer III, Edwin L ^b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

18F NaF; Bone scintigraphy; Pediatric imaging; PET; Sports medicine; Stress fractures; Trauma

Indexed keywords

MEDRONATE TECHNETIUM TC 99M; SODIUM FLUORIDE F 18; DIAGNOSTIC AGENT; FLUORIDE SODIUM; FLUORINE;

BONE CANCER; BONE INJURY; BONE METASTASIS; BONE PAIN; BONE SCINTISCANNING; CHILD; COMPUTER ASSISTED TOMOGRAPHY; DIAGNOSTIC ACCURACY; HUMAN; IMAGE QUALITY; PLASMA PROTEIN BINDING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIATION ABSORPTION; RADIOISOTOPE DISTRIBUTION; REVIEW; RIB FRACTURE; STRESS FRACTURE; ADOLESCENT; ADULT; ARTICLE; BACKACHE; BONE; DIFFERENTIAL DIAGNOSIS; FEMALE; MALE; METHODOLOGY; SCINTISCANNING;

ADOLESCENT; BACK PAIN; BONE AND BONES; CHILD; DIAGNOSIS, DIFFERENTIAL; FEMALE; FLUORINE RADIOISOTOPES; HUMANS; MALE; POSITRON-EMISSION TOMOGRAPHY; SODIUM FLUORIDE; YOUNG ADULT;

EID: 80052225587     PISSN: 0361803X     EISSN: 15463141     Source Type: Journal    
DOI: 10.2214/AJR.11.6670     Document Type: Review

References (14)

1. Blau M, Nagler W, Bender MA. Fluorine-18: a new isotope for bone scanning. J Nucl Med 1962; 3:332-334
2. Park-Holohan SJ, Blake GM, Fogelman I. Quantitative studies of bone using (18)F-fluoride and (99m)Tc-methylene diphosphonate: evaluation of renal and whole-blood kinetics. Nucl Med Commun 2001; 22:1037-1044 (Pubitemid 32783456)
3. Blau M, Ganatra R, Bender MA. 18F-fluoride for bone imaging. Semin Nucl Med 1972; 2:31-37
4. Segall G, Delbeke D, Stabin MG, et al. SNM. SNM practice guideline for sodium 18F-fluoride PET/CT bone scans 1.0. J Nucl Med 2010; 51:1813-1820
5. Czernin J, Satyamurthy N, Schiepers C. Molecular mechanisms of bone 18F-NaF deposition. J Nucl Med 2010; 51:1826-1829
6. Grant FD, Fahey FH, Packard AB, Davis RT, Alavi A, Treves ST. Skeletal PET with 18F-fluoride: applying new technology to an old tracer. J Nucl Med 2008; 49:68-78
7. Bhargava P, Hanif M, Nash C. Whole-body F-18 sodium fluoride PET-CT in a patient with renal cell carcinoma. Clin Nucl Med 2008; 33:894-895
8. Hetzel M, Arslandemir C, Konig HH, et al. F-18 NaF PET for detection of bone metastases in lung cancer: accuracy, cost-effectiveness, and impact on patient management. J Bone Miner Res 2003; 18:2206-2214 (Pubitemid 37463314)
9. Schirrmeister H, Buck A, Guhlmann A, Reske SN. Anatomical distribution and sclerotic activity of bone metastases from thyroid cancer assessed with F-18 sodium fluoride positron emission tomography. Thyroid 2001; 11:677-683 (Pubitemid 32701589)
10. Gamie S, El-Maghraby T. The role of PET/CT in evaluation of facet and disc abnormalities in patients with low back pain using (18)F-fluoride. Nucl Med Rev Cent East Eur 2008; 11:17-21
11. Schirrmeister H, Rentschler M, Kotzerke J, Diederichs CG, Reske SN. Imaging of the normal skeletal system with 18F Na-PET compared with conventional skeletal scintigraphy using Tc99m-MDP (in German). Rofo 1998; 168:451-456
12. Lim R, Fahey FH, Drubach LA, Connolly LP, Treves ST. Early experience with fluorine-18 sodium fluoride bone PET in young patients with back pain. J Pediatr Orthop 2007; 27:277-282 (Pubitemid 46573178)
13. Drubach LA, Johnston PR, Newton AW, Perez- Rossello JM, Grant FD, Kleinman PK. Skeletal trauma in child abuse: detection with 18F-NaF PET. Radiology 2010; 255:173-181
14. 18F-fluoride with positron emission tomography reveals damage- and time-dependent responses to fatigue loading in the rat ulna. Bone 2006; 39: 229-236