Direct observations of conformational distributions of intrinsically disordered p53 peptides using UV Raman and explicit solvent simulations

Journal of Physical Chemistry A

Volumn 115, Issue 34, 2011, Pages 9520-9527

  Xiong, Kan ^a   Zwier, Matthew C ^a   Myshakina, Nataliya S ^a   Burger, Virginia M ^a   Asher, Sanford A ^a   Chong, Lillian T ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGLE DISTRIBUTION; CONFORMATIONAL DISTRIBUTION; CONFORMATIONAL SELECTION; EXPERIMENTAL MEASUREMENTS; EXPLICIT SOLVENTS; HELICAL CONFORMATION; HELICAL CONTENT; ISOTOPICALLY LABELED; MOLECULAR DYNAMICS SIMULATIONS; N-TERMINALS; PEPTIDE FRAGMENTS; QUANTITATIVE AGREEMENT; SIMULATION RESULT; TIME-SCALES; TUMOR SUPPRESSORS; UNBOUND STATE; UV-RAMAN; UV-RESONANCE RAMAN SPECTROSCOPY; WILD TYPES;

AMINO ACIDS; CONFORMATIONS; MOLECULAR DYNAMICS; RAMAN SPECTROSCOPY;

PEPTIDES;

LEUCINE; MDM2 PROTEIN, HUMAN; PEPTIDE FRAGMENT; PROLINE; PROTEIN MDM2; PROTEIN P53; SERINE; SOLVENT;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; GENETICS; HUMAN; METABOLISM; PHYSICAL CHEMISTRY; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; RAMAN SPECTROMETRY;

BINDING SITES; CHEMISTRY, PHYSICAL; COMPUTER SIMULATION; HUMANS; LEUCINE; MODELS, MOLECULAR; PEPTIDE FRAGMENTS; PROLINE; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-MDM2; SERINE; SOLVENTS; SPECTRUM ANALYSIS, RAMAN; TUMOR SUPPRESSOR PROTEIN P53;

EID: 80052224142     PISSN: 10895639     EISSN: 15205215     Source Type: Journal    
DOI: 10.1021/jp112235d     Document Type: Article

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