Autoimmune lymphoproliferative disorder in an adult patient

Journal of Postgraduate Medicine

Volumn 57, Issue 2, 2011, Pages 131-133

  Desai, N K ^a   Morkhandikar, S ^a   Bajpai, S ^a   Pazare, A R ^a  

^a KEM HOSPITAL   (India)

Author keywords

Autoimmune lymphoproliferation; Castleman's disease; double negative lymphocytes; lymphadenopathy

Indexed keywords

ANTIBIOTIC AGENT; CORTICOSTEROID; HEMOGLOBIN; IMMUNOGLOBULIN G; PREDNISOLONE; STEROID;

ADULT; ADULT DISEASE; ARTICLE; AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME; CASE REPORT; CD4 CD8 RATIO; CERVICAL LYMPH NODE; CERVICAL LYMPHADENOPATHY; COMPUTER ASSISTED TOMOGRAPHY; CYTOPENIA; ECHOGRAPHY; EPISTAXIS; ERYTHROCYTE CONCENTRATE; ERYTHROCYTE SEDIMENTATION RATE; FEVER; FLOW CYTOMETRY; FOLLOW UP; HOSPITAL DISCHARGE; HUMAN; HUMAN TISSUE; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; INDIA; LEUKOCYTE COUNT; LYMPH NODE BIOPSY; LYMPHADENITIS; LYMPHOMA; MALAISE; MALE; PALLOR; PETECHIA; REMISSION; SPLENOMEGALY; THROMBOCYTE COUNT; THROMBOCYTE TRANSFUSION;

AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME; EPISTAXIS; FEVER; HUMANS; LYMPH NODES; MALE; MIDDLE AGED;

EID: 80052217818     PISSN: 00223859     EISSN: 09722823     Source Type: Journal    
DOI: 10.4103/0022-3859.81873     Document Type: Article

References (13)

1. Greiner T, Armitage JO, Gross TG. Atypical lymphoproliferative diseases. Hematology Am Soc Hematol Educ Program. 2000: 1:133-146.
2. Sneller MC, Wang J, Dale JK, Strober W, Middelton LA, Chori Y, et al. Clinical, immunologic, and genetic features of an autoimmune lymphoproliferative syndrome associated with abnormal lymphocyte apoptosis. Blood 1997;89:1341-8. (Pubitemid 27079998)
3. Fisher GH, Rosenberg FJ, Straus SE, Dale JK, Middleton LA, Lin AY, et al. Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome. Cell 1995;81:936-46.
4. Rieux-Laucat F, Le Deist F, Hivroz C, Roberts IA, Debatin KM, Fischer A, et al. Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. Science 1995;268:1347.
5. Jackson CE, Puck JM. Autoimmune lymphoproliferative syndrome, a disorder of apoptosis. Curr Opin Pediatr 1999;11:521-7.
6. Dianzani U, Bragardo M, DiFranco D, Alliaudi C, Scagni P, Buonfiglio D, et al. Deficiency of the Fas apoptosis pathway without Fas gene mutations in pediatric patients with autoimmunity/ lymphoproliferation. Blood 1997;89:2871-9. (Pubitemid 27172574)
7. Straus SE, Jaffe ES, Puck JM, Dale JK, Elkon KB, Rösen-Wolff A, et al. The development of Lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis Blood 2001;98:194-200.
8. John MJ, Rajasekhar JR, Mathews V. Autoimmune lymphoproliferative syndrome (ALPS): A rare cause of immune cytopenia. Indian Pediatr 2008;45:148-50. (Pubitemid 351340735)
9. Oliveira JB, Bleesing JJ, Dianzani U, Fleisher TA, Jaffe ES, Lenardo MJ, et al. Revised diagnostic criteria and classification for the autoimmune lymphoproliferative syndrome (ALPS): Report from the 2009 NIH International Workshop. Blood 2010;116:35-40
10. Rao VK, Price S, Perkins K, Aldridge P, Tretler J, Davis J, et al. Use of Rituximab for refractory cytopenias associated with autoimmune lymphoproliferative syndrome (ALPS). Pediatr Blood Cancer 2009;52:847-52.
11. Teachey DT, Greiner R, Seif A, Attiyeh E, Bleesing J, Choi J, et al. Treatment with sirolimus results in complete responses inpatients with autoimmune lymphoproliferative syndrome. Br J Haematol. 2009;145:101.
12. Le Deist F. Autoimmune lymphoproliferative syndrome. Orphanet encyclopedia. October 2004;1-4.
13. Worth A, Thrasher AJ, Gaspar HB. Autoimmune lymphoproliferative syndrome: Molecular basis of disease and clinical phenotype. Br J Hematol 2006;133:124-140.