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Volumn 16, Issue 8, 2011, Pages 7081-7096

Synthesis and electrophilic substitutions of novel pyrazolo[1,5-c]-1,2,4- triazolo[4,3-a]pyrimidines

Author keywords

Dehydrative cyclization; Electrophilic substitution reactions; Pyrazolo 1,5 c 1,2,4 triazolo 4,3 a pyrimidines; Synthesis

Indexed keywords

ACETIC ACID; ANTIFUNGAL AGENT; HALOGEN; PYRAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE; TRIAZOLE DERIVATIVE;

EID: 80052216062     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules16087081     Document Type: Article
Times cited : (5)

References (22)
  • 1
    • 0016428249 scopus 로고
    • Reactions with ß-cyanoethylhydrazine\-II: Synthesis of some 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine derivatives
    • Elnagdi, M.H.; Fleita, D.H.; Elmoghayar, M.R.H. Reactions with ß-cyanoethylhydrazine\-II: Synthesis of some 4,5,6,7-tetrahydropyrazolo[1, 5-a]pyrimidine derivatives. Tetrahedron 1975, 31, 63-67.
    • (1975) Tetrahedron , vol.31 , pp. 63-67
    • Elnagdi, M.H.1    Fleita, D.H.2    Elmoghayar, M.R.H.3
  • 2
    • 34247265250 scopus 로고
    • New Synthesis of Pyrazolo(1,5-c)pyrimidines from Acetylenic ß- Diketones
    • Marei, M.G.; Mishrikey, M.M.; Aly, D.M. New Synthesis of Pyrazolo(1,5-c)pyrimidines from Acetylenic ß- Diketones. Bull. Chem. Soc. Jpn. 1992, 65, 3419-3422.
    • (1992) Bull. Chem. Soc. Jpn. , vol.65 , pp. 3419-3422
    • Marei, M.G.1    Mishrikey, M.M.2    Aly, D.M.3
  • 3
    • 0023038196 scopus 로고
    • Investigation of pharmacological properties of some pyridinium salts, pyrazolines and pyrazoles
    • Zvezdina, E.A.; Zhdanova, M.P.I.; Nechayuk, I.I.; Barchan, A.; Simkina, Y.N.; Buchnaya, T.A. Investigation of pharmacological properties of some pyridinium salts, pyrazolines and pyrazoles. Khim. Farm. Zh. 1986, 20, 1328-1331. (Pubitemid 17207085)
    • (1986) Khimiko Farmatsevticheskii Zhurnal , vol.20 , Issue.11 , pp. 1328-1331
    • Zvezdina, E.A.1    Zhdanova, M.P.2    Nechayuk, I.I.3
  • 4
    • 51849182540 scopus 로고
    • Nickel(II) and copper(II) complexes of 5-aryl-2-phenyl-6H-pyrazolo-[1,5- c]pyrimidine-7-thiones
    • Marei, M.G.; Hassaan, A.M.A. Nickel(II) and copper(II) complexes of 5-aryl-2-phenyl-6H-pyrazolo-[1,5-c]pyrimidine-7-thiones. Transition Met. Chem. 1992, 17, 489-490.
    • (1992) Transition Met. Chem. , vol.17 , pp. 489-490
    • Marei, M.G.1    Hassaan, A.M.A.2
  • 5
    • 0014102097 scopus 로고
    • The antitumor activity of Cu(II)KTS, the copper(II) chelate of 3-ethoxy-2-oxobutyraldehyde bis(thiosemicarbazone)
    • Grim, J.A.; Petering, H.G. The Antitumor Activity of Cu(II)KTS, the Copper(II) chelate of 3-ethoxy-2-oxobutyraldehyde bis(thiosemicarbazone). Cancer Res. 1967, 27, 1278-1285.
    • (1967) Cancer Res. , vol.27 , pp. 1278-1285
    • Grim, J.A.1    Petering, H.G.2
  • 6
    • 0020374880 scopus 로고
    • 2-Acetylpyridine thiosemicarbazones. 4. Complexes with transition metals as antimalarial and antileukemic agents
    • DOI 10.1021/jm00352a036
    • Scovill, J.P.; Klayman, D.L.; Franchino, C.F. 2-Acetylpyridine thiosemicarbazones. 4. Complexes with transition metals as antimalarial and antileukemic agents. J. Med. Chem. 1982, 25, 1261-1264. (Pubitemid 13241923)
    • (1982) Journal of Medicinal Chemistry , vol.25 , Issue.10 , pp. 1261-1264
    • Scovill, J.P.1    Klayman, D.L.2    Franchino, C.F.3
  • 9
    • 80052188217 scopus 로고
    • U.S. Patent 3 19 November [Chem. Abstr. 1975 82, 73044v]
    • Coffen, D.L.; Fryer, R.I.; Triazolobenzodiazepines. U.S. Patent 3,849,434, 19 November 1974; [Chem. Abstr. 1975, 82, 73044v].
    • (1974) Triazolobenzodiazepines , vol.849 , pp. 434
    • Coffen, D.L.1    Fryer, R.I.2
  • 10
    • 80052230780 scopus 로고
    • Patent 75100096 [Chem. Abstr. 1976 84, 59588k]
    • Shiroki, M.; Tahara, T.; Araki, K. Jap. Patent 75100096, 1975; [Chem. Abstr. 1976, 84, 59588k].
    • (1975) Jap.
    • Shiroki, M.1    Tahara, T.2    Araki, K.3
  • 11
    • 0015550844 scopus 로고
    • Antibacterial effect of furacriline on Brucella
    • [Chem. Abstr. 1973, 78 93044]
    • Povelitsa, F.D.; Gural, A.G. Antibacterial effect of furacriline on Brucella. Antibiotiki 1973, 18, 71-74; [Chem. Abstr. 1973, 78, 93044].
    • (1973) Antibiotiki , vol.18 , pp. 71-74
    • Povelitsa, F.D.1    Gural, A.G.2
  • 12
    • 41449111442 scopus 로고    scopus 로고
    • Synthesis, antimicrobial and anti-inflammatory activities of some 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles and 1,2,4-triazolo[3,4-b][1,3,4] thiadiazines bearing trichlorophenyl moiety
    • DOI 10.1016/j.ejmech.2007.06.026, PII S0223523407002565
    • Karegoudar, P.; Prasad, D.J.; Ashok, M.; Mahalinga, M.; Poojary, B.; Holla, B.S. Synthesis, antimicrobial and anti-inflammatory activities of some 1,2,4-triazolo[3,4-b] [1,3,4]thiadiazoles and 1,2,4-triazolo[3,4-b][1,3,4] thiadiazines bearing trichlorophenyl moiety. Eur. J. Med. Chem. 2008, 43, 808-815. (Pubitemid 351454053)
    • (2008) European Journal of Medicinal Chemistry , vol.43 , Issue.4 , pp. 808-815
    • Karegoudar, P.1    Prasad, D.J.2    Ashok, M.3    Mahalinga, M.4    Poojary, B.5    Holla, B.S.6
  • 13
    • 0019214524 scopus 로고
    • 4-Amino-3-mercapto-4H-1,2,4-triazoles and propargyl aldehydes: A new route to 3-R-8-aryl-1,2,4-triazolo[3,4-b]1,3,4-thiadiazepines
    • Heindel, N.D.; Reid, J.R. 4-Amino-3-mercapto-4H -1,2,4-triazoles and propargyl aldehydes: A new route to 3-R-8-aryl-1,2,4-triazolo[3,4-b]-1,3,4- thiadiazepines. J. Heterocycl. Chem. 1980, 17, 1087-1088. (Pubitemid 11249395)
    • (1980) Journal of Heterocyclic Chemistry , vol.17 , Issue.5 , pp. 1087-1088
    • Heindel, N.D.1    Reid, J.R.2
  • 14
    • 0028300116 scopus 로고
    • Synthesis, structural characterization, crystallographic analysis and antibacterial properties of some nitrofuryl triazolo[3,4-b]-1,3,4-thiadiazines
    • DOI 10.1016/0223-5234(94)90100-7
    • Holla, B.S.; Kalluraya, B.; Sridhar, K.R.; Drake, E.; Thomas, L.M.; Bhandary, K.K.; Levine, M.S. Synthesis, structural characterization, crystallographic analysis and antibacterial properties of some nitrofuryl triazolo[3,4-b]-1,3,4-thiadiazine. Eur. J. Med. Chem. 1994, 29, 301-308. (Pubitemid 24148838)
    • (1994) European Journal of Medicinal Chemistry , vol.29 , Issue.4 , pp. 301-308
    • Holla, B.S.1    Kalluraya, B.2    Sridhar, K.R.3    Drake, E.4    Thomas, L.M.5    Bhandary, K.K.6    Levine, M.J.7
  • 15
    • 33748462990 scopus 로고    scopus 로고
    • Heterocyclic system containing bridgehead nitrogen atom: synthesis and pharmacological activities of some substituted 1,2,4-triazolo[3,4-b]-1,3,4- thiadiazoles
    • DOI 10.1016/j.ejmech.2006.03.018, PII S0223523406001358
    • Mathew, V.; Keshavayya, J.; Vidya, V.P.; Acharya; Reddy, B.M. Heterocyclic system containing bridgehead nitrogen atom: Synthesis and pharmacological activities of some substituted 1,2,4-triazolo[3,4-b]-1,3,4- thiadiazoles. Eur. J. Med. Chem. 2006, 41, 1048-1058. (Pubitemid 44353864)
    • (2006) European Journal of Medicinal Chemistry , vol.41 , Issue.9 , pp. 1048-1058
    • Mathew, V.1    Keshavayya, J.2    Vaidya, V.P.3
  • 17
    • 0034797998 scopus 로고    scopus 로고
    • Present status and perspectives on antimycoties with systematic effects
    • Haber, J. Present status and perspectives on antimycoties with systematic effects. Cas. Lek. Cesk. 2001, 140, 596.
    • (2001) Cas. Lek. Cesk. , vol.140 , pp. 596
    • Haber, J.1
  • 18
  • 19
    • 79952010615 scopus 로고    scopus 로고
    • Synthesis and reactions of a new series of 1,2,4-triazolo[4,3-c] quinazolines
    • Atta, K.F.M.; Marei, M.G.; Mohamed, F.A.M. Synthesis and reactions of a new series of 1,2,4-triazolo[4,3-c]quinazolines. Heterocycles 2011, 83, 339-349.
    • (2011) Heterocycles , vol.83 , pp. 339-349
    • Atta, K.F.M.1    Marei, M.G.2    Mohamed, F.A.M.3
  • 20
    • 79961157183 scopus 로고    scopus 로고
    • Annulation and evaluation of antibacterial activity of the new fused tricyclic(5,5,6)ring system of pyrazolo[1,5-c]-1,2,4-triazolo[4,3-a]pyrimidines
    • Atta, K.F.M.; Marei, M.G.; Abd El-Magiad, S.M.; El-Nashar, F.H.A. Annulation and evaluation of antibacterial activity of the new fused tricyclic(5,5,6)ring system of pyrazolo[1,5-c]-1,2,4-triazolo[4,3-a]pyrimidines. Heterocycles 2011, 83, 1873-1888.
    • (2011) Heterocycles , vol.83 , pp. 1873-1888
    • Atta, K.F.M.1    Marei, M.G.2    Abd El-Magiad, S.M.3    El-Nashar, F.H.A.4
  • 21
    • 80052240655 scopus 로고    scopus 로고
    • Synthesis of 4-(1-phenyl-1 H-pyrazol-3-yl)[1,2,4]triazolo[4,3-a] quinoxalines and their 4-halogenopyrazolyl analogs
    • in press
    • Atta, K.F.M.; El Ashry, E.S.H. Synthesis of 4-(1-phenyl-1 H-pyrazol-3-yl)[1,2,4]triazolo[4,3-a] quinoxalines and their 4-halogenopyrazolyl analogs. J. Heterocycl. Chem. 2011, in press.
    • (2011) J. Heterocycl. Chem.
    • Atta, K.F.M.1    El Ashry, E.S.H.2
  • 22
    • 79961156588 scopus 로고
    • Reaction of pyrazolo[1,5-c]pyrimidinethiones with hydrazine: Synthesis of novel substituted pyrazolo[1,5-c]pyrimidine and pyrazolo[1,5-c]tetrazolo[1,5-a] pyrimidine derivatives
    • Marei, M.G.; El-Ghanam, M. Reaction of pyrazolo[1,5-c]pyrimidinethiones with hydrazine: Synthesis of novel substituted pyrazolo[1,5-c]pyrimidine and pyrazolo[1,5-c]tetrazolo[1,5-a]pyrimidine derivatives. J. Chem. Res. 1993, 2175-2188.
    • (1993) J. Chem. Res. , pp. 2175-2188
    • Marei, M.G.1    El-Ghanam, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.