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Volumn 71, Issue 17, 2011, Pages 5881-5890

Chromogranin A restricts drug penetration and limits the ability of NGR-TNF to enhance chemotherapeutic efficacy

Author keywords

[No Author keywords available]

Indexed keywords

CHROMOGRANIN A; DOXORUBICIN; MELPHALAN; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCLONAL ANTIBODY; NGR TUMOR NECROSIS FACTOR; OMEPRAZOLE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN;

EID: 80052203877     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-11-1273     Document Type: Article
Times cited : (23)

References (50)
  • 1
    • 33746491709 scopus 로고    scopus 로고
    • Drug penetration in solid tumours
    • DOI 10.1038/nrc1893, PII NRC1893
    • Minchinton AI, Tannock IF. Drug penetration in solid tumours. Nat Rev Cancer 2006;6:583-92.(Pubitemid 44140857)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.8 , pp. 583-592
    • Minchinton, A.I.1    Tannock, I.F.2
  • 2
    • 0028470454 scopus 로고
    • Barriers to drug delivery in solid tumors
    • Jain RK. Barriers to drug delivery in solid tumors. Sci Am 1994;271:58-65.
    • (1994) Sci Am , vol.271 , pp. 58-65
    • Jain, R.K.1
  • 3
    • 0033764170 scopus 로고    scopus 로고
    • Enhancement of tumor necrosis factor alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13)
    • Curnis F, Sacchi A, Borgna L, Magni F, Gasparri A, Corti A. Enhancement of tumor necrosis factor alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13). Nat Biotechnol 2000;18:1185-90.
    • (2000) Nat Biotechnol , vol.18 , pp. 1185-1190
    • Curnis, F.1    Sacchi, A.2    Borgna, L.3    Magni, F.4    Gasparri, A.5    Corti, A.6
  • 4
    • 0036678474 scopus 로고    scopus 로고
    • Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration
    • DOI 10.1172/JCI200215223
    • Curnis F, Sacchi A, Corti A. Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration. J Clin Inv 2002;110:475-82.(Pubitemid 34919701)
    • (2002) Journal of Clinical Investigation , vol.110 , Issue.4 , pp. 475-482
    • Curnis, F.1    Sacchi, A.2    Corti, A.3
  • 5
    • 0036468937 scopus 로고    scopus 로고
    • Differential binding of drugs containing the NGR motif to CD13 isoforms in tumor vessels, epithelia, and myeloid cells
    • Curnis F, Arrigoni G, Sacchi A, Fischetti L, Arap W, Pasqualini R, et al. Differential binding of drugs containing the NGR motif to CD13 isoforms in tumor vessels, epithelia, and myeloid cells. Cancer Res 2002;62:867-74. (Pubitemid 34126966)
    • (2002) Cancer Research , vol.62 , Issue.3 , pp. 867-874
    • Curnis, F.1    Arrigoni, G.2    Sacchi, A.3    Fischetti, L.4    Arap, W.5    Pasqualini, R.6    Corti, A.7
  • 6
    • 0032535999 scopus 로고    scopus 로고
    • Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model
    • DOI 10.1126/science.279.5349.377
    • Arap W, Pasqualini R, Ruoslahti E. Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. Science 1998;279:377-80. (Pubitemid 28063372)
    • (1998) Science , vol.279 , Issue.5349 , pp. 377-380
    • Arap, W.1    Pasqualini, R.2    Ruoslahti, E.3
  • 8
    • 31544436380 scopus 로고    scopus 로고
    • Synergistic antitumor activity of cisplatin, paclitaxel, and gemcitabine with tumor vasculature-targeted tumor necrosis factor-alpha
    • DOI 10.1158/1078-0432.CCR-05-1147
    • Sacchi A, Gasparri A, Gallo-Stampino C, Toma S, Curnis F, Corti A. Synergistic antitumor activity of cisplatin, paclitaxel, and gemcitabine with tumor vasculature-targeted tumor necrosis factor-alpha. Clin Cancer Res 2006;12:175-82.(Pubitemid 43166192)
    • (2006) Clinical Cancer Research , vol.12 , Issue.1 , pp. 175-182
    • Sacchi, A.1    Gasparri, A.2    Gallo-Stampino, C.3    Toma, S.4    Curnis, F.5    Corti, A.6
  • 9
    • 67650638995 scopus 로고    scopus 로고
    • Phase Ib study of NGR-hTNF, a selective vascular targeting agent, administered at low doses in combination with doxorubicin to patients with advanced solid tumours
    • Gregorc V, Santoro A, Bennicelli E, Punt CJ, Citterio G, Timmer- Bonte JN, et al. Phase Ib study of NGR-hTNF, a selective vascular targeting agent, administered at low doses in combination with doxorubicin to patients with advanced solid tumours. Br J Cancer 2009;101:219-24.
    • (2009) Br J Cancer , vol.101 , pp. 219-224
    • Gregorc, V.1    Santoro, A.2    Bennicelli, E.3    Punt, C.J.4    Citterio, G.5    Timmer-Bonte, J.N.6
  • 10
    • 77956414169 scopus 로고    scopus 로고
    • Phase II study of asparagine-glycine-arginine-human tumor necrosis factor alpha, a selective vascular targeting agent, in previously treated patients with malignant pleural mesothelioma
    • Gregorc V, Zucali PA, Santoro A, Ceresoli GL, Citterio G, De Pas TM, et al. Phase II study of asparagine-glycine-arginine-human tumor necrosis factor alpha, a selective vascular targeting agent, in previously treated patients with malignant pleural mesothelioma. J Clin Oncol 2010;28:2604-11.
    • (2010) J Clin Oncol , vol.28 , pp. 2604-2611
    • Gregorc, V.1    Zucali, P.A.2    Santoro, A.3    Ceresoli, G.L.4    Citterio, G.5    De Pas, T.M.6
  • 11
    • 71049169690 scopus 로고    scopus 로고
    • Defining the optimal biological dose of NGR-hTNF, a selective vascular targeting agent, in advanced solid tumours
    • Gregorc V, Citterio G, Vitali G, Spreafico A, Scifo P, Borri A, et al. Defining the optimal biological dose of NGR-hTNF, a selective vascular targeting agent, in advanced solid tumours. Eur J Cancer 2010;46:198-206.
    • (2010) Eur J Cancer , vol.46 , pp. 198-206
    • Gregorc, V.1    Citterio, G.2    Vitali, G.3    Spreafico, A.4    Scifo, P.5    Borri, A.6
  • 12
    • 77956438555 scopus 로고    scopus 로고
    • Activity and safety of NGR-hTNF, a selective vascular-targeting agent, in previously treated patients with advanced hepatocellular carcinoma
    • Santoro A, Pressiani T, Citterio G, Rossoni G, Donadoni G, Pozzi F, et al. Activity and safety of NGR-hTNF, a selective vascular-targeting agent, in previously treated patients with advanced hepatocellular carcinoma. Br J Cancer 2010;103:837-44.
    • (2010) Br J Cancer , vol.103 , pp. 837-844
    • Santoro, A.1    Pressiani, T.2    Citterio, G.3    Rossoni, G.4    Donadoni, G.5    Pozzi, F.6
  • 13
    • 79953329168 scopus 로고    scopus 로고
    • Two doses of NGR-hTNF in combination with capecitabine plus oxaliplatin in colorectal cancer patients failing standard therapies
    • Mammoliti S, Andretta V, Bennicelli E, Caprioni F, Comandini D, Fornarini G, et al. Two doses of NGR-hTNF in combination with capecitabine plus oxaliplatin in colorectal cancer patients failing standard therapies. Ann Oncol 2011;22:973-8.
    • (2011) Ann Oncol , vol.22 , pp. 973-978
    • Mammoliti, S.1    Andretta, V.2    Bennicelli, E.3    Caprioni, F.4    Comandini, D.5    Fornarini, G.6
  • 14
    • 84864830965 scopus 로고    scopus 로고
    • Targeted drug delivery and penetration into solid tumors
    • Feb 1. doi: 10.1002/med.20238. [Epub ahead of print]
    • Corti A,Pastorino F,Curnis F, Arap W,Ponzoni M, Pasqualini R. Targeted drug delivery and penetration into solid tumors. Med Res Rev 2011 Feb 1. doi: 10.1002/med.20238. [Epub ahead of print].
    • (2011) Med Res Rev
    • Corti, A.1    Pastorino, F.2    Curnis, F.3    Arap, W.4    Ponzoni, M.5    Pasqualini, R.6
  • 15
    • 2442698028 scopus 로고    scopus 로고
    • Chromogranin A protects vessels against tumor necrosis factor alpha-induced vascular leakage
    • Ferrero E, Scabini S, Magni E, Foglieni C, Belloni D, Colombo B, et al. Chromogranin A protects vessels against tumor necrosis factor alpha-induced vascular leakage. FASEB J 2004;18:554-6.
    • (2004) FASEB J , vol.18 , pp. 554-556
    • Ferrero, E.1    Scabini, S.2    Magni, E.3    Foglieni, C.4    Belloni, D.5    Colombo, B.6
  • 16
    • 38549120838 scopus 로고    scopus 로고
    • The endocrine role for chromogranin A: A prohormone for peptides with regulatory properties
    • DOI 10.1007/s00018-007-7254-0
    • Helle KB, Corti A, Metz-Boutigue MH, Tota B. The endocrine role for chromogranin A: a prohormone for peptides with regulatory properties. Cell Mol Life Sci 2007;64:2863-86.(Pubitemid 351152248)
    • (2007) Cellular and Molecular Life Sciences , vol.64 , Issue.22 , pp. 2863-2886
    • Helle, K.B.1    Corti, A.2    Metz-Boutigue, M.-H.3    Tota, B.4
  • 18
    • 33744535874 scopus 로고    scopus 로고
    • The chromogranin A peptide vasostatin-I inhibits gap formation and signal transduction mediated by inflammatory agents in cultured bovine pulmonary and coronary arterial endothelial cells
    • DOI 10.1016/j.regpep.2006.04.007, PII S0167011506000589
    • Blois A, Srebro B, Mandalà M, Corti A, Helle KB, Serck-Hanssen G. The chromogranin A peptide vasostatin-I inhibits gap formation and signal transduction mediated by inflammatory agents in cultured bovine pulmonary and coronary arterial endothelial cells. Reg Pept 2006;135:78-84.(Pubitemid 43816103)
    • (2006) Regulatory Peptides , vol.135 , Issue.1-2 , pp. 78-84
    • Blois, A.1    Srebro, B.2    Mandala, M.3    Corti, A.4    Helle, K.B.5    Serck-Hanssen, G.6
  • 20
    • 0021211038 scopus 로고
    • Radioimmunoassay of chromogranin A in plasma as a measure of exocytotic sympathoadrenal activity in normal subjects and patients with pheochromocytoma
    • O'Connor DT, Bernstein KN. Radioimmunoassay of chromogranin A in plasma as a measure of exocytotic sympathoadrenal activity in normal subjects and patients with pheochromocytoma. New Engl J Med 1984;311:764-70.(Pubitemid 14026227)
    • (1984) New England Journal of Medicine , vol.311 , Issue.12 , pp. 764-770
    • O'Connor, D.T.1    Bernstein, K.N.2
  • 25
    • 60549095841 scopus 로고    scopus 로고
    • Serum concentration of chromogranin A at admission: An early biomarker of severity in critically ill patients
    • Zhang D, Lavaux T, Sapin R, Lavigne T, Castelain V, Aunis D, et al. Serum concentration of chromogranin A at admission: an early biomarker of severity in critically ill patients. Ann Med 2009;41:38-44.
    • (2009) Ann Med , vol.41 , pp. 38-44
    • Zhang, D.1    Lavaux, T.2    Sapin, R.3    Lavigne, T.4    Castelain, V.5    Aunis, D.6
  • 28
    • 0031043307 scopus 로고    scopus 로고
    • Basal chromogranin A and gastrin concentrations in circulation correlate to endocrine cell proliferation in type-A gastritis
    • Borch K, Stridsberg M, Burman P, Rehfeld JF. Basalchromogranin A and gastrin concentrations in circulation correlate to endocrine cell proliferation in type-A gastritis. Scand J Gastroenterol 1997;32:198-202.(Pubitemid 27105292)
    • (1997) Scandinavian Journal of Gastroenterology , vol.32 , Issue.3 , pp. 198-202
    • Borch, K.1    Stridsberg, M.2    Burman, P.3    Rehfeld, J.F.4
  • 29
    • 79151484434 scopus 로고    scopus 로고
    • Chromogranin A and the tumor microenvironment
    • Corti A. Chromogranin A and the tumor microenvironment. Cell Mol Neurobiol 2010;30:1163-70.
    • (2010) Cell Mol Neurobiol , vol.30 , pp. 1163-1170
    • Corti, A.1
  • 32
    • 1842422422 scopus 로고    scopus 로고
    • Effect of short-term treatment with low dosages ot the proton-pump inhibitor omeprazole on serum chromogranin A levels in man
    • DOI 10.1530/eje.0.1500299
    • Giusti M, Sidoti M, Augeri C, Rabitti C, Minuto F. Effect of short-term treatment with lowdosages of the proton-pumpinhibitoromeprazole on serum chromogranin A levels in man. Eur J Endocrinol 2004;150:299-303.(Pubitemid 38443779)
    • (2004) European Journal of Endocrinology , vol.150 , Issue.3 , pp. 299-303
    • Giusti, M.1    Sidoti, M.2    Augeri, C.3    Rabitti, C.4    Minuto, F.5
  • 35
    • 0030029125 scopus 로고    scopus 로고
    • Antigenic regions of human chromogranin A and their topographic relationships with structural/functional domains
    • Corti A, Longhi R, Gasparri A, Chen F, Pelagi M, Siccardi AG. Antigenic regions of human chromogranin A and their topographic relationships with structural/functional domains. Eur J Biochem 1996;235:275-80.(Pubitemid 26045443)
    • (1996) European Journal of Biochemistry , vol.235 , Issue.1-2 , pp. 275-280
    • Corti, A.1    Longhi, R.2    Gasparri, A.3    Chen, F.4    Pelagi, M.5    Siccardi, A.G.6
  • 36
    • 0034703077 scopus 로고    scopus 로고
    • Structure-activity relationships of chromogranin A in cell adhesion. Identification of an adhesion site for fibroblasts and smooth muscle cells
    • DOI 10.1074/jbc.M003796200
    • Ratti S, Curnis F, Longhi R, Colombo B, Gasparri A, Magni F, et al. Structure-activity relationships of chromogranin A in cell adhesion. Identification and characterization of an adhesion site for fibroblasts and smooth muscle cells. J Biol Chem 2000;275:29257-63.(Pubitemid 32043794)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.38 , pp. 29257-29263
    • Ratti, S.1    Curnis, F.2    Longhi, R.3    Colombo, B.4    Gasparri, A.5    Magni, F.6    Manera, E.7    Metz-Boutigue, M.-H.8    Corti, A.9
  • 38
    • 0024309730 scopus 로고
    • Tumor necrosis factor/cachectin increases permeability of endothelial cell monolayers by a mechanism involving regulatory G proteins
    • DOI 10.1084/jem.169.6.1977
    • Brett J, Gerlach H, Nawroth P, Steinberg S, Godman G, Stern D. Tumor necrosis factor/cachectin increases permeability of endothelial cell monolayers by a mechanism involving regulatory G proteins. J Exp Med 1989;169:1977-91. (Pubitemid 19162960)
    • (1989) Journal of Experimental Medicine , vol.169 , Issue.6 , pp. 1977-1991
    • Brett, J.1    Gerlach, H.2    Nawroth, P.3    Steinberg, S.4    Godman, G.5    Stern, D.6
  • 39
    • 0036635932 scopus 로고    scopus 로고
    • The role of p38 map kinase in tumor necrosis factor-induced redistribution of vascular endothelial cadherin and increased endothelial permeability
    • Nwariaku FE, Chang J, Zhu X, Liu Z, Duffy SL, Halaihel NH, et al. The role of p38 map kinase in tumor necrosis factor-induced redistribution of vascular endothelial cadherin and increased endothelial permeability. Shock 2002;18:82-5.
    • (2002) Shock , vol.18 , pp. 82-85
    • Nwariaku, F.E.1    Chang, J.2    Zhu, X.3    Liu, Z.4    Duffy, S.L.5    Halaihel, N.H.6
  • 41
    • 0034960085 scopus 로고    scopus 로고
    • Effect of long-term, continuous versus alternate-day omeprazole therapy on serum gastrin in patients treated for reflux esophagitis
    • DOI 10.1097/00004836-200107000-00008
    • Ligumsky M, Lysy J, Siguencia G, Friedlander Y. Effect of long-term, continuous versus alternate-day omeprazole therapy on serum gastrin in patients treated for reflux esophagitis. J Clin Gastroenterol 2001;33:32-5.(Pubitemid 32613575)
    • (2001) Journal of Clinical Gastroenterology , vol.33 , Issue.1 , pp. 32-35
    • Ligumsky, M.1    Lysy, J.2    Siguencia, G.3    Friedlander, Y.4
  • 42
    • 0033978486 scopus 로고    scopus 로고
    • Personal review: Is profound acid inhibition safe?
    • DOI 10.1046/j.1365-2036.2000.00681.x
    • Waldum HL, Brenna E. Personal review: is profound acid inhibition safe? Aliment Pharmacol Ther 2000;14:15-22.(Pubitemid 30058156)
    • (2000) Alimentary Pharmacology and Therapeutics , vol.14 , Issue.1 , pp. 15-22
    • Waldum, H.L.1    Brenna, E.2
  • 43
    • 78349311403 scopus 로고    scopus 로고
    • Effects of chromogranin A deficiency and excess in vivo:Biphasic blood pressure and catecholamine responses
    • Vaingankar SM, Li Y, Biswas N, Gayen J, Choksi S, Rao F, et al. Effects of chromogranin A deficiency and excess in vivo: biphasic blood pressure and catecholamine responses. J Hypertens 2010; 28:817-25.
    • (2010) J Hypertens , vol.28 , pp. 817-825
    • Vaingankar, S.M.1    Li, Y.2    Biswas, N.3    Gayen, J.4    Choksi, S.5    Rao, F.6
  • 44
    • 1542613798 scopus 로고    scopus 로고
    • Chromogranin A N-terminal fragments vasostatin-1 and the synthetic CGA 7-57 peptide act as cardiostatins on the isolated working frog heart
    • DOI 10.1016/j.ygcen.2003.12.012, PII S0016648003004519
    • Corti A, Mannarino C, Mazza R, Angelone T, Longhi R, Tota B. Chromogranin A N-terminal fragments vasostatin-1 and the synthetic CGA 7-57 peptide act as cardiostatins on the isolated working frog heart. Gen Comp Endocrinol 2004;136:217-24.(Pubitemid 38340784)
    • (2004) General and Comparative Endocrinology , vol.136 , Issue.2 , pp. 217-224
    • Corti, A.1    Mannarino, C.2    Mazza, R.3    Angelone, T.4    Longhi, R.5    Tota, B.6
  • 45
  • 47
    • 38749141779 scopus 로고    scopus 로고
    • A phase 2 study of carboplatin plus docetaxel in men with metastatic hormone-refractory prostate cancer who are refractory to docetaxel
    • DOI 10.1002/cncr.23195
    • Ross RW, Beer TM, Jacobus S, Bubley GJ, Taplin ME, Ryan CW, et al. A phase 2 study of carboplatin plus docetaxel in men with metastatic hormone-refractory prostate cancer who are refractory to docetaxel. Cancer 2008;112:521-6.(Pubitemid 351186193)
    • (2008) Cancer , vol.112 , Issue.3 , pp. 521-526
    • Ross, R.W.1    Beer, T.M.2    Jacobus, S.3    Bubley, G.J.4    Taplin, M.-E.5    Ryan, C.W.6    Huang, J.7    Oh, W.K.8
  • 49
    • 33644606173 scopus 로고    scopus 로고
    • Circulating chromogranin A and hormone refractory prostate cancer chemotherapy
    • Cabrespine A, Guy L, Gachon F, Cure H, Chollet P, Bay JO. Circulating chromogranin A and hormone refractory prostate cancer chemotherapy. J Urol 2006;175:1347-52.
    • (2006) J Urol , vol.175 , pp. 1347-1352
    • Cabrespine, A.1    Guy, L.2    Gachon, F.3    Cure, H.4    Chollet, P.5    Bay, J.O.6
  • 50
    • 78650993549 scopus 로고    scopus 로고
    • Firstline chemotherapy with capecitabine and temozolomide in patients with metastaticpancreatic endocrinecarcinomas
    • Strosberg JR, Fine RL, Choi J, Nasir A, Coppola D, Chen DT, et al. Firstline chemotherapy with capecitabine and temozolomide in patients with metastaticpancreatic endocrinecarcinomas.Cancer2011;117:268-75.
    • (2011) Cancer , vol.117 , pp. 268-275
    • Strosberg, J.R.1    Fine, R.L.2    Choi, J.3    Nasir, A.4    Coppola, D.5    Chen, D.T.6


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