Age as a modulator of inflammatory cardiovascular risk factors

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 31, Issue 9, 2011, Pages 2151-2156

  Anuurad, Erdembileg ^a   Enkhmaa, Byambaa ^a   Gungor, Zeynep ^a,c   Zhang, Wei ^a   Tracy, Russell P ^d   Pearson, Thomas A ^e   Kim, Kyoungmi ^b   Berglund, Lars ^a,f  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c ISTANBUL UNIVERSITY   (Turkey)

^d UNIVERSITY OF VERMONT   (United States)

^e UNIVERSITY OF ROCHESTER   (United States)

^f Northern California Health Care System   (United States)

Author keywords

aging; coronary artery disease; epidemiology; risk factors

Indexed keywords

C REACTIVE PROTEIN; FIBRINOGEN; PENTRAXIN 3; PHOSPHOLIPASE A2; SERUM AMYLOID A;

ADULT; AGING; ARTICLE; CARDIOVASCULAR INFLAMMATION; CARDIOVASCULAR RISK; DISEASE MARKER; ETHNIC DIFFERENCE; ETHNICITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RISK FACTOR;

AFRICAN AMERICANS; AGE FACTORS; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CARDIOVASCULAR DISEASES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; FIBRINOGEN; HUMANS; INFLAMMATION; MALE; MIDDLE AGED; PHOSPHOLIPASES A2; RISK FACTORS; SERUM AMYLOID A PROTEIN; SERUM AMYLOID P-COMPONENT;

EID: 80052175092     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.111.232348     Document Type: Article

References (34)

1. Ross R. Atherosclerosis: an inflammatory disease. N Engl J Med. 1999; 340:115-126.
2. Ridker PM, Rifai N, Rose L, Buring JE, Cook NR. Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N Engl J Med. 2002;347: 1557-1565. (Pubitemid 35315836)
3. Ridker PM, Buring JE, Shih J, Matias M, Hennekens CH. Prospective study of C-reactive protein and the risk of future cardiovascular events among apparently healthy women. Circulation. 1998;98:731-733. (Pubitemid 28391836)
4. Kannel WB, Wolf PA, Castelli WP, D'Agostino RB. Fibrinogen and risk of cardiovascular disease: the Framingham Study. JAMA. 1987;258: 1183-1186.
5. Cantin B, Despres JP, Lamarche B, Moorjani S, Lupien PJ, Bogaty P, Bergeron J, Dagenais GR. Association of fibrinogen and lipoprotein(a) as a coronary heart disease risk factor in men (the Quebec Cardiovascular Study). Am J Cardiol. 2002;89:662-666. (Pubitemid 34230560)
6. Caslake MJ, Packard CJ. Lipoprotein-associated phospholipase A2 (platelet-activating factor acetylhydrolase) and cardiovascular disease. Curr Opin Lipidol. 2003;14:347-352. (Pubitemid 36951899)
7. Packard CJ, O'Reilly DS, Caslake MJ, McMahon AD, Ford I, Cooney J, Macphee CH, Suckling KE, Krishna M, Wilkinson FE, Rumley A, Lowe GD. Lipoprotein-associated phospholipase A2 as an independent predictor of coronary heart disease: West of Scotland Coronary Prevention Study Group. N Engl J Med. 2000;343:1148-1155.
8. Lavi S, McConnell JP, Rihal CS, Prasad A, Mathew V, Lerman LO, Lerman A. Local production of lipoprotein-associated phospholipase A2 and lysophosphatidylcholine in the coronary circulation: association with early coronary atherosclerosis and endothelial dysfunction in humans. Circulation. 2007;115:2715-2721. (Pubitemid 46842787)
9. Santos S, Rooke TW, Bailey KR, McConnell JP, Kullo IJ. Relation of markers of inflammation (C-reactive protein, white blood cell count, and lipoprotein-associated phospholipase A2) to the ankle-brachial index. Vasc Med. 2004;9:171-176. (Pubitemid 40124080)
10. Miller MA, Cappuccio FP. Ethnicity and inflammatory pathways: implications for vascular disease, vascular risk and therapeutic intervention. Curr Med Chem. 2007;14:1409-1425. (Pubitemid 46902223)
11. Beckett N, Nunes M, Bulpitt C. Is it advantageous to lower cholesterol in the elderly hypertensive? Cardiovasc Drugs Ther. 2000;14:397-405. (Pubitemid 30663721)
12. Ahluwalia N, Mastro AM, Ball R, Miles MP, Rajendra R, Handte G. Cytokine production by stimulated mononuclear cells did not change with aging in apparently healthy, well-nourished women. Mech Ageing Dev. 2001;122:1269-1279. (Pubitemid 32579201)
13. Ballou SP, Lozanski FB, Hodder S, Rzewnicki DL, Mion LC, Sipe JD, Ford AB, Kushner I. Quantitative and qualitative alterations of acute-phase proteins in healthy elderly persons. Age Ageing. 1996;25: 224-230. (Pubitemid 26152041)
14. Wei J, Xu H, Davies JL, Hemmings GP. Increase of plasma IL-6 concentration with age in healthy subjects. Life Sci. 1992;51:1953-1956.
15. Enkhmaa B, Anuurad E, Ozturk Z, Zhang W, Pearson T, Berglund L. Differential associations of serum amyloid A and pentraxin-3 with allelespecific lipoprotein(a) levels in African Americans and Caucasians. Transl Res. 2011;in press.
16. Paultre F, Pearson TA, Weil HF, Tuck CH, Myerson M, Rubin J, Francis CK, Marx HF, Philbin EF, Reed RG, Berglund L. High levels of Lp(a) with a small apo(a) isoform are associated with coronary artery disease in African American and white men. Arterioscler Thromb Vasc Biol. 2000; 20:2619-2624.
17. Anuurad E, Rubin J, Lu G, Pearson TA, Holleran S, Ramakrishnan R, Berglund L. Protective effect of apolipoprotein E2 on coronary artery disease in African Americans is mediated through lipoprotein cholesterol. J Lipid Res. 2006;47:2475-2481. (Pubitemid 44936109)
18. McGowan MW, Artiss JD, Strandbergh DR, Zak B. A peroxidasecoupled method for the colorimetric determination of serum triglycerides. Clin Chem. 1983;29:538-542. (Pubitemid 13160770)
19. Allain CC, Poon LS, Chan CS, Richmond W, Fu PC. Enzymatic determination of total serum cholesterol. Clin Chem. 1974;20:470-475.
20. Warnick GR, Benderson J, Albers JJ. Dextran sulfate-Mg2 precipitation procedure for quantitation of high-density-lipoprotein cholesterol. Clin Chem. 1982;28:1379-1388. (Pubitemid 12125081)
21. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972;18:499-502.
22. Macy EM, Hayes TE, Tracy RP. Variability in the measurement of C-reactive protein in healthy subjects: implications for reference intervals and epidemiological applications. Clin Chem. 1997;43:52-58. (Pubitemid 27024390)
23. Ridker PM, Cushman M, Stampfer MJ, Tracy RP, Hennekens CH. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med. 1997;336:973-979. (Pubitemid 27152782)
24. Clauss A. [Rapid physiological coagulation method in determination of fibrinogen.] Acta Haematol. 1957;17:237-246.
25. Adler AI, Levy JC, Matthews DR, Stratton IM, Hines G, Holman RR. Insulin sensitivity at diagnosis of Type 2 diabetes is not associated with subsequent cardiovascular disease (UKPDS 67). Diabet Med. 2005;22: 306-311. (Pubitemid 40313858)
26. Dada N, Kim NW, Wolfert RL. Lp-PLA2: an emerging biomarker of coronary heart disease. Expert Rev Mol Diagn. 2002;2:17-22. (Pubitemid 34654407)
27. Koenig W, Twardella D, Brenner H, Rothenbacher D. Lipoproteinassociated phospholipase A2 predicts future cardiovascular events in patients with coronary heart disease independently of traditional risk factors, markers of inflammation, renal function, and hemodynamic stress. Arterioscler Thromb Vasc Biol. 2006;26:1586-1593. (Pubitemid 44288987)
28. Kosaka T, Yamaguchi M, Soda Y, Kishimoto T, Tago A, Toyosato M, Mizuno K. Spectrophotometric assay for serum platelet-activating factor acetylhydrolase activity. Clin Chim Acta. 2000;296:151-161. (Pubitemid 30243147)
29. National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation. 2002;106:3143-3421.
30. Tracy RP, Lemaitre RN, Psaty BM, Ives DG, Evans RW, Cushman M, Meilahn EN, Kuller LH. Relationship of C-reactive protein to risk of cardiovascular disease in the elderly. Results from the Cardiovascular Health Study and the Rural Health Promotion Project. Arterioscler Thromb Vasc Biol. 1997;17:1121-1127.
31. Ferrucci L, Corsi A, Lauretani F, Bandinelli S, Bartali B, Taub DD, Guralnik JM, Longo DL. The origins of age-related proinflammatory state. Blood. 2005;105:2294-2299. (Pubitemid 40387022)
32. Anuurad E, Ozturk Z, Enkhmaa B, Pearson TA, Berglund L. Association of lipoprotein-associated phospholipase A2 with coronary artery disease in African-Americans and Caucasians. J Clin Endocrinol Metab. 2010; 95:2376-2383.
33. Anuurad E, Tracy RP, Pearson TA, Kim K, Berglund L. Synergistic role of inflammation and insulin resistance as coronary artery disease risk factors in African Americans and Caucasians. Atherosclerosis. 2009;205: 290-295.
34. Anuurad E, Tracy RP, Pearson TA, Beckett L, Berglund L. Comparison of C-reactive protein and metabolic syndrome as cardiovascular risk factors in African-Americans and European-Americans. Am J Cardiol. 2009;103:523-527.