Liver attenuation, pericardial adipose tissue, obesity, and insulin resistance: The multi-ethnic study of atherosclerosis (MESA)

Obesity

Volumn 19, Issue 9, 2011, Pages 1855-1860

  McAuley, Paul A ^a   Hsu, Fang Chi ^b   Loman, Kurt K ^b   Carr, J Jeffrey ^b   Budoff, Matthew J ^c   Szklo, Moyses ^d   Sharrett, A Richey ^d   Ding, Jingzhong ^b  

^a WINSTON SALEM STATE UNIVERSITY   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

^c LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE   (United States)

^d JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABDOMINAL OBESITY; ADIPOSE TISSUE; ADULT; ARTICLE; ATHEROSCLEROSIS; BODY MASS; CARDIOVASCULAR DISEASE; CAUCASIAN; CHINESE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; ETHNICITY; FEMALE; HISPANIC; HUMAN; INSULIN RESISTANCE; LIVER ATTENUATION; MAJOR CLINICAL STUDY; MALE; NEGRO; NONALCOHOLIC FATTY LIVER; PERICARDIAL ADIPOSE TISSUE; PERICARDIUM; SEX DIFFERENCE; WAIST CIRCUMFERENCE;

ADIPOSE TISSUE, WHITE; ADIPOSITY; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; BODY MASS INDEX; COHORT STUDIES; CROSS-SECTIONAL STUDIES; FATTY LIVER; FEMALE; HUMANS; INSULIN RESISTANCE; LIVER; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; OBESITY; OBESITY, ABDOMINAL; PERICARDIUM; PREVALENCE; SEX CHARACTERISTICS; UNITED STATES; WAIST CIRCUMFERENCE;

EID: 80052152898     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2011.191     Document Type: Article

References (30)

1. Kim SH, Abbasi F, Reaven GM. Impact of degree of obesity on surrogate estimates of insulin resistance. Diabetes Care 2004;27:1998-2002. (Pubitemid 38989245)
2. Karter AJ, Mayer-Davis EJ, Selby JV et al. Insulin sensitivity and abdominal obesity in African-American, Hispanic, and non-Hispanic white men and women. The Insulin Resistance and Atherosclerosis Study. Diabetes 1996;45:1547-1555. (Pubitemid 26357548)
3. Garg A. Lipodystrophies. Am J Med 2000;108:143-152. (Pubitemid 30064425)
4. Carr A, Cooper DA. Adverse effects of antiretroviral therapy. Lancet 2000;356:1423-1430.
5. Klein S, Fontana L, Young VL et al. Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease. N Engl J Med 2004;350:2549-2557. (Pubitemid 38758542)
6. Angulo P. Obesity and nonalcoholic fatty liver disease. Nutr Rev 2007;65:S57-S63.
7. Browning JD, Szczepaniak LS, Dobbins R et al. Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology 2004;40:1387-1395. (Pubitemid 39657013)
8. Ding J, Kritchevsky SB, Hsu FC et al. Association between nonsubcutaneous adiposity and calcified coronary plaque: a substudy of the Multi-Ethnic Study of Atherosclerosis. Am J Clin Nutr 2008;88:645-650.
9. Singh N, Singh H, Khanijoun HK, Iacobellis G. Echocardiographic assessment of epicardial adipose tissue-a marker of visceral adiposity. Mcgill J Med 2007;10:26-30. (Pubitemid 46535696)
10. Iacobellis G, Leonetti F. Epicardial adipose tissue and insulin resistance in obese subjects. J Clin Endocrinol Metab 2005;90:6300-6302. (Pubitemid 41606560)
11. Bild DE, Bluemke DA, Burke GL et al. Multi-ethnic study of atherosclerosis: objectives and design. Am J Epidemiol 2002;156:871-881. (Pubitemid 35215769)
12. Matthews DR, Hosker JP, Rudenski AS et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28:412-419. (Pubitemid 15018832)
13. Sacks HS, Fain JN. Human epicardial adipose tissue: a review. Am Heart J 2007;153:907-917. (Pubitemid 46809849)
14. Fain JN, Sacks HS, Bahouth SW et al. Human epicardial adipokine messenger RNAs: comparisons of their expression in substernal, subcutaneous, and omental fat. Metab Clin Exp 2010;59:1379-1386.
15. Wheeler GL, Shi R, Beck SR et al. Pericardial and visceral adipose tissues measured volumetrically with computed tomography are highly associated in type 2 diabetic families. Invest Radiol 2005;40:97-101. (Pubitemid 40144415)
16. Bydder GM, Chapman RW, Harry D et al. Computed tomography attenuation values in fatty liver. J Comput Tomogr 1981;5:33-35. (Pubitemid 11075771)
17. Guerrero R, Vega GL, Grundy SM, Browning JD. Ethnic differences in hepatic steatosis: an insulin resistance paradox? Hepatology 2009;49:791-801.
18. MacKay MF, Haffner SM, Wagenknecht LE, D'Agostino RB Jr, Hanley AJ. Prediction of type 2 diabetes using alternate anthropometric measures in a multi-ethnic cohort: the insulin resistance atherosclerosis study. Diabetes Care 2009;32:956-958.
19. Calle EE, Thun MJ, Petrelli JM, Rodriguez C, Heath CW Jr. Body-mass index and mortality in a prospective cohort of U.S. adults. N Engl J Med 1999;341:1097-1105. (Pubitemid 29466221)
20. Vanni E, Bugianesi E, Kotronen A et al. From the metabolic syndrome to NAFLD or vice versa? Dig Liver Dis 2010;42:320-330.
21. Kissebah AH, Krakower GR. Regional adiposity and morbidity. Physiol Rev 1994;74:761-811. (Pubitemid 24328939)
22. Malaguarnera M, Di Rosa M, Nicoletti F, Malaguarnera L. Molecular mechanisms involved in NAFLD progression. J Mol Med 2009;87:679-695.
23. Samuel VT, Liu ZX, Wang A et al. Inhibition of protein kinase Cepsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease. J Clin Invest 2007;117:739-745. (Pubitemid 46348532)
24. Hotamisligil GS. Inflammation and endoplasmic reticulum stress in obesity and diabetes. Int J Obes (Lond) 2008;32 Suppl 7:S52-S54.
25. Targher G, Bellis A, Fornengo P et al. Prevention and treatment of nonalcoholic fatty liver disease. Dig Liver Dis 2010;42:331-340.
26. Johnson NA, Sachinwalla T, Walton DW et al. Aerobic exercise training reduces hepatic and visceral lipids in obese individuals without weight loss. Hepatology 2009;50:1105-1112.
27. Church TS, Kuk JL, Ross R et al. Association of cardiorespiratory fitness, body mass index, and waist circumference to nonalcoholic fatty liver disease. Gastroenterology 2006;130:2023-2030. (Pubitemid 43816951)
28. Iacobellis G, Singh N, Wharton S, Sharma AM. Substantial changes in epicardial fat thickness after weight loss in severely obese subjects. Obesity (Silver Spring) 2008;16:1693-1697. (Pubitemid 351915121)
29. Bosy-Westphal A, Kossel E, Goele K et al. Association of pericardial fat with liver fat and insulin sensitivity after diet-induced weight loss in overweight women. Obesity (Silver Spring) 2010;18:2111-2117.
30. Katsuki A, Sumida Y, Gabazza EC et al. Homeostasis model assessment is a reliable indicator of insulin resistance during follow-up of patients with type 2 diabetes. Diabetes Care 2001;24: 362-365. (Pubitemid 32119139)