Dynamic enhancement of the rat inner ear after ultra-small-volume administration of gd-dota to the medial wall of the middle ear cavity

ORL

Volumn 73, Issue 5, 2011, Pages 275-281

  Zou, Jing ^a,c   Yoshida, Tadao ^a   Ramadan, Usama A ^b   Pyykkö, Ilmari ^a  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Contrast agent; Drug delivery; Inner ear; Magnetic resonance imaging; Targeting

Indexed keywords

GADOTERIC ACID; POLYIMIDE;

ANIMAL EXPERIMENT; ARTICLE; COCHLEA; CONTRAST ENHANCEMENT; DRUG DISTRIBUTION; DRUG UPTAKE; IN VIVO STUDY; INNER EAR; MALE; MIDDLE EAR; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT; SCALA TYMPANI; SCALA VESTIBULI; SIGNAL NOISE RATIO; VESTIBULE;

ANIMALS; CONTRAST MEDIA; DISEASE MODELS, ANIMAL; EAR DISEASES; EAR, INNER; EAR, MIDDLE; GADOLINIUM; HETEROCYCLIC COMPOUNDS; INJECTIONS; MAGNETIC RESONANCE IMAGING; MALE; ORGANOMETALLIC COMPOUNDS; RATS; RATS, WISTAR; REPRODUCIBILITY OF RESULTS;

EID: 80052077447     PISSN: 03011569     EISSN: 14230275     Source Type: Journal    
DOI: 10.1159/000329760     Document Type: Article

References (17)

1. Counter SA, Bjelke B, Borg E, et al: Magnetic resonance imaging of the membranous labyrinth during in vivo gadolinium (Gd-DTPA-BMA) uptake in the normal and lesioned cochlea. Neuroreport 2000;11:3979-3983. (Pubitemid 32038788)
2. Zou J, Pyykko I, Bretlau P, et al: In vivo visualization of endolymphatic hydrops in guinea pigs: magnetic resonance imaging evaluation at 4.7 Tesla. Ann Otol Rhinol Laryngol 2003;112:1059-1065. (Pubitemid 37523621)
3. Zou J, Zhang W, Poe D, et al: Differential passage of gadolinium through the mouse inner ear barriers evaluated with 4.7 T MRI. Hear Res 2009;259:36-43.
4. Zou J, Poe D, Bjelke B, et al: Visualization of inner ear disorders with MRI in vivo: from animal models to human application. Acta Otolaryngol Suppl 2009;560:22-31.
5. Pyykko I, Zou J, Poe D, et al: Magnetic resonance imaging of the inner ear in Meniere's disease. Otolaryngol Clin North Am 2010;43:1059-1080.
6. Zou J, Pyyk ko I, Bjel ke B, et al: Communication between the perilymphatic scalae and spiral ligament visualized by in vivo MRI. Audiol Neurootol 2005;10:145-152. (Pubitemid 40663392)
7. Naganawa S, Sugiura M, Kawamura M, et al: Imaging of endolymphatic and perilymphatic fluid at 3T after intratympanic administration of gadolinium-diethylene-triamine pentaacetic acid. AJNR Am J Neuroradiol 2008;29:724-726. (Pubitemid 351571554)
8. Nakashima T, Naganawa S, Sugiura M, et al: Visualization of endolymphatic hydrops in patients with Meniere's disease. Laryngoscope 2007;117:415-420. (Pubitemid 46407747)
9. Duan M, Bjelke B, Fridberger A, et al: Imaging of the guinea pig cochlea following round window gadolinium application. Neuroreport 2004;15:1927-1930. (Pubitemid 39180615)
10. Zou J, Li M, Zhang Y, et al: Transport augmentation through the blood-inner ear barriers of guinea pigs treated with 3-nitropropionic acid and patients with acute hearing loss, visualized with 3.0 T MRI. Otol Neurotol 2011;32:204-212.
11. Zou J, Ramadan UA, Pyykko I: Gadolinium uptake in the rat inner ear perilymph evaluated with 4.7 T MRI: a comparison between transtympanic injection and gelatin spongebased diffusion through the round window membrane. Otol Neurotol 2010;31:637-641.
12. Liu F, Huang W, Wang Z, et al: Noninvasive evaluation of endoly mphatic space in healthy volunteers using magnetic resonance imaging. Acta Otolaryngol 2011;13:247-257.
13. Johnson DG, Zhu XX, Frisina RD, et al: Micro-molded cannulae for intracochlear infusions in small rodents. Conf Proc IEEE Eng Med Biol Soc 2007;2007:6617-6620.
14. Zink WE, Foley CP, Dyke JP, et al: Novel microcatheters for selective intra-arterial injection of fluid in the rat brain. AJNR Am J Neuroradiol 2009;30:1190-1196.
15. Zou J, Sood R, Ranjan S, et al: Manufacturing and in vivo inner ear visualization of MRI traceable liposome nanoparticles encapsulating gadolinium. J Nanobiotechnology 2010;8:32.
16. Ohashi M, Ide S, Sawaguchi A, et al: Histochemical localization of the extracellular matrix components in the annular ligament of rat stapediovestibular joint with special reference to fibrillin, 36-kDa microfibril-associated glycoprotein (MAGP-36), and hyaluronic acid. Med Mol Morphol 2008;41:28-33. (Pubitemid 351677141)
17. Saijo S, Kimura RS: Distribution of HRP in the inner ear after injection into the middle ear cavity. Acta Otolaryngol 1984;97:593-610. (Pubitemid 14122226)