Optimization of therapeutic proteins to delete T-cell epitopes while maintaining beneficial residue interactions.

Journal of bioinformatics and computational biology

Volumn 9, Issue 2, 2011, Pages 207-229

  Parker, Andrew S ^a   Griswold, Karl E ^b   Bailey Kellogg, Chris ^b  

^a Dartmouth Department of Computer Science_Dartmouth College

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AUR PROTEIN, STAPHYLOCOCCUS AUREUS; BLOOD CLOTTING FACTOR 8; EPITOPE; HLA DR ANTIGEN; METALLOPROTEINASE; PEPTIDE FRAGMENT; RECOMBINANT ERYTHROPOIETIN; RECOMBINANT PROTEIN;

ALGORITHM; ALLELE; ANIMAL; ARTICLE; BIOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER PROGRAM; COMPUTER SIMULATION; DRUG DESIGN; GENE DELETION; GENETICS; HUMAN; IMMUNOLOGY; MUTAGENESIS; PROTEIN ENGINEERING; STATISTICS;

ALGORITHMS; ALLELES; ANIMALS; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; DRUG DESIGN; EPITOPES, T-LYMPHOCYTE; ERYTHROPOIETIN, RECOMBINANT; FACTOR VIII; HLA-DR ANTIGENS; HUMANS; METALLOENDOPEPTIDASES; MODELS, MOLECULAR; MUTAGENESIS; PEPTIDE FRAGMENTS; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; SEQUENCE DELETION; SOFTWARE;

EID: 80052071931     PISSN: 02197200     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0219720011005471     Document Type: Article

References (0)