All PUFAs are not created equal: Absence of CHD benefit specific to linoleic acid in randomized controlled trials and prospective observational cohorts

World Review of Nutrition and Dietetics

Volumn 102, Issue , 2011, Pages 30-43

  Ramsden, Christopher E ^a   Hibbeln, Joseph R ^a   Majchrzak Hong, Sharon F ^a  

^a Laboratory of Membrane Biochemistry and Biophysics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LINOLEIC ACID; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID;

ARTICLE; CALORIC INTAKE; CORONARY ARTERY DISEASE; DIET; EVIDENCE BASED MEDICINE; FAT INTAKE; HUMAN; META ANALYSIS (TOPIC); PRACTICE GUIDELINE; RANDOMIZED CONTROLLED TRIAL (TOPIC); RISK FACTOR;

CORONARY DISEASE; DIET; DIETARY FATS; ENERGY INTAKE; EVIDENCE-BASED MEDICINE; FATTY ACIDS, OMEGA-3; FATTY ACIDS, OMEGA-6; GUIDELINES AS TOPIC; HUMANS; LINOLEIC ACID; META-ANALYSIS AS TOPIC; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RISK FACTORS;

EID: 80052065191     PISSN: 00842230     EISSN: 16623975     Source Type: Book Series    
DOI: 10.1159/000327789     Document Type: Article

References (43)

1. Mozaffarian D, Micha R, Wallace S: Effects on coronary heart disease of increasing polyunsaturated fat in place of saturated fat: a systematic review and meta-analysis of randomized controlled trials. Plos Med 2010;7:1-10.
2. Mensink R P, et al: Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials. Am J Clin Nutr 2003;77:1146-1155.
3. Jakobsen MU, et al: Major types of dietary fat and risk of coronary heart disease: a pooled analysis of 11 cohort studies. Am J Clin Nutr 2009;89:1425-1432.
4. Katan MB: Omega-6 polyunsaturated fatty acids and coronary heart disease. Am J Clin Nutr 2009;89:1283-1284.
5. Harris WS, et al: Omega-6 fatty acids and risk for cardiovascular disease: a science advisory from the American Heart Association Nutrition Subcommittee of the Council on Nutrition, Physical Activity, and Metabolism; Council on Cardiovascular Nursing; and Council on Epidemiology and Prevention. Circulation 2009;119:902-907.
6. Kris-Etherton P, Fleming J, Harris WS: The debate about n-6 polyunsaturated fatty acid recommendations for cardiovascular health. J Am Diet Assoc, 2010;110:201-204.
7. Kris-Etherton P, Harris WS: Dietary omega-6 polyunsaturated fatty acidsimportant for heart health. Clin Nutr Insight 2009;35:1-5.
8. Harris WS: Response to Letter to Editor re: Linoleic acid and coronary heart disease. Prostaglandins Leukot Essent Fatty Acids 2008;80:78-79.
9. Gordon D: Lowering cholesterol and total mortality; in Rifkin BM (ed): Lowering Cholesterol in High Risk Individuals and Populations. New York, Marcel Dekker, 1995, pp 33-48.
10. Leren P: The effect of plasma cholesterol lowering diet in male survivors of myocardial infarction. A controlled clinical trial. Acta Med Scand Suppl 1966;466:1-92.
11. Medical Research Council: Controlled trial of soya-bean oil in myocardial infarction. Lancet 1968;ii:693-699.
12. Hiscock E, et al: A palatable diet high in unsaturated fat. J Am Diet Assoc 1962;40:427-431.
13. Watts GF, et al: Dietary fatty acids and progression of coronary artery disease in men. Am J Clin Nutr 1996;64:202-209.
14. Low-fat diet in myocardial infarction: a controlled trial. Lancet 1965;ii:501-504.
15. Ramsden C: A misrepresented metaanalysis (letter). Circulation 2009; CIRCULATIONAHA/2009/865667.
16. Ramsden, C. E., Hibbeln, J., Lands, B., Tribole, E. 'Omega-6 fatty acids and risk for cardiovascular disease', 865667, 866566, 866434, 868448. Circulation 2009; letters to the editor.
17. WHO: Diet, Nutrition and the Prevention of Chronic Diseases: Report of a Joint WHO/FAO expert consultation, report 916, Geneva, WHO, 2003.
18. Burr ML, et al: Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: diet and reinfarction trial (DART). Lancet 1989;ii:757-761.
19. US Department of Health and Human Services and US Department of Agriculture. Dietary Guidelines for Americans, 2005, ed 6. 2005.
20. Frantz ID Jr, et al: Test of effect of lipid lowering by diet on cardiovascular risk. The Minnesota Coronary Survey. Arteriosclerosis 1989;9:129-135.
21. Frantz ID Jr, Keys A: R01 HE 0986-03 research grant application: effect of a dietary change on human cardiovascular disease 'The Minnesota Coronary Survey', 1967.
22. Rose GA, Thomson WB, Williams RT: Corn oil in treatment of ischaemic heart disease. Br Med J 1965;i:1531-1533.
23. Woodhill JM, et al: Low fat, low cholesterol diet in secondary prevention of coronary heart disease. Adv Exp Med Biol, 1978;109:317-330.
24. Ramsden CE, et al: n-6 fatty acid-specific and mixed polyunsaturate dietary interventions have different effects on CHD risk: a meta-analysis of randomised controlled trials. Br J Nutr 2010;104:1586-1600.
25. Hu FB, et al: Dietary fat intake and the risk of coronary heart disease in women. N Engl J Med 1997;337:1491-1499.
26. Hu FB, et al: Dietary intake of alphalinolenic acid and risk of fatal ischemic heart disease among women. Am J Clin Nutr 1999;69:890-897.
27. Ascherio A, et al: Dietary fat and risk of coronary heart disease in men: cohort follow-up study in the United States. BMJ 1996;313:84-90.
28. Mozaffarian D, et al: Interplay between different polyunsaturated fatty acids and risk of coronary heart disease in men. Circulation 2005;111:157-164.
29. Garland M, et al: The relation between dietary intake and adipose tissue composition of selected fatty acids in US women. Am J Clin Nutr 1998;67:25-30.
30. Hodson L, Skeaff CM, Fielding BA: Fatty acid composition of adipose tissue and blood in humans and its use as a biomarker of dietary intake. Prog Lipid Res 2008;47:348-380.
31. Hunter DJ, et al: Comparison of measures of fatty acid intake by subcutaneous fat aspirate, food frequency questionnaire, and diet records in a free-living population of US men. Am J Epidemiol 1992;135:418-427.
32. USDA (2007-2008) Away from Home: Percentages of Selected Nutrients Contributed by Foods Away from Home, by Gender and Age, NHANES. What We Eat in America.
33. Oh K, et al: Dietary fat intake and risk of coronary heart disease in women: 20 years of follow-up of the nurses' health study. Am J Epidemiol 2005;161:672-679.
34. Simpson SH, et al: A meta-analysis of the association between adherence to drug therapy and mortality. BMJ 2006;333:15.
35. Ovbiagele B, et al: Relationship between non-specific prescription pill adherence and ischemic stroke outcomes. Cerebrovasc Dis 2010;29:146-153.
36. Curtis JR, et al: The relationship between bisphosphonate adherence and fracture: is it the behavior or the medication? Results from the placebo arm of the fracture intervention trial. J Bone Miner Res 2010.
37. Page IH, Allen EA, Chamberlain FL, et al: Dietary fat and its relation to heart attacks and strokes. Circulation, 1961;23:133-136.
38. Grodstein F, et al: Postmenopausal estrogen and progestin use and the risk of cardiovascular disease. N Engl J Med, 1996;335:453-461.
39. Stampfer MJ, Colditz GA: Estrogen replacement therapy and coronary heart disease: a quantitative assessment of the epidemiologic evidence. Prev Med 1991;20:47-63.
40. Nelson HD, et al: Postmenopausal hormone replacement therapy: scientific review. JAMA 2002;288:872-881.
41. Grodstein F: Invited commentary: can selection bias explain the cardiovascular benefits of estrogen replacement therapy? Am J Epidemiol 1996;143:979-982; discussion 983-984.
42. Goldbourt U, Yaari S, Medalie JH: Factors predictive of long-term coronary heart disease mortality among 10, 059 male Israeli civil servants and municipal employees. A 23-year mortality followup in the Israeli Ischemic Heart Disease Study. Cardiology, 1993;82:100-121.
43. Jakobsen MU, et al: Dietary fat and risk of coronary heart disease: possible effect modification by gender and age. Am J Epidemiol, 2004;160:141-149.