Mcl-1 ubiquitination and destruction

Oncotarget

Volumn 2, Issue 3, 2011, Pages 239-244

  Inuzuka, Hiroyuki ^a   Fukushima, Hidefumi ^a   Shaik, Shavali ^a   Liu, Pengda ^a   Lau, Alan W ^a   Wei, Wenyi ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Apoptosis; Cell cycle; Fbw7; GSK3; Mcl 1; Phosphorylation; SCF; Tumor suppressor; Ubiquitination

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; F BOX PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN FBW7; PROTEIN KINASE B; PROTEIN MCL 1; SORAFENIB; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; FBXW7 PROTEIN, HUMAN; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; PROTEIN BCL 2; UBIQUITIN PROTEIN LIGASE;

ACUTE LYMPHOBLASTIC LEUKEMIA; APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CONCENTRATION RESPONSE; DOWN REGULATION; DRUG EFFECT; HUMAN; MOLECULAR DYNAMICS; MOLECULARLY TARGETED THERAPY; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; T CELL LEUKEMIA; UBIQUITINATION; UPREGULATION; DRUG ANTAGONISM; GENETICS; METABOLISM; REVIEW; TUMOR CELL LINE;

CELL CYCLE PROTEINS; CELL LINE, TUMOR; F-BOX PROTEINS; HUMANS; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTO-ONCOGENE PROTEINS C-BCL-2; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 80052056009     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.242     Document Type: Article

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