Structure-guided activity restoration of the silkworm glutathione transferase Omega GSTO3-3

Journal of Molecular Biology

Volumn 412, Issue 2, 2011, Pages 204-211

  Chen, Bao Yu ^a   Ma, Xiao Xiao ^a   Guo, Peng Chao ^a   Tan, Xiang ^b   Li, Wei Fang ^a   Yang, Jie Pin ^a   Zhang, Nan Nan ^a   Chen, Yuxing ^a   Xia, Qingyou ^b   Zhou, Cong Zhao ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b SOUTHWEST UNIVERSITY   (China)

Author keywords

Bombyx mori; crystal structure; enzymatic activity; glutathione transferase Omega; site directed mutagenesis

Indexed keywords

ASPARAGINE; CYSTEINE; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE OMEGA 3; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME STRUCTURE; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; SILKWORM;

BOMBYX MORI;

EID: 80052036835     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2011.07.019     Document Type: Article

References (36)

1. Hayes J.D., Flanagan J.U., and Jowsey I.R. Glutathione transferases Annu. Rev. Pharmacol. Toxicol. 45 2005 51 88 (Pubitemid 40261798)
2. Sheehan D., Meade G., Foley V.M., and Dowd C.A. Structure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamily Biochem. J. 360 2001 1 16 (Pubitemid 33081943)
3. Armstrong R.N. Structure, catalytic mechanism, and evolution of the glutathione transferases Chem. Res. Toxicol. 10 1997 2 18 (Pubitemid 27044902)
4. Yu S.J. Detection and biochemical characterization of insecticide resistance in fall armyworm (Lepidoptera: Noctuidae) J. Econ. Entomol. 85 1992 675 682
5. Hayes J.D., and Pulford D.J. The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance Crit. Rev. Biochem. Mol. Biol. 30 1995 445 600
6. Allocati N., Federici L., Masulli M., and Di Ilio C. Glutathione transferases in bacteria FEBS J. 276 2009 58 75
7. Ma X.X., Jiang Y.L., He Y.X., Bao R., Chen Y., and Zhou C.Z. Structures of yeast glutathione-S-transferase Gtt2 reveal a new catalytic type of GST family EMBO Rep. 10 2009 1320 1326
8. Casalone E., Allocati N., Ceccarelli I., Masulli M., Rossjohn J., Parker M.W., and Di Ilio C. Site-directed mutagenesis of the Proteus mirabilis glutathione transferase B1-1 G-site FEBS Lett. 423 1998 122 124 (Pubitemid 28343193)
9. Yu S.J. Insect glutathione S-transferases Zool. Stud. 35 1996 9 19 (Pubitemid 126062901)
10. Zhou Z.H., and Syvanen M. A complex glutathione transferase gene family in the housefly Musca domestica Mol. Gen. Genet. 256 1997 187 194
11. Yu Q., Lu C., Li B., Fang S., Zuo W., and Dai F. Identification, genomic organization and expression pattern of glutathione S-transferase in the silkworm, Bombyx mori Insect Biochem. Mol. Biol. 38 2008 1158 1164
12. Ding Y., Ortelli F., Rossiter L.C., Hemingway J., and Ranson H. The Anopheles gambiae glutathione transferase supergene family: annotation, phylogeny and expression profiles BMC Genomics 4 2003 35
13. Board P.G., Coggan M., Chelvanayagam G., Easteal S., Jermiin L.S., and Schulte G.K. Identification, characterization, and crystal structure of the Omega class glutathione transferases J. Biol. Chem. 275 2000 24798 24806 (Pubitemid 30626584)
14. Rossjohn J., Polekhina G., Feil S.C., Allocati N., Masulli M., De Illio C., and Parker M.W. A mixed disulfide bond in bacterial glutathione transferase: functional and evolutionary implications Structure 6 1998 721 734 (Pubitemid 28301206)
15. Zhang Z.R., Bai M., Wang X.Y., Zhou J.M., and Perrett S. "Restoration" of glutathione transferase activity by single-site mutation of the yeast prion protein Ure2 J. Mol. Biol. 384 2008 641 651
16. Rhee J.S., Lee Y.M., Hwang D.S., Lee K.W., Kim I.C., and Shin K.H. Molecular cloning and characterization of omega class glutathione S-transferase (GST-O) from the polychaete Neanthes succinea: biochemical comparison with theta class glutathione S-transferase (GST-T) Comp. Biochem. Physiol., Toxicol. Pharmacol. 146 2007 471 477
17. Allocati N., Federici L., Masulli M., Favaloro B., and Di Ilio C. Cysteine 10 is critical for the activity of Ochrobactrum anthropi glutathione transferase and its mutation to alanine causes the preferential binding of glutathione to the H-site Proteins 71 2008 16 23 (Pubitemid 351358587)
18. Vararattanavech A., and Ketterman A.J. A functionally conserved basic residue in glutathione transferases interacts with the glycine moiety of glutathione and is pivotal for enzyme catalysis Biochem. J. 406 2007 247 256 (Pubitemid 47310955)
19. Nathaniel C., Wallace L.A., Burke J., and Dirr H.W. The role of an evolutionarily conserved cis-proline in the thioredoxin-like domain of human class Alpha glutathione transferase A1-1 Biochem. J. 372 2003 241 246 (Pubitemid 36609627)
20. Hegazy U.M., Mannervik B., and Stenberg G. Functional role of the lock and key motif at the subunit interface of glutathione transferase P1-1 J. Biol. Chem. 279 2004 9586 9596 (Pubitemid 38296027)
21. Whitbread A.K., Tetlow N., Eyre H.J., Sutherland G.R., and Board P.G. Characterization of the human Omega class glutathione transferase genes and associated polymorphisms Pharmacogenetics 13 2003 131 144 (Pubitemid 36324243)
22. Jones D.T. Protein secondary structure prediction based on position-specific scoring matrices J. Mol. Biol. 292 1999 195 202 (Pubitemid 29435759)
23. Ishigaki S., Abramovitz M., and Listowsky I. Glutathione-S-transferases are major cytosolic thyroid hormone binding proteins Arch. Biochem. Biophys. 273 1989 265 272 (Pubitemid 19221980)
24. Tipping E., Ketterer B., and Koskelo P. The binding of porphyrins by ligandin Biochem. J. 169 1978 509 516 (Pubitemid 8281756)
25. Otwinowski Z., and Minor W. Processing of X-ray diffraction data collected in oscillation mode Macromol. Crystallogr., Part A, 1997 276 1997 307 326 (Pubitemid 27085611)
26. McCoy A.J. Solving structures of protein complexes by molecular replacement with Phaser Acta Crystallogr., Sect. D: Biol. Crystallogr. 63 2007 32 41
27. Bailey S. The CCP4 suite: programs for protein crystallography Acta Crystallogr., Sect. D: Biol. Crystallogr. 50 1994 760 763
28. Murshudov G.N., Vagin A.A., and Dodson E.J. Refinement of macromolecular structures by the maximum-likelihood method Acta Crystallogr., Sect. D: Biol. Crystallogr. 53 1997 240 255 (Pubitemid 27235885)
29. Emsley P., and Cowtan K. Coot: model-building tools for molecular graphics Acta Crystallogr., Sect. D: Biol. Crystallogr. 60 2004 2126 2132 (Pubitemid 41742764)
30. β deviation Proteins 50 2003 437 450
31. DeLano W. The PyMOL Molecular Graphics System 2002 DeLano Scientific San Carlos, CA
32. Habig W.H., and Jakoby W.B. Assays for differentiation of glutathione S-transferases Methods Enzymol. 77 1981 398 405
33. Kim J., Suh H., Kim S., Kim K., Ahn C., and Yim J. Identification and characteristics of the structural gene for the Drosophila eye colour mutant sepia, encoding PDA synthase, a member of the Omega class glutathione S-transferases Biochem. J. 398 2006 451 460 (Pubitemid 44453389)
34. Board P.G., and Anders M.W. Glutathione transferase omega 1 catalyzes the reduction of S-(phenacyl)glutathiones to acetophenones Chem. Res. Toxicol. 20 2007 149 154 (Pubitemid 46220165)
35. Yang J.T., Wu C.S., and Martinez H.M. Calculation of protein conformation from circular dichroism Methods Enzymol. 130 1986 208 269
36. 264 with diiodofluorescein iodacetamide as a tool to study the membrane topology of cytochrome P450scc (CYP11A1) FEBS Lett. 340 1994 83-88