Sesquiterpene lactones from Gynoxys verrucosa and their anti-MRSA activity

Journal of Ethnopharmacology

Volumn 137, Issue 2, 2011, Pages 1055-1059

  Ordóñez, Paola E ^a,c,e   Quave, Cassandra L ^b   Reynolds, William F ^d   Varughese, Kottayil I ^a,b   Berry, Brian ^e   Breen, Philip J ^a   Malagón, Omar ^c   Smeltzer, Mark S ^b   Compadre, Cesar M ^a,c  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c UNIVERSIDAD TÉCNICA PARTICULAR DE LOJA   (Ecuador)

^d UNIVERSITY OF TORONTO   (Canada)

^e University of Arkansas   (United States)

Author keywords

Dehydroleucodine; Gynoxys verrucosa; Leucodine; MRSA; Staphylococcus aureus; Staphylococcus epidermidis

Indexed keywords

ANTIINFECTIVE AGENT; ARNICOLIDE C; DEHYDROLEUCODINE; GYNOXYS VERRUCOSA EXTRACT; LEUCODINE; PLANT EXTRACT; SESQUITERPENE KETOLACTONE; SESQUITERPENE LACTONE DERIVATIVE; UNCLASSIFIED DRUG; XANTHATIN;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; CARBON NUCLEAR MAGNETIC RESONANCE; CRYSTAL STRUCTURE; DRUG ISOLATION; DRUG STRUCTURE; GYNOXYS VERRUCOSA; IN VITRO STUDY; MEDICINAL PLANT; MICROTITER PLATE ASSAY; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; SPECTROSCOPY; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; X RAY ANALYSIS;

ANTI-BACTERIAL AGENTS; ASTERACEAE; CRYSTALLOGRAPHY, X-RAY; INHIBITORY CONCENTRATION 50; LACTONES; MAGNETIC RESONANCE SPECTROSCOPY; METHICILLIN RESISTANCE; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PLANT COMPONENTS, AERIAL; SESQUITERPENES; STAPHYLOCOCCUS AUREUS;

ASTERACEAE; GYNOXYS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; VERRUCOSA;

EID: 80052036398     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.07.012     Document Type: Article

References (19)

1. D. Amsterdam Susceptibility testing of antimicrobials in liquid media V. Loman, Antibiotics in Laboratory Medicine 4th ed. 1996 Williams and Wilkins Baltimore, MD 52 111
2. R.H. Deurenberg, and E.E. Stobberingh The molecular evolution of hospital and community associated methicillin-resistant Staphylococcus aureus Current Molecular Medicine 9 2009 100 115
3. S. Gibbons Anti-staphylococcal plant natural products Natural Product Reports 21 2004 263 277 (Pubitemid 38527319)
4. F. Hilmi, O. Sticher, and J. Heilmann New cytotoxic sesquiterpene lactones from Warionia saharae Planta Medica 69 2003 462 464 (Pubitemid 36774190)
5. H.D. Isenberg Clinical Microbiology Procedures Handbook vol. 2 2004 5.1-5.1.15
6. R.M. Klevens, M.A. Morrison, J. Nadle, S. Petit, K. Gershman, S. Ray, L.H. Harrison, R. Lynfield, G. Dumyati, J.M. Townes, A.S. Craig, E.R. Zell, G.F. Fosheim, L.K. McDougal, R.B. Carey, and S.K. Fridkin Invasive methicillin-resistant Staphylococcus aureus infections in the United States Journal American Medical Association 298 2007 1763 1771 (Pubitemid 47598444)
7. C. Lee Therapeutic challenges in the era of antibiotic resistance International Journal of Antimicrobial Agents 54 2008 5197 5199
8. K.H. Lee, T. Ibuka, R.Y. Wu, and T.A. Geissman Structure-antimicrobial activity relationships among the sesquiterpene lactones and related compounds Phytochemsitry 16 1977 1177 1181
9. M. Martínez, and A. Muñoz-Zamora Conformational analysis of achillin and leukodin Journal of Natural Products 51 1988 221 228
10. K. Michalska, E. Szneler, and W. Kisie Sesquiterpenoids of Picris koreana and their chemotaxonomic significance Biochemical Systematics and Ecology 35 2007 459 461 (Pubitemid 46654591)
11. G. Rucker, E.P. Schenkel, D. Manns, R. Mayer, B.M. Hausen, and K. Heiden Allergenic sesquiterpene lactones From Eupatorium cannabinum L. and Kaunia rufescens (Lund ex de Candolle) Journal of Natural Toxins 5 1997 223 227 (Pubitemid 28257011)
12. T.J. Schmidt Toxic activities of sesquiterpene lactones: structural and biochemical aspects Current Organic Chemistry 3 1999 577 608 (Pubitemid 29515503)
13. C.D. Sifri, J. Park, G.A. Helm, M.E. Stemper, and S.K. Shukla Fatal brain abscess due to community-associated methicillin-resistant Staphylococcus aureus strain USA300 Clinical Infectious Disease 45 2007 113 117
14. M. Simoes, R.N. Bennettb, and E.A.S. Rosab Understanding antimicrobial activities of phytochemicals against multidrug resistant bacteria and biofilms Natural Product Reports 26 2009 746 757
15. V. Tene, O. Malagón, Vita, P. Finzi, G. Vidari, C. Armijos, and T. Zaragoza An ethnobotanical survey of medicinal plants used in Loja and Zamora-Chinchipe, Ecuador Journal of Ethnopharmacology 111 2007 63 81 (Pubitemid 46482884)
16. A. Trendafilova, M. Todorova, B. Mikhova, A. Vitkova, and H. Duddeck Sesquiterpene lactones from Achillea collina J. Becker ex Reichenb Phytochemistry 67 2006 764 770
17. A.E. Vega, G.H. Wendel, A.O.M. Maria, and L. Pelzer Antimicrobial activity of Artemisia douglasiana and dehydroleucodine against Helicobacter pylori Journal of Ethnopharmacology 124 2009 653 655
18. G.H. Wendel, A.O.M. María, J.A. Guzman, O. Giordano, and L.E. Pelzer Antidiarrheal activity of dehydroleucodine isolated from Artemisia douglasiana Fitoterapia 79 2008 1 5 (Pubitemid 350216281)
19. W. Zhu, N.C. Clark, L.K. McDougal, J. Hageman, L.C. McDonald, and J.B. Patel Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan Antimicrobial Agents and Chemotherapy 52 2008 452 457 (Pubitemid 351170813)