Association of the cannabinoid receptor 2 (CB2) Gln63Arg polymorphism with indices of liver damage in obese children: An alternative way to highlight the CB2 hepatoprotective properties

Hepatology

Volumn 54, Issue 3, 2011, Pages 1102-

  Rossi, Francesca ^a   Bellini, Giulia ^b   Nobili, Bruno ^a   Maione, Sabatino ^b   Perrone, Laura ^a   Giudice, Emanuele Miraglia del ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1 DEOXY 3 (1,1 DIMETHYLBUTYL) DELTA8 TETRAHYDROCANNABINOL; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CANNABINOID 2 RECEPTOR;

ACUTE HEPATITIS; ALLELE; BODY MASS; DISEASE ASSOCIATION; INSULIN RESISTANCE; INTRACELLULAR SIGNALING; LETTER; LIPID DIET; LIVER CIRRHOSIS; LIVER INJURY; LIVER PROTECTION; NONALCOHOLIC FATTY LIVER; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; WAIST HIP RATIO;

ANIMALS; DRUG-INDUCED LIVER INJURY; LIVER REGENERATION; PARACRINE COMMUNICATION; RECEPTOR, CANNABINOID, CB2;

EID: 80052035302     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.24440     Document Type: Letter

References (4)

1. Teixeira-Clerc F, Belot MP, Manin S, Deveaux V, Cadoudal T, Chobert MN, et al. Beneficial paracrine effects of cannabinoid receptor 2 on liver injury and regeneration. HEPATOLOGY 2010; 52: 1046-1059.
2. Deveaux V, Cadoudal T, Ichigotani Y, Teixeira-Clerc F, Louvet A, Manin S, et al. Cannabinoid CB2 receptor potentiates obesity-associated inflammation, insulin resistance and hepatic steatosis. PLoS One 2009; 4: e5844.
3. Feldstein AE, Charatcharoenwitthaya P, Treeprasertsuk S, Benson JT, Enders FB, Angulo P. The natural history of non-alcoholic fatty liver disease in children: a follow-up study for up to 20 years. Gut 2009; 58: 1538-1544.
4. Carrasquer A, Nebane NM, Williams WM, Song ZH. Functional consequences of nonsynonymous single nucleotide polymorphisms in the CB2 cannabinoid receptor. Pharmacogenet Genomics 2010; 20: 157-166.