Current status and development of hematopoietic stem cell transplantation in china: A report from chinese hematopoietic stem cell transplantation register group

Chinese Medical Journal

Volumn 124, Issue 16, 2011, Pages 2548-2555

  Xu, Lan Ping ^a   Huang, Xiao Jun ^a  

^a PEKING UNIVERSITY   (China)

Author keywords

Haploidentical; Hematopoietic stem cell transplantation; Registration; Unrelated

Indexed keywords

BASILIXIMAB; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; CYTARABINE; FLUDARABINE; GRANULOCYTE COLONY STIMULATING FACTOR; METHOTREXATE; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; THYMOCYTE ANTIBODY;

ACUTE GRAFT VERSUS HOST DISEASE; ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; APLASTIC ANEMIA; ARTICLE; BLOOD BANK; BONE MARROW CELL; CANCER COMBINATION CHEMOTHERAPY; CHINA; CHRONIC GRAFT VERSUS HOST DISEASE; CHRONIC MYELOID LEUKEMIA; CORD BLOOD STEM CELL TRANSPLANTATION; DISEASE CLASSIFICATION; DONOR LYMPHOCYTE INFUSION; DONOR SELECTION; DRUG SAFETY; DRUG TOLERABILITY; GEOGRAPHIC DISTRIBUTION; GRAFT VERSUS HOST REACTION; HIGH RISK PATIENT; HUMAN; LOW DRUG DOSE; MYELODYSPLASTIC SYNDROME; PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; PRACTICE GUIDELINE; PROGNOSIS; RECURRENT DISEASE; RISK ASSESSMENT; TREATMENT INDICATION; UNSPECIFIED SIDE EFFECT; VOLUNTEER;

CHINA; GEOGRAPHY; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; UNRELATED DONORS;

EID: 80052012983     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2011.16.027     Document Type: Article

References (38)

1. Huang XJ. HLA-mismatched/haploidentical hematopoietic stem cell transplantation: a field in which Chinese doctors are making great contributions. Chin Med J 2010; 123: 1235-1240.
2. Huang XJ, Liu DH, Liu KY, Xu LP, Chen H, Han W, et al. Haploidentical hematopoietic stem cell transplantation without in vitro T-cell depletion for the treatment of hematological malignancies. Bone Marrow Transplant 2006; 38: 291-297.
3. Xu LP, Liu KY, Liu DH, Chen H, Han W, Chen YH, et al. The inferiority of G-PB to rhG-CSF-mobilized blood and marrow grafts as a stem cell source in patients with high-risk acute leukemia who underwent unmanipulated HLA-mismatched/haploidentical transplantation: a comparative analysis. Bone Marrow Transplant 2010; 45: 985-992.
4. Yuan HL, Wen BZ, Qu JH, Li L, Jiang M, Hao JP, et al. Haploidentical peripheral blood stem cell transplantation without in vitro T-cell depletion for the treatment of malignant hematological diseases. J Clin Rehabilitative Tissue Engineering Res 2009; 13: 1185-1190.
5. Guo M, Sun Z, Sun QY, Han Q, Yu CL, Wang DH, et al. A modified haploidentical nonmyeloablative transplantation without T cell depletion for high-risk acute leukemia: successful engraftment and mild GVHD. Biol Blood Marrow Transplant 2009; 15: 930-937.
6. Wang HX, Ji SQ, Chen HR, Yan HM, Liu J, Zhu L, et al. Clinical study on hematooietic reconstitution in patients with leukemia by haploidentical bone marrow transplantation. J Exp Hematol 2003; 11: 426-419.
7. Yan HM, Xue M, Wang ZD, Zhu L, Liu J, Ding L, et al. Haploidentical allogeneic bone marrow stem cell transplantation combined with peripheral blood stem cells for therapy of leukemia. J Exp Hematol 2009; 17: 1330-1334.
8. Wang FR, Zhang YC, Lu DP. Successful transplantation of double unit cord blood from unrelated donors in high risk leukemia. Chin J Organ Transplant (Chin) 2003; 24: 217-219.
9. Ma X, Wu DP, Sun AN, Qiu HY, Fu ZZ, Tang XW, et al. A clinical study on double cord blood transplantation for adults patients with hematological diseases. Suzhou Univ J Med Sci (Chin) 2009; 29: 1177-1178.
10. Chinese Marrow Donor Program statistical information. (Accessed August 31, 2010 at http://www.cmdp.com.cn/ index.html)
11. Chen H. A report on clinical analysis of 721 unrelated donor hematopoietic stem cell transplantation cases. The Symposium on Development of HLA Mismatched HSCT 2010. Beijing, China, 2010.
12. Liang B, Huang H, Cai Z, Xie WZ, Li L, He JS, et al. A comparison of clinical outcomes between HLA allele matched and 1-2 alleles mismatched unrelated allogeneic bone marrow transplantations. Chin J Hematol (Chin) 2004; 25: 74-77.
13. Qu H, Sun J, Liu QF, Meng FY, Xu D, Zhang Y, et al. The impact of HLA incompatibility between unrelated donor and recipient on outcomes. J Chin Pract Intern Med (Chin) 2008; 24: 4076-4078.
14. Liu QF, Liu C, Zhang Y, Sun J, Yi ZS, Fan ZP, et al. Peripheral blood stem cell transplantation compared with bone marrow transplantation from unrelated donors in patients with leukemia: a single institutional experience. Blood Cells Mol Dis 2010; 45: 75-81.
15. Yang K, Liu QF, Fan ZP, Sun J, Xu D, Wei YQ, et al. A comparison of the therapeutic effects between related donor and unrelated donor allogeneic hematopoietic stem cell transplantation in treatment of leukemia. Chin J Intern Med 2007; 46: 135-139.
16. Song AX, Yang DL, Wei JL, Yan ZS, Wang M, Jiang EL, et al. Allogeneic stem cell transplantation for 75 cases of acute myeloid leukemia in complete remission: outcome and prognostic analysis. Chin J Exp Hematol (Chin) 2010; 18: 161-166.
17. Huang XJ, Liu DH, Liu KY, Xu LP, Chen H, Han W, et al. Treatment of acute leukemia with unmanipulated HLA-mismatched/haploidentical blood and bone marrow transplantation. Biol Blood Marrow Transplant 2009; 15: 257-265.
18. Chen Y, Liu K, Xu L, Chen H, Liu D, Zhang X, et al. HLA-mismatched hematopoietic SCT without in vitro T-cell depletion for myelodysplastic syndrome. Bone Marrow Transplant 2010; 45: 1333-1339.
19. National Comprehensive Cancer Network clinical practice guidelines in oncology: chronic myelogenous leukemia version 2. (Accessed June 20, 2011 at http://www.nccn.org/TM&Clinical Resources/)
20. Liu QF, Xu XJ, Chen YK, Sun J, Zhang Y, Fan ZP, et al. Long-term outcomes of HLA-matched sibling compared with mismatched related and unrelated donor hematopoietic stem cell transplantation for chronic phase chronic myelogenous leukemia: a single institution experience in China. Ann Hematol 2010; 90: 331-341.
21. Huang XJ, Xu LP, Liu KY, Liu DH, Chen H, Liu YR, et al. Individulized intervention guided by BCR-ABL transcript levels after HLA-identical sibling donor transplantation improves HSCT outcomes for patients with chronic myelod leukemia. Biol Blood Marrow Transplant 2010; Epub ahead of print.
22. Liang Y, Lai Y, Schwarzenberger P, Li Q, Ma J, Luo J, et al. Targeted agents for chronic myelogenous leukemia: will that be the end of allogeneic bone marrow transplantation for that disease? Biol Blood Marrow Transplantation 2011; 17: 649-656.
23. Huang XJ, Xu LP, Liu KY, Liu DH, Chen H, Chen YH et al. HLA-mismatched/haploidentical hematopoietic stem cell transplantation without in vitro T cell depletion for chronic myeloid leukemia: Improved outcomes in patients in accelerated phase and blast crisis phase. Ann Med 2008; 40: 444-455.
24. Jiang Q, Xu LP, Liu DH, Liu KY, Chen SS, Jiang B, et al. Imatinib mesylate versus allogeneic hematopoietic stem cell transplantation for patients with chronic myelogenous leukemia in accelerated phase. Blood 2011; 117: 3032-3040.
25. Jiang H, Huang XJ. Clinical practice guideline for chronic myelogenous leukemia and its practice in China. Chin J Pract Intern Med (Chin) 2010; 30: 32-34.
26. Liu QF, Sun J, Xu D, Zhang Y, Fan ZP, Wei YQ, et al. Effects of allogeneic hematopoietic stem cell transplantation with very-high-dose conditioning regimen for refractory leukemia, J First Milit Med Univ (Chin) 2004; 24: 1117-1119.
27. Ai HS, Huang XJ, Qiao ZH, Wang JM, Chen BA, Bai H, et al. Muticenter report of nonmyeloablative allogeneic stem cell transplantation for hematologic diseases. Chin J Hematol (Chin) 2009; 30: 505-508.
28. Lai Y, Ma J, Schwarzenberger P, Li W, Cai Z, Zhou J, et al. Combination of CsA, MTX and low-dose, short-course mycophenolate mofetil for GVHD prophylaxis. Bone Marrow Transplant 2009; 43: 61-67.
29. Li XH, Gao CJ, Da WM, Yu L, Wu XX, Li HH, et al. Prophylactic effect of CsA, MTX, MMF combined with ATG on GVHD in patients underwent unrelated PBSCT. Chin J Exp Hematol (Chin) 2010; 18: 458-462.
30. Ji SQ, Chen HR, Yan HM, Wang HX, Liu J, Zhu PY, et al. Anti-CD25 monoclonal antibody (basiliximab) for prevention of GVHD after haploidentical BMT for hematological malignancies. Bone Marrow Transplant 2005; 36: 349-54.
31. Huang XJ, Jiang Q, Chen H, Xu LP, Liu DH, Chen YH, et al. Methotrexate for treatment of graft versus host disease after allogeneic hematopoietic stem cell transplantation. Natl Med J China (Chin) 2005; 85: 1097-1101.
32. Wang Y, Xu LP, Liu KY, Liu DH, Wang J, Chen H, et al. Low-dose MTX combined with low-dose methylprednisolone as a first-line therapy for the treatment of acute GVHD: safety and feasibility. Bone Marrow Transplant 2010; 46: 892-898.
33. Huang XJ, Liu DH, Liu KY, Xu LP, Chen YH, Wang Y, et al. Modified donor lymphocyte infusion after HLA-mismatched/ haploidentical T cell-replete hematopoietic stem cell transplantation for prophylaxis of relapse of leukemia in patients with advanced leukemia. J Clin Immunol 2008; 28: 276-283.
34. Huang XJ, Wang Y, Liu DH, Xu LP, Chen H, Chen YH, et al. Modified donor lymphocyte infusion (DLI) for the prophylaxis of leukemia relapse after hematopoietic stem cell transplantation in patients with advanced leukemia: feasibility and safety study. J Clin Immunol 2008; 28: 390-397.
35. Lu DP, Dong L, Wu T, Huang XJ, Zhang MJ, Han W, et al. Conditioning including antithymocyte globulin followed by un-manipulated HLA-mismatched/haploidentical blood and marrow transplantation can achieve comparable outcomes to HLA-identical sibling transplantation. Blood 2006; 107: 3065-3073.
36. Wang Y, Liu DH, Xu LP, Liu KY, Chen H, Chen YH, et al. Superior graft-versus-leukemia effect associated with transplantation of haplo-identical compared with HLA-identical sibling donor grafts for high risk acute leukemia: a historical comparison. Biol Blood Marrow Transplant 2010; 17: 821-830.
37. Huang XJ, Wang Y, Liu KY, Liu DH, Xu LP, Chen H, et al. Partially matched related donor transplantation can achieve outcomes comparable to unrelated donor transplantation for patients with hematologic malignancies. Clin Cancer Res 2009; 15: 4777-4783.
38. Wang Y, Chen F, Han Y, Fu ZZ, Tang XW, Miao M, et al. Partially matched related hematopoietic stem cell transplantation without ex vivo T cell depletion compared with matched unrelated transplantation in adult patients with hematologic malignancies. Biol Blood Marrow Transplant 2009; 15: 1258-1264.