90Yttrium-hydroxyapatite: A new therapeutic option for radioactive synovectomy in haemophilic synovitis

Haemophilia

Volumn 17, Issue 5, 2011, Pages

  Thomas, S ^a,b   Gabriel, M C ^b   De Souza, S A L ^a   Gomes, S C ^c   Assi, P E ^d   Pinheiro Perri, M L ^b   Liberato, W ^d   Matushita, C S ^a   Gutfilen, B ^a   Da Fonseca, L M B ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b Ambulatorio de Hematologia ^*  (Brazil)

^c INSTITUTO OSWALDO CRUZ   (Brazil)

^d IMN   (Brazil)

Author keywords

Haemophilia; Radioactive synovectomy; Radiosynovectomy; Synovitis; Yttrium citrate; Yttrium hydroxyapatite

Indexed keywords

RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; YTTRIUM 90 CITRATE; YTTRIUM 90 HYDROXYAPATITE; CITRIC ACID; HYDROXYAPATITE; ORGANOMETALLIC COMPOUND; YTTRIUM; YTTRIUM CITRATE;

ADOLESCENT; ADULT; ARTHRALGIA; ARTICLE; CHILD; FEMALE; HEMARTHROSIS; HEMOPHILIA; HUMAN; INTERMETHOD COMPARISON; JOINT FUNCTION; JOINT RADIOGRAPHY; MAJOR CLINICAL STUDY; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; RADIOACTIVE SYNOVECTOMY; SCHOOL CHILD; SYNOVECTOMY; SYNOVITIS; BRAZIL; CLINICAL TRIAL; HEMOPHILIA A; JOINT CHARACTERISTICS AND FUNCTIONS; MULTICENTER STUDY; PAIN ASSESSMENT; RADIOGRAPHY;

ADOLESCENT; ARTHRALGIA; BRAZIL; CHILD; CITRATES; DURAPATITE; FEMALE; HEMARTHROSIS; HEMOPHILIA A; HUMANS; MALE; ORGANOMETALLIC COMPOUNDS; PAIN MEASUREMENT; RANGE OF MOTION, ARTICULAR; SYNOVITIS; YOUNG ADULT; YTTRIUM RADIOISOTOPES;

EID: 80051961127     PISSN: 13518216     EISSN: 13652516     Source Type: Journal    
DOI: 10.1111/j.1365-2516.2011.02497.x     Document Type: Article

References (27)

1. Hoots WK, Rodriguez N, Boggio L, Valentino LA. Pathogenesis of haemophilic synovitis: clinical aspects. Haemophilia 2007; 13(Suppl. 3): 4-9.
2. Salis G, Molho P, Verrier P et al. Nonsurgical synovectomy in the treatment of arthropathy in Von Willebrand's Disease. Rev Rhum Engl Ed 1998; 65: 232-7.
3. Dunn AL, Busch MT, Wyly B, Abshire TC. Radionuclide synovectomy for haemophilic arthropathy: a comprehensive review of safety and efficacy and recommendation for a standardized treatment protocol. Thromb Haemost 2002; 87: 383-93.
4. Rezende SM, Pinheiro K, Caram C, Genovez G, Barca D. Registry of inherited coagulopathies in Brazil: first report. Haemophilia 2009; 15: 142-9.
5. Gilbert MS, Cornwall R. The history of synoviorthesis in haemophilia. Haemophilia 2001; 7(Suppl. 2): 3-5.
6. Rodriguez-Merchan EC. Methods to treat chronic haemophilic synovitis. Haemophilia 2003; 9: 625-31.
7. Llinas A. The role of synovectomy in the management of a target joint. Haemophilia 2008; 14(Suppl. 3): 177-80.
8. Ahlberg A, Pettersson H. Synoviorthesis with radioactive gold in hemophiliacs. Acta Orthop Scand 1979; 50: 513-17.
9. Deutsch E, Brodack JW, Deutsch KF. Radiation synovectomy revisited. Eur J Nucl Med 1993; 20: 1113-27.
10. Chinol M, Valiabhajosula S, Goldsmith SJK et al. Chemistry and biological behavior of hydroxyapatite particles: potential radiopharmaceuticals for radiation synovectomy. J Nucl Med 1993; 34: 1113-27.
11. Silva M, Luck JV, Siegel ME. 32P chromic phosphate radiosynovectomy for chronic haemophilic synovitis. Haemophilia 2001; 7(Suppl. 2): 40-9.
12. Clunie G, Fisher M. EANM procedure guidelines for radiosynovectomy. Eur J Nucl Med Mol Imaging 2003; 30: BP 12-16.
13. Heim M, Goshen E, Amit Y, Martinowitz U. Synoviorthesis with Yttrium in haemophilia: Israel experience. Haemophilia 2001; 7(Suppl. 2): 36-9.
14. Kavakli K, Aydog S, Omay SB et al. Long-term evaluation of radioisotope synovectomy with Yttrium 90 for chronic synovitis in Turkish haemophiliacs: Izmir experience. Haemophilia 2006; 12: 28-35.
15. Kampen WU, Brenner S, Kroeger S, Sawula JA, Bohuslaviski KH, Henze E. Long term results of radiation synovectomy: a clinical follow up study. Nucl Med Commun 2001; 22: 239-46.
16. Kresnik E, Mikosch P, Gallowitsch HJ et al. Clinical outcome of radiosynoviorthesis: a meta-analysis including 2190 treated joints. Nucl Med Commun 2002; 23: 683-8.
17. van der Zant FM, Boer RO, Moolenburgh JD, Jahangier ZN, Bijlsma JW, Jacobs JW. Radiation synovectomy with (90)Yttrium, (186)Rhenium and (169)Erbium: a systematic literature review with meta-analyses. Clin Exp Rheumatol 2009; 27: 130-9.
18. 90Y-labelled particles for use in radiation synovectomy. Appl Radiat Isot 2001; 55: 471-5.
19. Santos MF, Furtado RNV, Konai MS, Castiglioni MLV, Marchetti RR, Natour J. Effectiveness of radiation synovectomy with samarium-153 particulate hydroxyapatite in rheumatoid arthritis patients with knee synovitis: a controlled randomized double-blind trial. Clinics 2009; 64: 1187-93.
20. Calegaro JU, Machado J, de Paula JC, Almeida JSC, Casularis LA. Clinical evaluation after 1year of 153-samarium hydroxyapatite synovectomy in patients with haemophilic arthropathy. Haemophilia 2009; 15: 240-6.
21. O'Duffy EK, Clunie GPR, Lui D, Edwards JCW, Ell PJ. Double blind glucocorticoid controlled trial of samarium-153 particulate hydroxyapatite radiation synovectomy for chronic knee synovitis. Ann Rheum Dis 1999; 58: 554-8.
22. Thomas S, Silva C, Assi PE et al. Synoviorthesis with Yttrium-90 in 47 hemophilic joints in Brazil. Haemophilia 2004; 10(Suppl. 3): 81.
23. Couto RM, Souza AP, Herrerias R et al. Hydroxyapatite labeled with Y-90 or Lu-177 for radiosynovectomy. Atoms for Peace 2010; 3: 19-25.
24. Thomas S, Gabriel MB, Assi PE et al. Radioactive synovectomy with Yttrium90 citrate in haemophilic synovitis: Brazilian experience. Haemophilia 2011; 17: e211-6.
25. Pettersson H, Ahlberg A, Nilsson IM. A radiologic classification of hemophilic arthropathy. Clin Orthop 1980; 149: 153-9.
26. Gilbert MS. Prophylaxis and musculoskeletal evaluation. Sem Hematol 1993; 30: 3.
27. Wallny T, Lahaye L, Brackmann HH, Heß L, Seuser A, Kraft CN. Clinical and radiographic scores in haemophilic arthropathies: how well do these correlate to subjective pain status and daily activities? Haemophilia 2002; 8: 802-8.