Antinociceptive activity of (-)-(2S,6S)-(6-ethyl-tetrahydropyran-2-yl)- formic acid on acute pain in mice

Behavioural Pharmacology

Volumn 22, Issue 5-6, 2011, Pages 564-572

  Marinho, Bruno Guimarães ^a   Miranda, Leandro S M ^a   Meireles, Bruno A ^a   Vasconcellos, Mário L A A ^b   Matheus, Maria E ^a   Pereira, Vera L P ^a   Fernandes, Patricia D ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b FEDERAL UNIVERSITY OF PARAÍBA   (Brazil)

Author keywords

antinociception; morphine; mouse; opioid; pain; tetrahydropyran derivative

Indexed keywords

(6 ETHYLTETRAHYDROPYRAN 2 YL)FORMIC ACID; ACETIC ACID; FORMALDEHYDE; FORMIC ACID DERIVATIVE; MORPHINE; NALOXONE; TETRAHYDROPYRAN DERIVATIVE; UNCLASSIFIED DRUG;

ACUTE DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG DOSE COMPARISON; DRUG MECHANISM; DRUG SYNTHESIS; DRUG TOLERANCE; HOT PLATE TEST; MALE; MOUSE; NONHUMAN; OPEN FIELD BEHAVIOR; PAIN; TAIL FLICK TEST;

ACUTE PAIN; ANALGESICS; ANALGESICS, OPIOID; ANIMALS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; FORMIC ACIDS; MALE; MICE; MORPHINE; NALOXONE; NARCOTIC ANTAGONISTS; PYRANS;

EID: 80051948533     PISSN: 09558810     EISSN: 14735849     Source Type: Journal    
DOI: 10.1097/FBP.0b013e3283474a1b     Document Type: Article

References (29)

1. Adams LL, Gatchel RJ, Robinson RC, Polatin P, Gajraj N, Deschner M, et al. (2004). Development of a self-report screening instrument for assessing potential opioid medication misuse in chronic pain patients. J Pain Symptom Manage 27:440-459. (Pubitemid 38569650)
2. Barros HMT, Tannhauser MAL, Tannhauser SL, Tannhauser M (1991). Enhanced detection of hyperactivity after drug withdrawal with a simple modification of the open-field apparatus. J Pharmacol Meth 26:269-275.
3. Ben-Bassat J, Peretz E, Sulman FG (1959). Analgesimetry and ranking of analgesic drugs by the receptacle method. Archs Int Pharmachodyn Ther 122:434-447.
4. Bradberry JC, Raebel MA (1981). Continuous infusion of naloxone in the treatment of narcotic overdose. Drug Intell Clin Pharm 15:945-950. (Pubitemid 12186901)
5. Bruera E, Palmer L, Bosjak S, Rico MA, Moyano J, Sweeney C, et al. (2004). Methadone versus morphine as a first-line strong opioid for cancer pain: a randomized, double-blind study. J Clin Oncol 22:185-192. (Pubitemid 41095131)
6. Butler SF, Budman SH, Fernandez K, Jamison RN (2004). Validation of a screener and opioid assessment measure for patients with chronic pain. Pain 112:65-75. (Pubitemid 39371021)
7. Collier HO, Dinneen LC, Johnson CA, Schneider C (1968). The abdominal constriction response and its suppression by analgesic drugs in the mouse. Br J Pharmacol Chemother 32:295-310.
8. Cowan DT, Allan L, Griffiths PA (2002). Pilot study into the problematic use of opioid analgesics in chronic non-cancer pain patients. Int J Nurse Study 39:59-69. (Pubitemid 40433406)
9. Dray A, Urban L, Dickenson A (1994). Pharmacology of chronic pain. Trends Pharmacol Sci 15:190-197. (Pubitemid 24196181)
10. Gene RM, Segura L, Adzet T, Marin E, Inglesias J (1998). Heterotheca inuloides: antiinflammatory and analgesic effects. J Ethnopharmacol 60:157-162. (Pubitemid 28143726)
11. Gharagozlou P, Demirci H, Clark D, Lameh J (2003). Activity of opioid ligands on cells expressing cloned mu opioid receptors. BMC Pharmacol 3:1-8.
12. Gilson AM, Ryan KM, Joranson DE, Dahl JL (2004). A reassessment of trends in the medical use and abuse of opioid analgesics and implications for diversion control: 1997-2002. J Pain Symp Manag 28:176-188. (Pubitemid 38970078)
13. Handal KA, Schauben JL, Salamone FR (1983). Naloxone. Ann Emerg Med 12:438-445. (Pubitemid 13064831)
14. Hunskaar S, Hole K (1987). The formalin test in mice: dissociation between inflammatory and non-inflammatory pain. Pain 30:103-114. (Pubitemid 17094194)
15. Hunskaar S, Berge OG, Hole K (1986). Dissociation between antinociceptive an anti-inflammatory effects of acetylsalicylic and indomethacin in the formalin test. Pain 25:125-132. (Pubitemid 16104250)
16. Kuraishi Y, Harada Y, Aratani S, Satoh M, Takagi H (1983). Separate involvement of the spinal noradrenergic and serotonergic systems in morphine analgesia: the differences in mechanical and thermal algesic tests. Brain Res 273:245-252. (Pubitemid 13039713)
17. Kuraishi Y, Hirota N, Satoh M, Takagi H (1985). Antinociceptive effects of intrathecal opioids, noradrenaline and serotonin in rats: mechanical and thermal algesic tests. Brain Res 326:168-171. (Pubitemid 15160024)
18. MacPherson RD (2000). The pharmacological basis of contemporary pain management. Pharmacol Therap 88:163-185. (Pubitemid 32057138)
19. Mazzoccato C, Sweeney C, Bruera M (2001). Clinical research in palliative care. Palliat Med 115:261-264.
20. Miranda LSM, Meireles BA, Costa JS, Pereira VLP, Vasconcellos MLAA (2005). First enantioselective synthesis of (+)(2S,6S)-(6-Ethyltetrahydropyran- 2-yl) formic acid. Synlett 5:869-871. (Pubitemid 40445804)
21. Peckham EM, Traynor JR (2006). Comparison of the antinociceptive response to morphine and morphine-like compounds in male and female Sprague-Dawley rats. J Pharmacol Exp Ther 316:1195-1201. (Pubitemid 43345294)
22. Ramabadran K, Bansinath M, Turndorf H, Puig MM (1989). Tail immersion test for the evaluation of a nociceptive reaction in mice. Methodological considerations. J Pharmacol Methods 21:21-31. (Pubitemid 19064683)
23. Sahley TL, Berntson GG (1979). Antinociceptive effects of central and systemic administration of nicotine in the rat. Psychopharmacology 65:279-283. (Pubitemid 10194755)
24. Sirohi S, Dighe SV, Walker EA, Yoburn BC (2008). The analgesic efficacy of fentanyl: Relationship to tolerance and m-opioid receptor regulation. Pharmacol Biochem Behav 23:508-604.
25. Srinivasan K, Muruganandan S, Lal J, Chandra S,Tandan SK, Raviprakash V, et al. (2003). Antinoniceptive and antipyretic activities of Pongamia pinnata leaves. Phytother Res 17:259-264. (Pubitemid 36406758)
26. Tjolsen A, Berge OG, Hunskaar S, Rosland JH, Hole K (1992). The formalin test: an evaluation of the method. Pain 51:5-17.
27. Trongsakul S, Panthong A, Kanjanapothi D, Taesotikul T (2003). The analgesic, antipyretic and anti-inflammatory activity of Diospyros variegata Kruz. J Ethnopharmacol 85:221-225.
28. Yaksh TL, Rudy TA (1977). Studies on direct spinal action of narcotics in production of analgesia in rat. J Pharmacol Exp Ther 202:411-428. (Pubitemid 8168205)
29. Whittle BA (1964). The use of changes in capillary permeability in mice to distinguish between narcotic and non-narcotic analgesics. Br J Pharmacol 22:246-253.