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Volumn 15, Issue 3, 2011, Pages 573-583

Management of the Treatment-Experienced Patient Infected with Hepatitis C Virus Genotype 1: Options and Considerations

Author keywords

Boceprevir; Consensus interferon; Difficult to treat patients; Genotype 1; Hepatitis C; IL 28B polymorphism; NS3 protease inhibitor; Telaprevir

Indexed keywords

BOCEPREVIR; NONSTRUCTURAL PROTEIN 3; PEGINTERFERON; PROTEINASE INHIBITOR; RIBAVIRIN; TELAPREVIR;

EID: 80051939682     PISSN: 10893261     EISSN: 15578224     Source Type: Journal    
DOI: 10.1016/j.cld.2011.05.001     Document Type: Review
Times cited : (1)

References (33)
  • 1
    • 0033584440 scopus 로고    scopus 로고
    • The prevalence of hepatitis C virus infection in the United States, 1988 through 1994
    • Alter M.J., Kruszon-Moran D., Nainan O.V., et al. The prevalence of hepatitis C virus infection in the United States, 1988 through 1994. N Engl J Med 1999, 341(8):556-562.
    • (1999) N Engl J Med , vol.341 , Issue.8 , pp. 556-562
    • Alter, M.J.1    Kruszon-Moran, D.2    Nainan, O.V.3
  • 2
    • 0033544499 scopus 로고    scopus 로고
    • Hepatitis C-global prevalence
    • WHO
    • Hepatitis C-global prevalence. Wkly Epidemiol Rec 1999, 49:425-427. WHO.
    • (1999) Wkly Epidemiol Rec , vol.49 , pp. 425-427
  • 3
    • 0035811625 scopus 로고    scopus 로고
    • Hepatitis C virus infection
    • Lauer M.G., Walker D.B. Hepatitis C virus infection. N Engl J Med 2001, 345(1):41-52.
    • (2001) N Engl J Med , vol.345 , Issue.1 , pp. 41-52
    • Lauer, M.G.1    Walker, D.B.2
  • 4
    • 44449146437 scopus 로고    scopus 로고
    • Consensus interferon and ribavirin in patients with chronic hepatitis C who were nonresponders to pegylated interferon alfa-2b and ribavirin
    • Leevy C.B. Consensus interferon and ribavirin in patients with chronic hepatitis C who were nonresponders to pegylated interferon alfa-2b and ribavirin. Dig Dis Sci 2008, 53:1961-1966.
    • (2008) Dig Dis Sci , vol.53 , pp. 1961-1966
    • Leevy, C.B.1
  • 5
    • 0030470531 scopus 로고    scopus 로고
    • Predictors of response to interferon therapy
    • Saracco G., Rizzetto M. Predictors of response to interferon therapy. Dig Dis Sci 1996, 41:115S-120S.
    • (1996) Dig Dis Sci , vol.41
    • Saracco, G.1    Rizzetto, M.2
  • 6
    • 1642546905 scopus 로고    scopus 로고
    • Pegylated interferon alpha2b plus ribavirin for the treatment of chronic hepatitis C in HIV infected patients
    • Moreno L., Quereda C., Moreno A., et al. Pegylated interferon alpha2b plus ribavirin for the treatment of chronic hepatitis C in HIV infected patients. AIDS 2004, 18:67-73.
    • (2004) AIDS , vol.18 , pp. 67-73
    • Moreno, L.1    Quereda, C.2    Moreno, A.3
  • 7
    • 17344369924 scopus 로고    scopus 로고
    • Risk factors for hepatocellular carcinoma and its incidence after interferon treatment in patients with chronic hepatitis C
    • Kasahara A., Hayashi N., Mochizuki K., et al. Risk factors for hepatocellular carcinoma and its incidence after interferon treatment in patients with chronic hepatitis C. Hepatology 1998, 27:1394-1402.
    • (1998) Hepatology , vol.27 , pp. 1394-1402
    • Kasahara, A.1    Hayashi, N.2    Mochizuki, K.3
  • 8
    • 0033520109 scopus 로고    scopus 로고
    • Interferon therapy reduces the risk for hepatocellular carcinoma: national surveillance program of cirrhotic and non-cirrhotic patients with chronic hepatitis C in Japan
    • Yoshida H., Shiratori Y., Moriyama M., et al. Interferon therapy reduces the risk for hepatocellular carcinoma: national surveillance program of cirrhotic and non-cirrhotic patients with chronic hepatitis C in Japan. Ann Intern Med 1999, 131:174-181.
    • (1999) Ann Intern Med , vol.131 , pp. 174-181
    • Yoshida, H.1    Shiratori, Y.2    Moriyama, M.3
  • 9
    • 66949176133 scopus 로고    scopus 로고
    • Retreating chronic hepatitis C with daily interferon Alfacon-1/ribavirin after nonresponse to pegylated interferon/ribavirin: direct results
    • Bacon B.R., Shiffman M.L., Mendes F., et al. Retreating chronic hepatitis C with daily interferon Alfacon-1/ribavirin after nonresponse to pegylated interferon/ribavirin: direct results. Hepatology 2009, 49:1838-1846.
    • (2009) Hepatology , vol.49 , pp. 1838-1846
    • Bacon, B.R.1    Shiffman, M.L.2    Mendes, F.3
  • 10
    • 79958816097 scopus 로고    scopus 로고
    • Rapid virological response is the most important predictor of sustained virological response across genotypes in patients with chronic hepatitis C virus infection
    • [Epub ahead of print]
    • Fried M.W., Hadziyannis S.J., Shiffman M.L., et al. Rapid virological response is the most important predictor of sustained virological response across genotypes in patients with chronic hepatitis C virus infection. J Hepatol 2011, [Epub ahead of print].
    • (2011) J Hepatol
    • Fried, M.W.1    Hadziyannis, S.J.2    Shiffman, M.L.3
  • 11
    • 65449127754 scopus 로고    scopus 로고
    • A step forward in therapy for hepatitis C
    • Hoofnagle J.H. A step forward in therapy for hepatitis C. N Engl J Med 2009, 360(18):1899-1901.
    • (2009) N Engl J Med , vol.360 , Issue.18 , pp. 1899-1901
    • Hoofnagle, J.H.1
  • 12
    • 0037179698 scopus 로고    scopus 로고
    • Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection
    • Fried M.W., Shiffman M.L., Reddy K.R., et al. Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection. N Engl J Med 2002, 347:975-982.
    • (2002) N Engl J Med , vol.347 , pp. 975-982
    • Fried, M.W.1    Shiffman, M.L.2    Reddy, K.R.3
  • 13
    • 0035934568 scopus 로고    scopus 로고
    • Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomized trial
    • Manns M.P., McHutchison J.G., Gordon S.C., et al. Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomized trial. Lancet 2001, 358:958-965.
    • (2001) Lancet , vol.358 , pp. 958-965
    • Manns, M.P.1    McHutchison, J.G.2    Gordon, S.C.3
  • 14
    • 1542378867 scopus 로고    scopus 로고
    • Peginterferon alfa-2a (40 kilodaltons) and ribavirin combination therapy in chronic hepatitis C: a randomized study of the effect of treatment duration and ribavirin dose
    • Hadziyannis S.J., Sette H., Morgan T.R., et al. Peginterferon alfa-2a (40 kilodaltons) and ribavirin combination therapy in chronic hepatitis C: a randomized study of the effect of treatment duration and ribavirin dose. Ann Intern Med 2004, 140:346-355.
    • (2004) Ann Intern Med , vol.140 , pp. 346-355
    • Hadziyannis, S.J.1    Sette, H.2    Morgan, T.R.3
  • 15
    • 33746535101 scopus 로고    scopus 로고
    • Peginterferon and ribavirin treatment in African American and Caucasian American patients with hepatitis C genotype 1
    • Conjeevaram H.S., Fried M.W., Jeffers L.J., et al. Peginterferon and ribavirin treatment in African American and Caucasian American patients with hepatitis C genotype 1. Gastroenterology 2006, 131:470-477.
    • (2006) Gastroenterology , vol.131 , pp. 470-477
    • Conjeevaram, H.S.1    Fried, M.W.2    Jeffers, L.J.3
  • 16
    • 58349122475 scopus 로고    scopus 로고
    • Peginterferon alfa-2a and ribavirin in Latino and non-Latino whites with hepatitis C
    • Rodriguez-Torres M., Jeffers L.J., Sheikh M.Y., et al. Peginterferon alfa-2a and ribavirin in Latino and non-Latino whites with hepatitis C. N Engl J Med 2009, 360:257-267.
    • (2009) N Engl J Med , vol.360 , pp. 257-267
    • Rodriguez-Torres, M.1    Jeffers, L.J.2    Sheikh, M.Y.3
  • 17
    • 65449136656 scopus 로고    scopus 로고
    • Diagnosis, management, and treatment of hepatitis C: an update
    • Ghany G.M., Strader B.D., Thomas L.D., et al. Diagnosis, management, and treatment of hepatitis C: an update. Hepatology 2009, 49(4):1335-1374.
    • (2009) Hepatology , vol.49 , Issue.4 , pp. 1335-1374
    • Ghany, G.M.1    Strader, B.D.2    Thomas, L.D.3
  • 18
    • 67349172961 scopus 로고    scopus 로고
    • Peginterferon alfa-2b and ribavirin: effective in patients with hepatitis C who failed interferon alfa/ribavirin therapy
    • Poynard T., Colombo M., Bruix J., et al. Peginterferon alfa-2b and ribavirin: effective in patients with hepatitis C who failed interferon alfa/ribavirin therapy. Gastroenterology 2009, 136:1618-1628.
    • (2009) Gastroenterology , vol.136 , pp. 1618-1628
    • Poynard, T.1    Colombo, M.2    Bruix, J.3
  • 19
    • 65349129985 scopus 로고    scopus 로고
    • Re-treatment of patients with chronic hepatitis C who do not respond to peginterferon-alfa2b
    • Jensen D.M., Marcellin P., Freilich B., et al. Re-treatment of patients with chronic hepatitis C who do not respond to peginterferon-alfa2b. Ann Intern Med 2009, 150:528-540.
    • (2009) Ann Intern Med , vol.150 , pp. 528-540
    • Jensen, D.M.1    Marcellin, P.2    Freilich, B.3
  • 20
    • 54349104458 scopus 로고    scopus 로고
    • Retreatment of HCV genotype 1 relapse patients to peginterferon/ribavirin therapy with an extended treatment regimen of 72 weeks with consensus interferon/ribavirin versus peginterferon alpha/ribavirin
    • Kaiser S., Lutze B., Sauter B., et al. Retreatment of HCV genotype 1 relapse patients to peginterferon/ribavirin therapy with an extended treatment regimen of 72 weeks with consensus interferon/ribavirin versus peginterferon alpha/ribavirin. Hepatology 2007, 46(4 SUPPL 1):819.
    • (2007) Hepatology , vol.46 , Issue.4 SUPPL 1 , pp. 819
    • Kaiser, S.1    Lutze, B.2    Sauter, B.3
  • 21
    • 77953881002 scopus 로고    scopus 로고
    • Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in the genotype 1 hepatitis C virus
    • Thompson A.J., Muir A.J., Sulkowski M.S., et al. Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in the genotype 1 hepatitis C virus. Gastroenterology 2010, 139:120-129.
    • (2010) Gastroenterology , vol.139 , pp. 120-129
    • Thompson, A.J.1    Muir, A.J.2    Sulkowski, M.S.3
  • 22
    • 79960449077 scopus 로고    scopus 로고
    • IL28B polymorphism predicts virologic response in patients with hepatitis C genotype 1 treated with boceprevir (BOC) combination therapy
    • Poordad F., Bronowicki J.P., Gordon S.C., et al. IL28B polymorphism predicts virologic response in patients with hepatitis C genotype 1 treated with boceprevir (BOC) combination therapy. J Hepatol 2011, 54:S6.
    • (2011) J Hepatol , vol.54
    • Poordad, F.1    Bronowicki, J.P.2    Gordon, S.C.3
  • 23
    • 77956268467 scopus 로고    scopus 로고
    • Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial
    • Kwo P.Y., Lawitz E.J., McCone J., et al. Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial. Lancet 2010, 376(9742):705-716.
    • (2010) Lancet , vol.376 , Issue.9742 , pp. 705-716
    • Kwo, P.Y.1    Lawitz, E.J.2    McCone, J.3
  • 24
    • 67650523017 scopus 로고    scopus 로고
    • Boceprevir, an NS3 protease inhibitor of HCV
    • Berman K., Kwo P.Y. Boceprevir, an NS3 protease inhibitor of HCV. Clin Liver Dis 2009, 13(3):429-439.
    • (2009) Clin Liver Dis , vol.13 , Issue.3 , pp. 429-439
    • Berman, K.1    Kwo, P.Y.2
  • 25
    • 65449152185 scopus 로고    scopus 로고
    • Telaprevir with peginterferon and ribavirin for chronic HCV genotype 1 infection
    • McHutchison J.G., Everson G.T., Gordon S.C., et al. Telaprevir with peginterferon and ribavirin for chronic HCV genotype 1 infection. N Engl J Med 2009, 360:1827-1838.
    • (2009) N Engl J Med , vol.360 , pp. 1827-1838
    • McHutchison, J.G.1    Everson, G.T.2    Gordon, S.C.3
  • 26
    • 65449171953 scopus 로고    scopus 로고
    • Telaprevir and peginterferon with or without ribavirin for chronic HCV infection
    • Hézode C., Forestier N., Dusheiko G., et al. Telaprevir and peginterferon with or without ribavirin for chronic HCV infection. N Engl J Med 2009, 360:1839-1850.
    • (2009) N Engl J Med , vol.360 , pp. 1839-1850
    • Hézode, C.1    Forestier, N.2    Dusheiko, G.3
  • 27
    • 80051922228 scopus 로고    scopus 로고
    • Telaprevir in combination with peginterferon alfa2a and ribavirin for 24 or 48 weeks in treatment-naive genotype 1 HCV patients who achieved an extended rapid viral response: final results of phase 3 ILLUMINATE study. 61st AASLD; Boston (MA), October 29 to November 2010. Hepatology 2010;52:106A.
    • Sherman KE, Flamm SL, Afdhal NH. Telaprevir in combination with peginterferon alfa2a and ribavirin for 24 or 48 weeks in treatment-naive genotype 1 HCV patients who achieved an extended rapid viral response: final results of phase 3 ILLUMINATE study. 61st AASLD; Boston (MA), October 29 to November 2010. Hepatology 2010;52:106A.
    • (2010)
    • Sherman, K.E.1    Flamm, S.L.2    Afdhal, N.H.3
  • 28
    • 80051928331 scopus 로고    scopus 로고
    • Telaprevir in combination with peginterferon and ribavirin in genotype 1 HCV treatment-naive patients: final results of phase 3 ADVANCE study. 61st AASLD; Boston (MA), October 29 to November 2010. Hepatology 2010;52:427A.
    • Jacobson IM, McHutchison GJ, Dusheiko MG. Telaprevir in combination with peginterferon and ribavirin in genotype 1 HCV treatment-naive patients: final results of phase 3 ADVANCE study. 61st AASLD; Boston (MA), October 29 to November 2010. Hepatology 2010;52:427A.
    • (2010)
    • Jacobson, I.M.1    McHutchison, G.J.2    Dusheiko, M.G.3
  • 29
    • 77950817619 scopus 로고    scopus 로고
    • Telaprevir for previously treated chronic HCV infection
    • McHutchison J.G., Manns M.P., Muir A.J., et al. Telaprevir for previously treated chronic HCV infection. N Engl J Med 2010, 362:1292-1303.
    • (2010) N Engl J Med , vol.362 , pp. 1292-1303
    • McHutchison, J.G.1    Manns, M.P.2    Muir, A.J.3
  • 30
    • 79953173221 scopus 로고    scopus 로고
    • Boceprevir with peginterferon/ribavirin for untreated chronic hepatitis C
    • Poordad F., McCone J., Bacon B.R., et al. Boceprevir with peginterferon/ribavirin for untreated chronic hepatitis C. N Engl J Med 2011, 54:1195-1206.
    • (2011) N Engl J Med , vol.54 , pp. 1195-1206
    • Poordad, F.1    McCone, J.2    Bacon, B.R.3
  • 31
    • 79953176289 scopus 로고    scopus 로고
    • Boceprevir for treatment of chronic hepatitis C genotype 1 nonresponders
    • Bacon B.R., Gordon S.C., Lawitz E., et al. Boceprevir for treatment of chronic hepatitis C genotype 1 nonresponders. N Engl J Med 2011, 54:1207-1217.
    • (2011) N Engl J Med , vol.54 , pp. 1207-1217
    • Bacon, B.R.1    Gordon, S.C.2    Lawitz, E.3
  • 32
    • 80051924652 scopus 로고    scopus 로고
    • Telaprevir-based therapy in genotype 1 hepatitis C virus-infected patients with prior null response, partial response or relapse to peginterferon/ribavirin: REALIZE Trial Final Results. Oral presentation, Asia Pacific Association for the Study of Liver, Bangkok (Thailand), February 18
    • Foster GW, Zeuzem S, Andreone P, et al. Telaprevir-based therapy in genotype 1 hepatitis C virus-infected patients with prior null response, partial response or relapse to peginterferon/ribavirin: REALIZE Trial Final Results. Oral presentation, Asia Pacific Association for the Study of Liver, Bangkok (Thailand), February 18, 2011.
    • (2011)
    • Foster, G.W.1    Zeuzem, S.2    Andreone, P.3
  • 33
    • 79551525326 scopus 로고    scopus 로고
    • Big changes are coming in hepatitis C
    • Poordad F. Big changes are coming in hepatitis C. Curr Gastroenterol Rep 2011, 13(1):72-77.
    • (2011) Curr Gastroenterol Rep , vol.13 , Issue.1 , pp. 72-77
    • Poordad, F.1


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