Toxicity study in juvenile rats with the α 4β 2 nicotinic acetylcholine receptor partial agonist CP-601,927

Birth Defects Research Part B - Developmental and Reproductive Toxicology

Volumn 92, Issue 4, 2011, Pages 323-332

  Campion, Sarah N ^a   Hurtt, Mark E ^a   Chatman, Linda A ^a   Cappon, Gregg D ^a  

^a PFIZER INC   (United States)

Author keywords

Juvenile; Learning and memory; Nicotinic; Rat; Toxicity

Indexed keywords

CP 601927; NICOTINIC RECEPTOR ALPHA4BETA2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CENTRAL NERVOUS SYSTEM FUNCTION; CONTROLLED STUDY; DRUG EFFECT; DRUG EXPOSURE; EXPERIMENTAL TEST; FEMALE; FERTILITY; JUVENILE ANIMAL; LATENT PERIOD; LEARNING; MALE; MATING; MEMORY; MOTOR ACTIVITY; NONHUMAN; ORGAN WEIGHT; POSTNATAL DEVELOPMENT; POSTNATAL GROWTH; PRIORITY JOURNAL; RAT; SEXUAL MATURATION; SPERMATOZOON COUNT; SPERMATOZOON MOTILITY; TOXICITY; TOXICOKINETICS;

ABNORMALITIES, DRUG-INDUCED; ANIMALS; BEHAVIOR, ANIMAL; BODY WEIGHT; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG PARTIAL AGONISM; FEMALE; LEARNING; MALE; MEMORY; NICOTINIC AGONISTS; ORGAN SIZE; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NICOTINIC; REPRODUCTION;

ANIMALIA; RATTUS;

EID: 80051937122     PISSN: 15429733     EISSN: 15429741     Source Type: Journal    
DOI: 10.1002/bdrb.20298     Document Type: Article

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