Oral contraceptive use, iron stores and vascular endothelial function in healthy women

Contraception

Volumn 84, Issue 3, 2011, Pages 285-290

  Friedman, Julie ^a   Cremer, Miriam ^b   Jelani, Qurat Ul Ain ^a   Huang, Xi ^a   Jian, Jinlong ^a   Shah, Sooraj ^a   Katz, Stuart D ^a  

^a NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Iron; Oral contraceptive pills; Progestins; Vascular endothelium

Indexed keywords

BIOLOGICAL MARKER; DROSPIRENONE; ESTRANE DERIVATIVE; ESTROGEN; FERRITIN; GONANE DERIVATIVE; HEMOGLOBIN; IRON; ORAL CONTRACEPTIVE AGENT; TRANSFERRIN;

ADULT; ARTICLE; BLOOD FLOW; BLOOD FLOW VELOCITY; BLOOD SAMPLING; BRACHIAL ARTERY; CARDIOVASCULAR FUNCTION; CARDIOVASCULAR RISK; CLINICAL ASSESSMENT; CROSS-SECTIONAL STUDY; DRUG EXPOSURE; FEMALE; FERRITIN BLOOD LEVEL; FLOW MEDIATED DILATION; HUMAN; IRON BINDING CAPACITY; IRON BLOOD LEVEL; IRON STORAGE; MULTIVARIATE ANALYSIS; NORMAL HUMAN; ORAL CONTRACEPTION; PREDICTOR VARIABLE; TREATMENT DURATION; VASCULAR ENDOTHELIAL FUNCTION;

ADULT; ANDROSTENES; BLOOD FLOW VELOCITY; BRACHIAL ARTERY; CARDIOVASCULAR DISEASES; CONTRACEPTIVES, ORAL; CROSS-SECTIONAL STUDIES; ENDOTHELIUM, VASCULAR; ESTRANES; FEMALE; FERRITINS; GONANES; HUMANS; IRON; LINEAR MODELS; VASODILATION; YOUNG ADULT;

EID: 80051901444     PISSN: 00107824     EISSN: 18790518     Source Type: Journal    
DOI: 10.1016/j.contraception.2011.01.012     Document Type: Article

References (33)

1. Shufelt C.L., and Bairey Merz C.N. Contraceptive hormone use and cardiovascular disease J Am Coll Cardiol 53 2009 221 231
2. Sullivan J.L. Iron and the sex difference in heart disease risk Lancet 1 1981 1293 1294 (Pubitemid 11111356)
3. Sullivan J.L. Is stored iron safe? J Lab Clin Med 144 2004 280 284 (Pubitemid 40018014)
4. Frassinelli-Gunderson E.P., Margen S., and Brown J.R. Iron stores in users of oral contraceptive agents Am J Clin Nutr 41 1985 703 712 (Pubitemid 15092877)
5. Milman N., Kirchhoff M., and Jorgensen T. Iron status markers, serum ferritin and hemoglobin in 1359 Danish women in relation to menstruation, hormonal contraception, parity, and postmenopausal hormone treatment Ann Hematol 65 1992 96 102
6. Davignon J., and Ganz P. Role of endothelial dysfunction in atherosclerosis Circulation 109 2004 III27 III32
7. Katz S.D., Hryniewicz K., and Hriljac I. Vascular endothelial dysfunction and mortality risk in patients with chronic heart failure Circulation 111 2005 310 314 (Pubitemid 40165337)
8. Zheng H., Cable R., Spencer B., Votto N., and Katz S.D. Iron stores and vascular function in voluntary blood donors Arterioscler Thromb Vasc Biol 25 2005 1577 1583 (Pubitemid 41098924)
9. Zheng H., Dimayuga C., Hudaihed A., and Katz S.D. Effect of dexrazoxane on homocysteine-induced endothelial dysfunction in normal subjects Arterioscler Thromb Vasc Biol 22 2002 E15 18
10. Zheng H., Huang X., Zhang Q., and Katz S.D. Iron sucrose augments homocysteine-induced endothelial dysfunction in normal subjects Kidney Int 69 2006 679 684 (Pubitemid 43237636)
11. Arnal J.F., Fontaine C., and Billon-Gales A. Estrogen receptors and endothelium Arterioscler Thromb Vasc Biol 30 2010 1506 1512
12. Torgrimson B.N., Meendering J.R., Kaplan P.F., and Minson C.T. Endothelial function across an oral contraceptive cycle in women using levonorgestrel and ethinyl estradiol Am J Physiol Heart Circ Physiol 292 2007 H2874 H2880
13. Herrington D.M., Espeland M.A., and Crouse J.R. 3rd Estrogen replacement and brachial artery flow-mediated vasodilation in older women Arterioscler Thromb Vasc Biol 21 2001 1955 1961 (Pubitemid 34219747)
14. Gilligan D.M., Badar D.M., Panza J.A., Quyyumi A.A., and Cannon R.O. Acute vascular effects of estrogen in postmenopausal women Circulation 90 1994 786 791 (Pubitemid 24242746)
15. Virdis A., Ghiadoni L., and Pinto S. Mechanisms responsible for endothelial dysfunction associated with acute estrogen deprivation in normotensive women Circulation 101 2000 2258 2263 (Pubitemid 30317127)
16. Koh K.K., Jin D.K., and Yang S.H. Vascular effects of synthetic or natural progestagen combined with conjugated equine estrogen in healthy postmenopausal women Circulation 103 2001 1961 1966 (Pubitemid 32322223)
17. Virdis A., Pinto S., and Versari D. Effect of oral contraceptives on endothelial function in the peripheral microcirculation of healthy women J Hypertens 21 2003 2275 2280 (Pubitemid 38293566)
18. Meendering J.R., Torgrimson B.N., Miller N.P., Kaplan P.F., and Minson C.T. Estrogen, medroxyprogesterone acetate, endothelial function, and biomarkers of cardiovascular risk in young women Am J Physiol Heart Circ Physiol 294 2008 H1630 H1637
19. Meendering J.R., Torgrimson B.N., Miller N.P., Kaplan P.F., and Minson C.T. Ethinyl estradiol-to-desogestrel ratio impacts endothelial function in young women Contraception 79 2009 41 49
20. Sitruk-Ware R. Pharmacological profile of progestins Maturitas 47 2004 277 283 (Pubitemid 38523308)
21. Stanczyk F.Z. All progestins are not created equal Steroids 68 2003 879 890 (Pubitemid 37532412)
22. Sitruk-Ware R. Pharmacology of different progestogens: the special case of drospirenone Climacteric 8 Suppl 3 2005 4 12 (Pubitemid 41608058)
23. Simoncini T., Fu X.D., and Caruso A. Drospirenone increases endothelial nitric oxide synthesis via a combined action on progesterone and mineralocorticoid receptors Hum Reprod 22 2007 2325 2334 (Pubitemid 47241881)
24. J.R. Meendering, B.N. Torgrimson, N.P. Miller, P.F. Kaplan, and C.T. Minson A combined oral contraceptive containing 30 mcg ethinyl estradiol and 3.0 mg drospirenone does not impair endothelium-dependent vasodilation Contraception 82 2010 366 372
25. Farquharson C.A., and Struthers A.D. Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure Circulation 101 2000 594 597 (Pubitemid 30094728)
26. Imanishi T., Ikejima H., and Tsujioka H. Addition of eplerenone to an angiotensin-converting enzyme inhibitor effectively improves nitric oxide bioavailability Hypertension 51 2008 734 741 (Pubitemid 351301528)
27. Stuckey R., Aldridge T., and Lim F.L. Induction of iron homeostasis genes during estrogen-induced uterine growth and differentiation Mol Cell Endocrinol 253 2006 22 29 (Pubitemid 43946565)
28. Gordon T., Kannel W.B., Hjortland M.C., and McNamara P.M. Menopause and coronary heart disease. The Framingham Study Ann Intern Med 89 1978 157 161 (Pubitemid 8395464)
29. Araujo J.A., Romano E.L., and Brito B.E. Iron overload augments the development of atherosclerotic lesions in rabbits Arterioscler Thromb Vasc Biol 15 1995 1172 1180
30. Zweier J.L., Broderick R., Kuppusamy P., Thompson-Gorman S., and Lutty G.A. Determination of the mechanism of free radical generation in human aortic endothelial cells exposed to anoxia and reoxygenation J Biol Chem 269 1994 24156 24162 (Pubitemid 24300954)
31. Zacharski L.R., Chow B.K., and Howes P.S. Reduction of iron stores and cardiovascular outcomes in patients with peripheral arterial disease: a randomized controlled trial JAMA 297 2007 603 610
32. Goldzieher J.W., and Stanczyk F.Z. Oral contraceptives and individual variability of circulating levels of ethinyl estradiol and progestins Contraception 78 2008 4 9
33. Anderson F.D., and Hait H. A multicenter, randomized study of an extended cycle oral contraceptive Contraception 68 2003 89 96 (Pubitemid 37101032)