Characterization, epitope identification and mechanisms of the anti-septic capacity of monoclonal antibodies against macrophage migration inhibitory factor

International Immunopharmacology

Volumn 11, Issue 9, 2011, Pages 1333-1340

  Zhang, Yang ^a   Zeng, Xiaogang ^b   Chen, Sha ^a   Zhang, Zhujun ^a   Li, Peng ^a   Yi, Weijing ^a   Huang, Hongtao ^c   Yao, Jing ^c   Li, Shuhui ^a   Hu, Chuanmin ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b Chongqing Infections Disease Medical Center   (China)

^c Building B   (China)

Author keywords

Epitope; Macrophage migration inhibitory factor (MIF); Monoclonal antibody; Sepsis; Tautomerase

Indexed keywords

IMMUNOGLOBULIN G ANTIBODY; INTERLEUKIN 6; MACROPHAGE MIGRATION INHIBITION FACTOR; MACROPHAGE MIGRATION INHIBITORY FACTOR MONOCLONAL ANTIBODY F11; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ANTIGEN BINDING; ANTIGEN DETECTION; ANTIGEN RECOGNITION; ANTISEPSIS; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG POTENCY; ENZYME INHIBITION; EXPERIMENTAL MODEL; FEMALE; HISTOPATHOLOGY; IN VIVO STUDY; MOUSE; NONHUMAN; PERITONITIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; SEPSIS; SURVIVAL RATE;

ANIMALS; ANTIBODIES, MONOCLONAL; CECUM; CELL LINE; CELL LINE, TUMOR; EPITOPE MAPPING; EPITOPES; FEMALE; IMMUNOGLOBULIN G; INTERLEUKIN-6; KIDNEY; LUNG; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PERITONITIS; RECOMBINANT PROTEINS; SEPSIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80051889422     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2011.04.017     Document Type: Article

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