Aqueous methanol extracts of Cochlospermum tinctorium (A. Rich) possess analgesic and anti-inflammatory activities

Journal of Young Pharmacists

Volumn 3, Issue 3, 2011, Pages 237-242

  Ahmed, T S ^a   Magaji, M G ^b   Yaro, A H ^c   Musa, A M ^b   Adamu, A K ^b  

^a Federal Government Girls College   (Nigeria)

^b AHMADU BELLO UNIVERSITY   (Nigeria)

^c BAYERO UNIVERSITY   (Nigeria)

Author keywords

Analgesia; Anti inflammation; Cochlopermum tinctorium; Edema; Hot plate; Writhing

Indexed keywords

ACETIC ACID; ALKALOID; CARRAGEENAN; COCHLOSPERMUM TINCTORIUM EXTRACT; FLAVONOID; HERBACEOUS AGENT; KETOPROFEN; METHANOL; PLANT GLYCOSIDE; SAPONIN; STEROID; TANNIN; TERPENOID; UNCLASSIFIED DRUG;

ANALGESIA; ANTIINFLAMMATORY ACTIVITY; AQUEOUS SOLUTION; ARTICLE; BARK; COCHLOSPERMUM TINCTORIUM; CONTROLLED STUDY; DRUG ISOLATION; ETHNOPHARMACOLOGY; HOT PLATE TEST; MEDICINAL PLANT; NONHUMAN; PAW EDEMA; PHYTOCHEMISTRY; PLANT LEAF; PLANT ROOT; PRIORITY JOURNAL;

EID: 80051882137     PISSN: 09751483     EISSN: 09751505     Source Type: Journal    
DOI: 10.4103/0975-1483.83774     Document Type: Article

References (38)

1. Usman H, Yaro AH, Garba MM. Analgesic and Anti-inflammatory Screening of Newbouldia laevis flower in rodents. Trends Med Res2008;3:10-5. (Pubitemid 351791277)
2. Farnsworth N. Screening plant for new medicines. In: Wilson EO, Editor. Biodiversity. Washington DC: Natural Academy press; 1998.
3. Amos S, Kolawole E, Akah P, Wambebe C, Gamaniel K. Behavioral effects of the aqueous extract of Guiera senegalensis in mice and rats. Phytomedicine 2001;8:356-61. (Pubitemid 32983055)
4. Burkill HM. The useful plants of west tropical Africa. Kew: Botanical Gardens;1985.
5. Traoré M, Guiguemdé A, Yago I, Nikièma JB, Tinto H, Dakuyo ZP, et al. Investigation of Antiplasmodial compounds from two plants, Cochlospermum tinctorium A, Rich and Gardenia sokotensis. Afr J Tradit Complement Altern Med 2006;3:34-41. (Pubitemid 46157322)
6. Mann A, Gbate M, Umar AN. Medicinal and economic plants of Nupeland. Bida: Jube-Evans Books and Publications; 2003.
7. Nergard CS, Diallo D, Inngjerdingen K, Michaelsen TE, Kiyohara H, Yamada H, et al. Medicinal use of Cochlospermum tinctorium in Mali: Anti-ulcer-, radical scavenging-and immunomodulating activities of polymers in the aqueous extract of the roots. J Ethnopharmacol 2005;96:255-69. (Pubitemid 39575059)
8. Benoit F, Valentin A, Pelissier Y, Marion C, Dakuyo Z, Mallie M, et al. Antimalarial activity in vitro of Cochlospermum tinctorium tubercle extracts. Trans R Soc Trop Med Hyg 1995;89:217-8.
9. Diallo B, Vanhaelen M, Kiso Y, Hikino H. Antihepatotoxic actions of Cochlospermum tinctorium rhizomes. J Ethnopharmacol 1987;20:239-43. (Pubitemid 18075271)
10. Etuk EU, Agaie BM, Ladan MJ, Garba I. The modulatory effect of Cochlospermum tinctorium a rich aqueous root extract on liver damage induced by carbon tetrachloride in rats. Afr J Pharm Pharmacol 2009;3:151-7.
11. Tijjani MB, Bello IA, Aliyu AB, Olurishe T, Maidawa SM, Habila JD, et al. Phytochemical and antibacterial studies of root extract of Cochlospermum tinctorium A. rich. (Cochlospermaceae). Res J Med Plants2009;3:16-22.
12. Magaji MG, Shehu A, Musa AM, Sani MB, Yaro AH. Pharmacological evidence on the folkloric use of Cochlospermum tintorium A. Rich. in the management of diarrhea. Int J Pure Appl Sci 2010;4:14-20.
13. Maiha BB, Magaji MG, Yaro AH, Hamza AH, Magaji RA. Anticonvulsant Studies on Cochlospermum tinctorium and Paullinia pinnata extracts in laboratory animals.Niger J Pharm Sci 2009;8:102-8.
14. Silva GL, Lee I, Kinghorn AD. Special problems with the extraction of plants.In: Cannell RJ,editor. Methods in Biotechnology (Natural product Isolation). New Jersey: Humana Press;1998.
15. Lorke D. A new approach to acute toxicity testing. Arch Toxicol 1983;54:275-87. (Pubitemid 14205493)
16. Koster R, Anderson M, de Beer EJ. Acetic acid for analgesic screening. Fed Proc 1959;18:412.
17. Lanhers MC, Fleurentin J, Mortier F, Vinche A, Younos C. Antiinflammatory and analgesic effects of an aqueous extract of Harpagophytum procumbens. Planta Med 1992;58:117-23.
18. Mahomed IM, Ojewole JA. Analgesic, anti-inflammatory and Antidiabetic properties of Harpagophytum procumbens DC (Pedaliaceae) secondary root aqueous extract. Phytother Res 2004;18:982-9. (Pubitemid 40278922)
19. Winter CA, Riselay EA, Nuss GW. Carragenan induced oedema in the hind paw of the rats as an assay for anti-inflammatory drugs. Proc Soc Exp Biol Med 1962;111:544-7.
20. Matsumura F. Toxicology of Insecticides. New York: Plenum press;1975.
21. Trongsakul SA, Panthong D, Kanjanapothi T, Taesotikul T. The analgesic, antipyretic and anti-inflammatory activity of Diospyros variegate Kruz. J Ethnopharmacol 2003;85:221-5.
22. Sutharson L, Lila KN, Presanna KK, Shila EB, Rajan VJ. Antiinflammtory and Antinociceptive Activities of methanolic extract of the leaves of Fraxinus floribunda Wallich. Afr J Biotechnol 2007;6:582-5.
23. Bentley GA, Newtons SH, Starr J. Studies on the antinociceptive action of agonist drugs and their interaction with opioid mechanisms. Br J Pharmacol 1983;79:125-34. (Pubitemid 13128980)
24. Chan YF, Tsai HY, Wu TS. Anti-inflammatory and analgesic activity of extracts from roots of Angelica pubescens. Planta Med 1995;61:2-8.
25. Derardt R, Jongney S, Delvalcee F, Falhout M. Release of prostaglandins E and F in an algogenic reaction and its inhibition. Eur J Pharmacol 1980;51:17-24.
26. Dhara AK, Suba V, Sen T, Pal S, Chaudhuri AK. Preliminary studies on the anti-inflammatory and analgesic activity of methanolic fraction of the root of Tragia involucrate.J Ethnopharmacol 2000;72:265-8.
27. Barber A, Bartoszyk GD, Bender HM, Gottschlich R, Greiner HE, Harting J, et al. A Pharmacological profile of the novel peripherally-selective k-opioid receptor agonist, EMD 61753. Br J Pharmacol 1994;113:1317-27. (Pubitemid 24364416)
28. Brignola G, Calignano A, Di Rosa M. Modulation of morphine anti-nociception in the mouse by endogenous nitric oxide. Br J Pharmacol 1994;113:1372-6. (Pubitemid 24364423)
29. Mandegary A, Sayyah M, Heidari MR. Antinociceptive and Anti-Inflammatory activity of the seed and root extracts of Ferula gummosa Boiss in mice and rats. DARU J Pharm Sci 2004;12:58-62. (Pubitemid 38993766)
30. Parkhouse J, Pleuvry BJ. Analgesic drugs. Oxford: Blackwell Co.; 1979.
31. Vinegar R, Schreiber W, Hugo R.Biphasic development of carrageenin edema in rats.J Pharmacol Exp Ther 1969;166:96-103.
32. Crunkhon P, Meacock SE. Mediators of inflammation induced in rats paw by carrageenan. Br J Pharmacol 1971;42:392-402.
33. Burke A, Smyth E, FitzGerald GA. Analgelsic-antipyretic agents; Pharmacotherapy of Gout. In: Brunton LL, Lazo JS, Parker KL,editors. Goodman and Gilman: Pharmacological basis of therapeutics. 11 th ed. New York: McGraw Hill Co Inc.; 2006.
34. Roberts JL, Morrow JD. Analgesic, Antipyretic and Anti-inflammatory Agents and Drugs employed in the treatment of Gout. In: Hardman JG, Limbird LE, editors. Goodman and Gilman's the pharmacological basis of therapeutics. 10 th ed. New York: McGraw Hill Co Inc.; 2002.
35. Ahmadiani A, Hosseiny J, Semnanian S, Javan M, Saeedi F, Kamalinejad M, et al. Antinociceptive and anti-inflammatory effects of Elaeagnus angustifolia fruit extract. J Ethnopharmacol 2000;72:287-92.
36. Reanmongkol W, Subhadhirasakul S, Thienmontree S, Thanyapanit K, Kalnaowakul J, Sengsui S. Antinociceptive activity of the alkaloid extract from Kopsia macrophylla leaves in mice. Songklanakarin J Sci Technol 2005; 27(Supplement-2): 509-12 URL: http://www.rdoapp.psu.ac.th/html/sjst/journal/27- Suppl-2/07-Kopsia-macrophylla.pdf
37. de Araujo PF, Coelho-de-Souza AN, Morais SM, Ferreira SC, Leal-Cardoso JH. Antinociceptive effects of the essential oil of Alpinia zerumbet on mice. Phytomedicine 2005;12:482-6. (Pubitemid 40755123)
38. Choi J, Jung H, Lee K, Park H. Antinociceptive and Antiinflammatory effects of saponin and sapogenin obtained from the stem of Akebia quinata. J Med Food 2005;8:78-85. (Pubitemid 40617042)