Effect of weight loss on upper airway size and facial fat in men with obstructive sleep apnoea

Thorax

Volumn 66, Issue 9, 2011, Pages 797-803

  Sutherland, Kate ^a,b   Lee, Richard W W ^a,b   Phillips, Craig L ^a,b   Dungan, George ^a   Yee, Brendon J ^a,c   Magnussen, John S ^c   Grunstein, Ronald R ^a,c   Cistulli, Peter A ^a,b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b ROYAL NORTH SHORE HOSPITAL   (Australia)

^c ROYAL PRINCE ALFRED HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

SIBUTRAMINE;

ABDOMINAL FAT; ADIPOSE TISSUE; ADULT; AGED; ANTHROPOMETRY; APNEA HYPOPNEA INDEX; ARTICLE; BRONCHIOLE; COMPUTER ASSISTED TOMOGRAPHY; COMPUTER PROGRAM; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; FACIAL FAT; HUMAN; IMAGE ANALYSIS; INTRAABDOMINAL FAT; LIPID ANALYSIS; LUNG VOLUME; MAJOR CLINICAL STUDY; MALE; OBESITY; ORGAN SIZE; POLYSOMNOGRAPHY; PRIORITY JOURNAL; SLEEP APNEA SYNDROME; THERAPY EFFECT; TREATMENT DURATION; UPPER RESPIRATORY TRACT; WEIGHT REDUCTION;

EID: 80051875111     PISSN: 00406376     EISSN: 14683296     Source Type: Journal    
DOI: 10.1136/thx.2010.151613     Document Type: Article

References (36)

1. Young T., Peppard P.E., Taheri S. Excess weight and sleep-disordered breathing. J Appl Physiol 2005;99:1592-1599 (Pubitemid 43014371)
2. Grunstein R.R., Stenlöf K., Hedner J.A., et al. Two year reduction in sleep apnea symptoms and associated diabetes incidence after weight loss in severe obesity. Sleep 2007;30:703-710 (Pubitemid 46854757)
3. Johansson K., Neovius M., Lagerros Y.T., et al. Effect of a very low energy diet on moderate and severe obstructive sleep apnoea in obese men: A randomised controlled trial. BMJ 2009;339:b4609.
4. Yee B.J., Phillips C.L., Banerjee D., et al. The effect of sibutramine-assisted weight loss in men with obstructive sleep apnoea. Int J Obes (Lond) 2007;31:161-168 (Pubitemid 46006030)
5. Schwartz A.R., Patil S.P., Laffan A.M., et al. Obesity and obstructive sleep apnea: Pathogenic mechanisms and therapeutic approaches. Proc Am Thorac Soc 2008;5:185-192 (Pubitemid 351237877)
6. Schwab R.J., Pasirstein M., Pierson R., et al. Identification of upper airway anatomic risk factors for obstructive sleep apnea with volumetric magnetic resonance imaging. Am J Respir Crit Care Med 2003;168:522-530 (Pubitemid 37088593)
7. Watanabe T., Isono S., Tanaka A., et al. Contribution of body habitus and craniofacial characteristics to segmental closing pressures of the passive pharynx in patients with sleep-disordered breathing. Am J Respir Crit Care Med 2002;165:260-265 (Pubitemid 34084468)
8. Schwab R.J., Pack A.I., Gupta K.B., et al. Upper airway and soft tissue structural changes induced by CPAP in normal subjects. Am J Respir Crit Care Med 1996;154:1106-1116
9. Chan A.S., Sutherland K., Schwab R.J., et al. The effect of mandibular advancement on upper airway structure in obstructive sleep apnoea. Thorax 2010;65:726-732
10. Hernandez T.L., Ballard R.D., Weil K.M., et al. Effects of maintained weight loss on sleep dynamics and neck morphology in severely obese adults. Obesity (Silver Spring) 2009;17:84-91. (Pubitemid 50310539)
11. Rubinstein I., Colapinto N., Rotstein L.E., et al. Improvement in upper airway function after weight loss in patients with obstructive sleep apnea. Am Rev Respir Dis 1988;138:1192-1195 (Pubitemid 18264489)
12. Vgontzas A.N. Does obesity play a major role in the pathogenesis of sleep apnoea and its associated manifestations via inflammation, visceral adiposity, and insulin resistance? Arch Physiol Biochem 2008;114:211-223
13. Levine J.A., Ray A., Jensen M.D. Relation between chubby cheeks and visceral fat. N Engl J Med 1998;339:1946-1947 (Pubitemid 29013947)
14. Sierra-Johnson J., Johnson B.D. Facial fat and its relationship to abdominal fat: A marker for insulin resistance? Med Hypotheses 2004;63:783-786 (Pubitemid 39369995)
15. Lee R.W., Sutherland K., Chan A.S., et al. Relationship between surface facial dimensions and upper airway structures in obstructive sleep apnea. Sleep 2010;33:1249-1254
16. Lee R.W., Petocz P., Prvan T., et al. Prediction of obstructive sleep apnea with craniofacial photographic analysis. Sleep 2009;32:46-52.
17. Phillips C.L., Yee B.J., Trenell M.I., et al. Changes in regional adiposity and cardiometabolic function following a weight loss program with sibutramine in obese men with obstructive sleep apnea. J Clin Sleep Med 2009;5:416-421
18. Barkdull G.C., Kohl C.A., Patel M., et al. Computed tomography imaging of patients with obstructive sleep apnea. Laryngoscope 2008;118:1486-1492
19. Welch K.C., Foster G.D., Ritter C.T., et al. A novel volumetric magnetic resonance imaging paradigm to study upper airway anatomy. Sleep 2002;25:532-542 (Pubitemid 34787379)
20. Abramson Z., Susarla S., August M., et al. Three-dimensional computed tomographic analysis of airway anatomy in patients with obstructive sleep apnea. J Oral Maxillofac Surg 2010;68:354-362
21. Malhotra A., Huang Y., Fogel R.B., et al. The male predisposition to pharyngeal collapse: Importance of airway length. Am J Respir Crit Care Med 2002;166:1388-1395 (Pubitemid 35292707)
22. Pae E.K., Lowe A.A., Fleetham J.A. A role of pharyngeal length in obstructive sleep apnea patients. Am J Orthod Dentofacial Orthop 1997;111:12-17.
23. Owens R.L., Malhotra A., Eckert D.J., et al. The influence of end-expiratory lung volume on measurements of pharyngeal collapsibility. J Appl Physiol 2010;108:445-451
24. Burger C.D., Stanson A.W., Daniels B.K., et al. Fast-CT evaluation of the effect of lung volume on upper airway size and function in normal men. Am Rev Respir Dis 1992;146:335-339
25. Hoffstein V., Zamel N., Phillipson E.A. Lung volume dependence of pharyngeal cross-sectional area in patients with obstructive sleep apnea. Am Rev Respir Dis 1984;130:175-178 (Pubitemid 14055799)
26. Schwartz A.R., Patil S.P., Squier S., et al. Obesity and upper airway control during sleep. J Appl Physiol 2010;108:430-435
27. Johal A., Patel S.I., Battagel J.M. The relationship between craniofacial anatomy and obstructive sleep apnoea: A case-controlled study. J Sleep Res 2007;16:319-326 (Pubitemid 47283924)
28. Hora F., Nápolis L.M., Daltro C., et al. Clinical, anthropometric and upper airway anatomic characteristics of obese patients with obstructive sleep apnea syndrome. Respiration 2007;74:517-524 (Pubitemid 47206881)
29. Schäfer H., Pauleit D., Sudhop T., et al. Body fat distribution, serum leptin, and cardiovascular risk factors in men with obstructive sleep apnea. Chest 2002;122:829-839
30. Tsuiki S., Isono S., Ishikawa T., et al. Anatomical balance of the upper airway and obstructive sleep apnea. Anesthesiology 2008;108:100-115
31. Peppard P.E., Young T., Palta M., et al. Longitudinal study of moderate weight change and sleep-disordered breathing. JAMA 2000;284:3015-3021 (Pubitemid 32014738)
32. Kamel E.G., McNeill G., Van Wijk M.C. Change in intra-abdominal adipose tissue volume during weight loss in obese men and women: Correlation between magnetic resonance imaging and anthropometric measurements. Int J Obes Relat Metab Disord 2000;24:607-613 (Pubitemid 30323493)
33. Simpson L., Mukherjee S., Cooper M.N., et al. Sex differences in the association of regional fat distribution with the severity of obstructive sleep apnea. Sleep 2010;33:467-474
34. Martinez D., Basile B.R. Sibutramine does not worsen sleep apnea syndrome: A randomized double-blind placebo-controlled study. Sleep Med 2005;6:467-470 (Pubitemid 41245370)
35. Yoon D.Y., Moon J.H., Kim H.K., et al. Comparison of low-dose CT and MR for measurement of intra-abdominal adipose tissue: A phantom and human study. Acad Radiol 2008;15:62-70. (Pubitemid 350217017)
36. Vos W., De Backer J., Devolder A., et al. Correlation between severity of sleep apnea and upper airway morphology based on advanced anatomical and functional imaging. J Biomech 2010;40:2207-2213 (Pubitemid 46977403)