Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) activity decreases estrogenesis in ovarian granulosa cells

Cytometry Part A

Volumn 79 A, Issue 9, 2011, Pages 669-671

  Löhrke, Berthold ^a   Weitzel, Joachim M ^a   Krüger, Burkhard ^b   Xu, Jinxian ^a   Vernunft, Andreas ^a   Viergutz, Torsten ^a  

^a LEIBNIZ INSTITUTE FOR FARM ANIMAL BIOLOGY FBN   (Germany)

^b UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATASE; ESTROGEN; FUMONISIN; LUTEINIZING HORMONE; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; TESTOSTERONE;

ANIMAL; CALCIUM SIGNALING; CATTLE; DRUG EFFECT; FEMALE; GRANULOSA CELL; LETTER; METABOLISM;

ANIMALS; AROMATASE; CALCIUM SIGNALING; CATTLE; ESTROGENS; FEMALE; FUMONISINS; GRANULOSA CELLS; LUTEINIZING HORMONE; SCAVENGER RECEPTORS, CLASS E; TESTOSTERONE;

EID: 80051874736     PISSN: 15524922     EISSN: 15524930     Source Type: Journal    
DOI: 10.1002/cyto.a.21082     Document Type: Letter

References (12)

1. Espey LL. Comprehensive analysis of ovarian gene expression during ovulation using differential display. Methods Mol Biol 2006; 317: 219-241.
2. Spanel-Borowski K. Ovulation as danger signaling event of innate immunity. Mol Cell Endocrinol 2011; 333: 1-7.
3. Sakamoto N, Ishibashi T, Sugimoto K, Sawamura T, Sakamoto T, Inoue N, Saitoh S, Kamioka M, Uekita H, Ohkawara H, Suzuki K, Teramoto T, Maruyama Y, Takeishi Y. Role of LOX-1 in monocyte adhesion-triggered redox. Akt/eNOS and Ca2+ signaling pathways in endothelial cells. J Cell Physiol 2009; 220: 706-715.
4. Vilser C, Hueller H, Nowicki M, Hmeidan FA, Blumenauer V, Spanel-Borowski K. The variable expression of lectin-like oxidized low-density lipoprotein receptor (LOX-1) and signs of autophagy and apoptosis in freshly harvested human granulosa cells depend on gonadotropin dose, age, and body weight. Fertil Steril 2010; 93: 2706-2715.
5. Löhrke B, Viergutz T, Shahi SK, Pöhland R, Wollenhaupt K, Goldammer T, Walzel H, Kanitz W. Detection and functional characterisation of the transcription factor peroxisome proliferator-activated receptor gamma in lutein cells. J Endocrinol 1998; 159: 429-439.
6. Viergutz T, Löhrke B. Role of the platelet-activating factor and its receptor in the proliferative regulation of bovine ovarian granulosa cells. Cell Prolif 2007; 40: 949-960.
7. Löhrke B, Xu J, Weitzel JM, Krüger B, Goldammer T, Viergutz T N-acetylcysteine impairs survival of luteal cells through mitochondrial dysfunction. Cytometry Part A 2010; 77A: 310-320.
8. Aguirre C, Jayes FC, Veldhuis JD. Luteinizing hormone (LH) drives diverse intracellular calcium second messenger signals in isolated porcine ovarian thecal cells: Preferential recruitment of intracellular Ca2+ oscillatory cells by higher concentrations of LH. Endocrinology 2000; 141: 2220-2228.
9. Serke H, Bausenwein J, Hirrlinger J, Nowicki M, Vilser C, Jogschies P, Hmeidan FA, Blumenauer V, Spanel-Borowski K. Granulosa cell subtypes vary in response to oxidized low-density lipoprotein as regards specific lipoprotein receptors and antioxidant enzyme activity. J Clin Endocrinol Metab 2010; 95: 3480-3490.
10. Löhrke B, Viergutz T, Krüger B. Polar phospholipids from bovine endogenously oxidized low density lipoprotein interfere with follicular thecal function. J Mol Endocrinol 2005; 35: 531-545.
11. Sargis RM, Subbaiah PV. Protection of membrane cholesterol by sphingomyelin against free radical-mediated oxidation. Free Radic Biol Med 2006; 40: 2092-2102.
12. Löhrke B, Derno M, Hammon H, Metges C, Melcher J, Viergutz T, Jentsch W, Zühlke H. Nutritional level and energetic source are determinants of elevated circulatory lipohydroperoxide concentration. Br J Nutr 2008; 99: 1255-1265.